Clinical and epidemiological characteristics of patients seeking COVID-19 testing in a private centre in Malaysia: Is there a role for private healthcare in battling the outbreak?말레이시아 민간 센터에서 COVID-19 검사를 원하는 환자의 임상 및 역학적 특성: 발병과 싸우는 데 민간 의료의 역할이 있습니까?Research Article Published on 2021-10-142022-09-12 Journal: PLoS ONE [Category] MERS, 진단, [키워드] 95% CI accounted Analysis Asymptomatic average baseline characteristics characteristics of patient clearance clinical clinical care Cluster confirmed case confirmed cases COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 testing cross-sectional cumulative Descriptive statistics disease epidemiological exposure to Fever followed by had no health institution healthcare Hospital admission identify IMPROVE Logistic regression analysis Loss of Smell loss of smell or taste majority Malaysia molecular Molecular assay molecular assays MOST multivariate logistic regression multivariate logistic regression analysis National objective observation observational study Patient positive Predictive risk risk factor Risk factors running nose SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity seeking Selangor significantly study cohort subject subjects Symptom Taste tested Travel was used [DOI] 10.1371/journal.pone.0258671 PMC 바로가기 [Article Type] Research Article
Receptor-Loaded Virion Endangers GPCR Signaling: Mechanistic Exploration of SARS-CoV-2 Infections and Pharmacological Implications수용체가 장착된 Virion은 GPCR 신호 전달을 위험에 빠뜨립니다: SARS-CoV-2 감염 및 약리학적 의미의 기계적 탐색Review Published on 2021-10-112022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 치료제, [키워드] ACE2 ACE2 receptor alleviate antibody Antibody therapy arrestin binding Brain Cell cell junction cellular response COVID-19 demonstrated disrupting Disruption distribution drug Drug development E protein ENhance exploration GPCR signaling hematogenous host cells impair Infection interact Interaction intestine Invasion kidney Loss of Smell loss of smell and taste lung Lungs membrane motif multiorgan injury multiple organs NRP1 other organ other organs PALS1 pathogenic PDZ interaction penetration Protein receptor required respiratory respiratory tract SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections susceptible Taste therapeutic strategy therapy tissue Viral viral cell entry viral endocytosis viral invasion virion virtue ZO-1 [DOI] 10.3390/ijms222010963 PMC 바로가기 [Article Type] Review
Can Salivary Innate Immune Molecules Provide Clue on Taste Dysfunction in COVID-19?Microbiology Published on 2021-10-112022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme-2 Can Coronavirus Disease (COVID)-19 Coronavirus-2 correlated COVID-19 COVID-19 patients dysgeusia Effect elevated entry receptor expression health informatics host response Innate measure microbial molecule oral mucosa pandemic receptor recognition protein regulate sACE2 Saliva SARS-CoV2 soluble ACE2 supported suppress Taste viral infection Viral load virus [DOI] 10.3389/fmicb.2021.727430 PMC 바로가기 [Article Type] Microbiology
Predictive symptoms for COVID-19 in the community: REACT-1 study of over 1 million people지역 사회에서 COVID-19에 대한 예측 증상 : 백만 명 이상의 REACT-1 연구Comparative Study Published on 2021-09-282022-09-10 Journal: PLoS Medicine [Category] SARS, 치료기술, [키워드] (alpha acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age approach asked assessment AUC B.1.1.7 B.1.1.7 lineage B.1.1.7 variant best carried chills collected Combination Community community transmission Contact tracing coronavirus cough country COVID-19 COVID-19 case COVID-19 infection Cycle threshold value detection rate determine eligibility Elliot England estimate Evidence Fever Genome sequencing groups identify IMPROVE individual Infection investigated involved Isolation Joshua limit limitation Lineage logistic regression model logistic regression models measure muscle aches N-gene National Health Service nose swab participant PCR positivity PCR test PCR testing PCR-positive performed persistent cough positive predict predicted Predictive Prevalence random Rapid recall bia repeated reported researcher respiratory response rates resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR test selected Self-reported symptoms sense sense of smell sense of taste severe acute respiratory syndrome Coronavirus sore throat Spread subsampling Symptom symptomatic case symptomatic cases symptomatic individual symptomatic individuals Symptoms Taste test results tested these symptom these symptoms throat and nose swabs Transmission Univariate analysis Viral genome sequencing Volunteer Weighting wild type wild-type virus would increase [DOI] 10.1371/journal.pmed.1003777 PMC 바로가기 [Article Type] Comparative Study
Evaluation of the xerostomia, taste and smell impairments after Covid-19Research Published on 2021-09-272022-10-31 Journal: Medicina Oral, Patología Oral y Cirugía Bucal [Category] COVID-19, SARS, [키워드] applied coronavirus disease Effect eight evaluated female females Gender hospital impairment in some involved male Material and Method Patient questionnaire reached Result salivary significant difference stimulated Taste the patient Treatment [DOI] 10.4317/medoral.24510 PMC 바로가기 [Article Type] Research
Non-specific oral and cutaneous manifestations of Coronavirus Disease 2019 in childrenResearch Published on 2021-09-272022-10-31 Journal: Medicina Oral, Patología Oral y Cirugía Bucal [Category] COVID-19, SARS, [키워드] Affect affected age analyzed body temperature Brescia Child childhood children children with COVID-19 clinic coated cough COVID-19 cutaneous manifestation Cutaneous manifestations elevated flat geographic tongue knowledge lesion lesions less manifestation Material and Method medical record non-specific oral mucosa papular Patient patients Pediatric patient reported Result Retrospective cross-sectional study Taste temperature the disease tongue [DOI] 10.4317/medoral.24461 PMC 바로가기 [Article Type] Research
Altered smell and taste: Anosmia, parosmia and the impact of long Covid-19Research Article Published on 2021-09-242022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] alteration Altered Care conducted daily living dysfunction emotional exploratory Facebook Health Health status Impact Infection initial lack Loss olfactory participant physical professional Psychological well-being Qualitative Quality of life reduced reported Research Result sense of taste Side effect Smell Smell loss Support Symptom Taste thematic analysis Treatment weight loss [DOI] 10.1371/journal.pone.0256998 PMC 바로가기 [Article Type] Research Article
Qualitative smell/taste disorders as sequelae of acute COVID-19급성 COVID-19의 후유증으로서의 질적 후각/미각 장애Covid-19 Published on 2021-09-232022-09-10 Journal: Neurological Sciences [Category] SARS, 치료기술, [키워드] acute COVID-19 age characterized consecutive patient COVID-19 COVID-19 patient described detection disorder domains dysfunction enrolled healthy controls investigated loss of smell/taste Nasopharyngeal swab no significant difference no significant differences objective olfactory Olfactory hallucination parageusia parosmia pathophysiology Patient patients Phantogeusia phantosmia Qualitative Quantitative questionnaire reported Result Sex Smell strip suffered Taste Test tested were used [DOI] 10.1007/s10072-021-05611-6 PMC 바로가기 [Article Type] Covid-19
Electrophysiological and olfactometric evaluation of long‐term COVID‐19장기 COVID -19의 전기 생리 학적 및 후각 측정 평가Case Reports Published on 2021-09-182022-09-10 Journal: Physiological Reports [Category] SARS, 변종, [키워드] Activation acute respiratory disease Anosmia assessments Asymptomatic Brain Case report clinical manifestation clinical manifestations Consequences COVID‐19 diagnose Effect First wave Health health history impairment lack long term long‐term COVID‐19 multiple organ dysfunction neurological OERP olfactometric evaluation olfactory olfactory bulb olfactory function Patient periphery public health emergency Quantitative Respiratory disease SARS‐CoV‐2 sense sense of smell subject subsequent syndrome Taste the epidemic variant VOCs [DOI] 10.14814/phy2.14992 PMC 바로가기 [Article Type] Case Reports
Performance of COVID-19 associated symptoms and temperature checking as a screening tool for SARS-CoV-2 infectionSARS-CoV-2 감염 선별 도구로서의 코로나19 관련 증상 수행 및 체온 측정Research Article Published on 2021-09-172022-09-12 Journal: PLoS ONE [Category] MERS, 진단, [키워드] Affect analysed Analysis approach Asymptomatic benefit carried clinical symptom Clinical symptoms Contact coronavirus disease cough country COVID-19 COVID-19 associated symptom COVID-19 disease cut-off detect determine diagnosing diagnosis of COVID-19 disease effective facemask Fever Final final diagnosis hand hygiene hospital hygiene Isolation lack lockdown loss of sense of smell MOST P-value participant performance positive presenting pressure preventing infection public space quarantine receiver operator characteristics Result ROC ROC analysis SARS-CoV-2 SARS-CoV-2 infected patients SARS-COV-2 infection SARS-CoV-2 positivity sense sense of smell sense of taste sensitivity significantly higher social distancing spread to Symptom Tamale Taste Teaching temperature Transmission true positive vaccination [DOI] 10.1371/journal.pone.0257450 PMC 바로가기 [Article Type] Research Article