wound healing

[키워드] also known as Akt also known as E3 ubiquitin-protein ligase Mdm2 group 2A group 2D (p)Rb(phosphorylated) retinoblastoma protein (phosphorylated) retinoblastoma protein AKTProtein kinase B An activating Natural Killer (NK) cell receptor Anti-apoptotic B-cell lymphoma Ataxia telangiectasia and Rad3-related protein Ataxia-telangiectasia mutated ATMAtaxia-telangiectasia mutated ATRAtaxia telangiectasia and Rad3-related protein BclAnti-apoptotic B-cell lymphoma Biomarker Cell cell cycle arrest cellular senescence Characteristics Checkpoint kinase 2 Chk2Checkpoint kinase 2 clearance contribute DDRDNA damage response disease DNA damage response DNA segments with chromatin alterations reinforcing senescence DNA-SACRSDNA segments with chromatin alterations reinforcing senescence ERKextracellular signal-regulated kinases examined extracellular signal-regulated kinases Forkhead box protein O4 FOXO4Forkhead box protein O4 genotoxic hallmark health system heat shock protein highlight HSP90Heat shock protein IkBInhibitor of nuclear factor kappa B IKKIκB kinase ILInterleukin IMMP2LInner mitochondrial membrane peptidase subunit 2 immune system Inhibitor of nuclear factor kappa B Inner mitochondrial membrane peptidase subunit 2 interleukin Interleukin-1 receptor-associated kinase 1 investigated IRAK1Interleukin-1 receptor-associated kinase 1 IκB kinase Mammalian target of rapamycin complex 1/2 MAPKmitogen-activated protein kinase MDM2Mouse double minute 2 homolog mechanism mitogen-activated protein kinase Mitogen-activated protein kinase-activated protein kinase 2 MK2Mitogen-activated protein kinase-activated protein kinase 2 Mouse double minute 2 homolog mTORC1/2Mammalian target of rapamycin complex 1/2 NADPHNicotinamide adenine dinucleotide phosphate NEMONF-kappa-B essential modulator NF-kappa-B essential modulator NF-kBNuclear factor – κB Nicotinamide adenine dinucleotide phosphate NKG2AAn activating Natural Killer (NK) cell receptor NKG2DAn activating Natural Killer (NK) cell receptor Nuclear factor – κB occur OISOncogene-induced senescence Oncogene-induced senescence organism phosphatase and tensin homolog Phosphoinositide 3-kinases physiological PI3KPhosphoinositide 3-kinases PICSPTEN-loss–induced cellular senescence Potential potential therapeutic target Premature Protein kinase B PTEN-loss–induced cellular senescence PTENphosphatase and tensin homolog reactive oxygen species replicative Research ROSreactive oxygen species SA-β-GalSenescence-associated beta-galactosidase SAHFSenescence-associated heterochromatin foci SAMSenescence-accelerated mice SASPsenescence-associated secretory phenotype Senescence-accelerated mice Senescence-associated beta-galactosidase Senescence-associated heterochromatin foci senescence-associated secretory phenotype senescent cell SIRT1Sirtuin 1 Sirtuin 1 Stressor target therapeutic approaches therapy Therapy induced senescence TISTherapy induced senescence wound healing
[DOI] 10.1016/j.arr.2020.101251 [Article Type] Review article