Chickens Expressing IFIT5 Ameliorate Clinical Outcome and Pathology of Highly Pathogenic Avian Influenza and Velogenic Newcastle Disease VirusesOriginal Research Published on 2018-09-142023-05-31 Journal: Frontiers in Immunology [Category] Fulltext, 조류인플루엔자, [키워드] antiviral response host registance Innate immunity transgenic viruses [DOI] 10.3389/fimmu.2018.02025 PMC 바로가기 [Article Type] Original Research
Functional Conservation of P48/45 Proteins in the Transmission Stages of Plasmodium vivax (Human Malaria Parasite) and P . berghei (Murine Malaria Parasite)플라스모디움 비박스(인간 말라리아 기생충)와 P. 베르게이(쥐 말라리아 기생충)의 전파 단계에서 P48/45 단백질의 기능적 보존Research Article Published on 2018-09-042024-08-11 Journal: mBio [Category] 말라리아, [키워드] malaria P48/45 transgenic Transmission [DOI] 10.1128/mBio.01627-18 PMC 바로가기 [Article Type] Research Article
Maintaining Quality of Candidate Strains of Transgenic Mosquitoes for Studies in Containment Facilities in Disease Endemic CountriesArticle Published on 2018-01-312024-09-09 Journal: Vector Borne Zoonotic Dis [Category] 말라리아, [키워드] Containment insectary mosquitoes Quality assurance transgenic PMC 바로가기
Studies of Transgenic Mosquitoes in Disease-Endemic Countries: Preparation of Containment FacilitiesArticle Published on 2018-01-312024-09-09 Journal: Vector Borne Zoonotic Dis [Category] 말라리아, [키워드] biosafety Compliance Containment insectary mosquitoes transgenic PMC 바로가기
Containment Studies of Transgenic Mosquitoes in Disease Endemic Countries: The Broad Concept of Facilities ReadinessArticle Published on 2018-01-312024-09-09 Journal: Vector Borne Zoonotic Dis [Category] 말라리아, [키워드] biosafety Compliance Containment insectary mosquitoes transgenic PMC 바로가기
MicroRNA-275 targets sarco/endoplasmic reticulum Ca 2+ adenosine triphosphatase (SERCA) to control key functions in the mosquito gutMicroRNA-275는 모기장에서 주요 기능을 제어하기 위해 sarco/endoplasmic reticulum Ca 2+ adenosine triphosphatase(SERCA)를 표적으로 합니다.Research Article Published on 2017-08-072022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Actin activating active transport addition adenosine Aede affecting approach Arboviruses assembly Blood blood meal cancers cardiac hypertrophy caused Chikungunya Combination conserved contribute contributing to correlated Critical cytosol decoy decrease Dengue deplete digestion digestive digestive enzyme enzyme female Fever fevers finding function functions Gut gut microbiota guts heart failure homeostasis human diseases humans implicated injection Injections investigated involved knowledge leads maintenance mechanism microRNA miRNA Mosquito mRNA Notch pathogen pathogen transmission Pathogens phenotype Proteases Protein protein level protein levels reduction regulate Regulation remained repeated required rescued RNA sequence SERCA shown signaling pathway significantly spatiotemporal target the mosquito tissue Transcription transgenic Transport trypsin vectors yeast yellow fever yellow fevers Zika [DOI] 10.1371/journal.pgen.1006943 PMC 바로가기 [Article Type] Research Article
The use of transgenic parasites in malaria vaccine researcharticle Published on 2017-07-312024-09-01 Journal: Expert review of vaccines [Category] 말라리아, [키워드] chimeric Gap malaria Plasmodium reporter transgenic Vaccine [Article Type] article
Functional Analysis Reveals Geographical Variation in Inhibitory Immune Responses Against a Polymorphic Malaria Antigen기능적 분석이 다형성 말라리아 항원에 대한 억제 면역 반응의 지리적 변variation을 밝혀냅니다.Article Published on 2017-07-152024-08-12 Journal: Nanoscale [Category] 말라리아, [키워드] Growth inhibition Invasion PfRh2b transgenic Vaccine [DOI] 10.1093/infdis/jix280 PMC 바로가기
Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variantsResearch Article Published on 2017-05-182022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] Antiviral Antiviral agents antiviral drug antiviral strategy applied approach binding blocked catalytic catalytic activity cellular cleaving complicate component Critical develop domain DUB Ebola effective enzyme Enzymes expression Health Hemorrhagic fever virus high affinity Host humans identify infect infected patient Infection prevention inhibit inhibited inhibitor inhibitors innate immune responses interferon ISG15 magnitude MERS-CoV MERS-CoV infection Middle East molecular interaction mRNA outbreak Outbreaks Papain-like protease pathogenic virus pathogenicity plants polyprotein potent progeny PROTECT Protein Protein design provide reduced Replication replicative respiratory syndrome coronavirus responsible selective similarity specificity stimulated suppress targets therapeutic therapy transgenic Treatment variant variety viral pathogen viral replicase polyprotein viral replication virus viruses while Zika virus [DOI] 10.1371/journal.ppat.1006372 PMC 바로가기 [Article Type] Research Article
Tree shrew ( Tupaia belangeri ) as a novel laboratory disease animal modelArticle Published on 2017-05-182023-08-30 Journal: Zoological research [Category] E형 간염, [키워드] animal model disease transgenic Tree shrew (Tupaia belangeri) [DOI] 10.24272/j.issn.2095-8137.2017.033 PMC 바로가기