cause – Page 60 – Communicable Diseases Research

Acute and Chronic Cardiovascular Manifestations of COVID-19: Role for Endotheliopathy

Review

Published on 2021-12-152022-10-30
Journal: Methodist DeBakey Cardiovascular Journal [Category] COVID-19, MERS, SARS,

[키워드] Adhesion Molecule alteration antioxidant Arrhythmias cardiovascular cause caused cerebrovascular attack chemokines chronic circulating cognitive conditions contribute coronavirus disease COVID-19 Deep venous thrombosis Dementia disease donors edema endothelial Endothelium Evidence expression heart failure homeostasis impairment indicate infiltration Inflammatory cytokine intercellular Invasion manifestation Manifestations Myocardial infarction myocarditis nitric oxide patients with COVID-19 promoted Pulmonary embolism pulmonary fibrosis role SARS-CoV-2 stroke therapeutic therapy Thromboembolism thrombosis Venous Thromboembolism ventricular virus
[DOI] 10.14797/mdcvj.1044 PMC 바로가기 [Article Type] Review

Remdesivir; molecular and functional measures of mitochondrial safety

렘데시비르; 미토콘드리아 안전성의 분자 및 기능적 측정

Article

Published on 2021-12-152022-09-11
Journal: Toxicology and applied pharmacology [Category] 치료제,

[키워드] Alter antiviral drug antiviral drugs approved cause complexes Concentration copy number coronavirus coronavirus 2 COVID Culture cytotoxicity drug Efficiency expression functional Genome genomic HepG2 hospitalized patients Infection inhibiting inhibitor inhibitory activity interfere liver cell measure mechanism Mitochondria mitochondrial mitochondrial RNA molecular nuclear nucleoside observation Off-Target parameter polymerase prodrug Remdesivir respiratory capacity respiratory chain RNA polymerase RNA-dependent RNA polymerase SARS-CoV-2 Severe case severe cases shown subunit Toxicity viral replication Viral RNA viral RNA-dependent RNA polymerase
[DOI] 10.1016/j.taap.2021.115783 PMC 바로가기 [Article Type] Article

Innate Immunity as an Executor of the Programmed Death of Individual Organisms for the Benefit of the Entire Population

Review

Published on 2021-12-152022-10-29
Journal: International Journal of Molecular Sciences [Category] Coronavirus, SARS,

Facemask Usage Among People With Primary Ciliary Dyskinesia During the COVID-19 Pandemic: A Participatory Project

Observational Study

Published on 2021-12-152022-10-04
Journal: International Journal of Public Health [Category] MERS, SARS, 임상,

MRFGRO: a hybrid meta-heuristic feature selection method for screening COVID-19 using deep features

MRFGRO : 깊은 기능을 사용하여 Covid-19 스크리닝을위한 하이브리드 메타 허리 기능 선택 방법

Article

Published on 2021-12-152022-09-01
Journal: Scientific Reports [Category] 진단, 치료기술,

[키워드] Accuracy affected Algorithm Analysis approach both lungs cause Chain Reaction chest CT-scan CNN CNNs Computed tomography computer Computer science Convolutional neural networks COVID-19 COVID-19 diagnosis dataset datasets Diagnosis disease feature first stage foraging global pandemic globe Golden Ratio Health Organization Image analysis Infection Infectious diseases less Local lung Lung disease Lung diseases Lungs MONITOR parameter polymerase chain reaction Ratio Ray real-time reverse transcription-polymerase chain reaction respiratory Respiratory disease Reverse transcription-polymerase chain reaction RT-PCR Scientific data Software Spread stages subset upper respiratory tract WHO World Health Organization
[DOI] 10.1038/s41598-021-02731-z PMC 바로가기 [Article Type] Article

The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

Cardiovascular System & Vascular Biology

Published on 2021-12-152022-10-31
Journal: Clinical Science (London, England : 1979) [Category] COVID-19, SARS,

[키워드] ACE2 Activation acute respiratory syndrome alterations angiotensin converting enzyme 2 angiotensin-converting enzyme 2 antibody cause caused CD147 Cell cellular clinical response contributing to coronavirus COVID-19 death disease disrupt dysfunction elicited Endothelial cell events exposure to Extracellular Factor functional Hypothesis Implications in vitro induce infect infected patients Infection involved Ligand mechanism Microvascular damage Microvascular disease microvascular injury Migration mRNA neutralisation Patient pericyte Peripheral blood pro-apoptotic pro-inflammatory molecule Protein receptor recombinant S protein reduced rescued S protein SARS-CoV-2 secretion spike Spike protein stimulate Stress Support tested the cytokine storm the S protein the SARS-CoV-2 therapeutic variant Vascular wildtype
[DOI] 10.1042/CS20210735 PMC 바로가기 [Article Type] Cardiovascular System & Vascular Biology

Recapitulating Trafficking of Nucleosides Into the Active Site of Polymerases of RNA Viruses: The Challenge and the Prize

Medical Technology

Published on 2021-12-142022-11-01
Journal: Frontiers in Medical Technology [Category] COVID-19,

Public Emotional and Coping Responses to the COVID-19 Infodemic: A Review and Recommendations

Psychiatry

Published on 2021-12-142022-10-31
Journal: Frontiers in Psychiatry [Category] COVID-19,

Complement C5a and Clinical Markers as Predictors of COVID-19 Disease Severity and Mortality in a Multi-Ethnic Population

다민족 집단에서 COVID-19 질병 중증도 및 사망률의 예측 인자로서 C5A 및 임상 마커 보완

Immunology

Published on 2021-12-132022-08-31
Journal: Frontiers in Immunology [Category] SARS, 바이오마커,

[키워드] Accuracy acute kidney addition advance albumin allocation Anemia Asymptomatic Biomarker Biomarkers Blood blood count blood indices C-reactive protein C5a C5a anaphylatoxin cause CBC clinical Clinical severity Coagulation Cohort common Comorbidities complement complement component complete blood count coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients death in COVID-19 develop disease severity Electrolytes elevated Endothelial dysfunction ferritin Glucose help hepatocellular injury high risk higher risk Hypoalbuminemia identify IMPROVE Infection Inflammation interleukin interleukin-6 kidney kidney function parameter life-threatening liver lymphocyte Lymphocyte count lymphopenia marker Mild Mortality neutrophilic leukocytosis Non-survivors pandemic parameter parameters Patient patients physiological Population predict Predictive procalcitonin prognostic recruited resource routine test SARS-CoV-2 SARS-COV-2 infection severe disease severe symptom severe symptoms severity split product Stage statistically significant Stratification survival survival analysis survivor the disease thrombosis Treatment vital signs were measured WHO
[DOI] 10.3389/fimmu.2021.707159 PMC 바로가기 [Article Type] Immunology

Computational Insights Into the Effects of the R190K and N121Q Mutations on the SARS-CoV-2 Spike Complex With Biliverdin

Molecular Biosciences

Published on 2021-12-132022-10-31
Journal: Frontiers in Molecular Biosciences [Category] COVID-19,