Simple, Low-Cost and Long-Lasting Film for Virus Inactivation Using Avian Coronavirus Model as ChallengeArticle Published on 2020-09-042022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Antiviral caused challenge Contact contaminated surface coronavirus COVID-19 infection detergent Direct dose Efficacy expected film flammable inactivated inactivation infective maintain Model morphologically polystyrene Population populations quantification RNA virus RT-qPCR sanitization SARS-CoV-2 shown simple Spread spread of COVID-19 virucidal virucide virus virus infectivity was determined was used [DOI] 10.3390/ijerph17186456 PMC 바로가기 [Article Type] Article
Cholesterol-modifying drugs in COVID-19Short Communication Published on 2020-06-182022-10-29 Journal: Oxford Open Immunology [Category] COVID-19, [키워드] Alter anti-inflammatory effect Antiviral cardiovascular disease cholesterol cholesterol-modifying drugs coronavirus COVID-19 drug dyslipidaemia dyslipidemia Effect highlight Immune cell Immunity immunomodulatory in vitro in vivo models Inflammation management mechanism membranes obesity outcome pleiotropic promote protective immunity Replication resulting SARS-CoV-2 SARS-COV-2 infection statin statins syndrome systemic inflammatory responses T-cells tested the SARS-CoV-2 viral immunology virus virus infectivity [DOI] 10.1093/oxfimm/iqaa001 PMC 바로가기 [Article Type] Short Communication
Propagation, Inactivation, and Safety Testing of SARS-CoV-2Article Published on 2020-06-062022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Biosafety Level 3 causes Cellulose Chinese coronavirus COVID-19 deaths described DNA effective facilitated focus forming assay inactivation infected cell Infection Infectious virus multiple cell line neutral buffered formalin new virus Novel coronavirus pandemic performed Plaque assay Propagation Protein quantification Research responsible resulting RNA Safe Safety SARS-CoV-2 Testing the disease Trizol Virology virus virus infectivity widespread worldwide pandemic Wuhan [DOI] 10.3390/v12060622 PMC 바로가기 [Article Type] Article
Harnessing the power of novel animal-free test methods for the development of COVID-19 drugs and vaccinesGuest Editorial Published on 2020-05-232022-10-28 Journal: Archives of Toxicology [Category] COVID-19, MERS, SARS, [키워드] accelerated antibody approach approaches biological processe carcinogenicity country COVID-19 Critical drug Drug discovery Efficacy EMA epitope European Medicines Agency feature Health Laboratory limitation Molecular biology Organoid pandemic pathogen predict resource SARS-CoV2 supplementary material Vaccine virus virus infectivity [DOI] 10.1007/s00204-020-02787-2 PMC 바로가기 [Article Type] Guest Editorial
Temporary carriage of bovine coronavirus and bovine respiratory syncytial virus by fomites and human nasal mucosa after exposure to infected calvesResearch Article Published on 2018-01-222022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] biosecurity bovine Bovine coronavirus Bovine respiratory disease cattle Cell culture collected Contact determine Endemic equipment experiments high viral load Human nasal mucosa Indirect transmission Infection infective knowledge mucosal swab nasal mucosa pathogen positive Prevent quantified respiratory syncytial virus Result risk RNA RT-PCR RT-qPCR selected short-lived Spread Swab swabs temporary tested Transmission transmission potential viral particle Viral RNA viral RNA load virion virions virus virus infectivity viruses [DOI] 10.1186/s12917-018-1335-1 PMC 바로가기 [Article Type] Research Article
Role of the lipid rafts in the life cycle of canine coronavirusStandard Published on 2015-02-012022-10-30 Journal: The Journal of General Virology [Category] Coronavirus, [키워드] Antiviral Antiviral strategies canine cell entry cell membrane cell membranes cholesterol complex Concentration coronavirus Coronaviruses disrupt dose-dependent dose-dependent reduction enveloped RNA virus host cells in viral Infection infection rate infections inhibitory inhibitory effect involved Lipid lipid composition lipid metabolism mechanism membrane modulate plasma membrane Protein Proteins reduction in required role sphingolipids Treatment viral entry viral particle virus virus infectivity was reduced was used [DOI] 10.1099/vir.0.070870-0 PMC 바로가기 [Article Type] Standard
Plaque assay for human coronavirus NL63 using human colon carcinoma cellsMethodology Published on 2008-11-122022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] African green monkey Antiviral Avicel carboxymethyl-cellulose Cell Cell culture colds Colon coronavirus cytopathogenic effect days post infection demonstrated different disease Drug screening Effects HCoV HCoV-NL63 Human human pathogen humans Infection kidney log NL63 plaque Plaque assay plaque assays produced purification quantification replicated Result Support susceptibility tested utility viral infectivity virus virus infectivity virus replication virus stock [DOI] 10.1186/1743-422X-5-138 PMC 바로가기 [Article Type] Methodology