Uptake of telehealth in Parkinson’s disease clinical care and research during the COVID-19 pandemicMini review Published on 2021-05-012022-10-05 Journal: Parkinsonism & Related Disorders [Category] 임상, [키워드] activity barrier Care clinical care Clinical practice clinical trial Clinical use clinician conducted coronavirus COVID-19 COVID-19 pandemic demographic data deviation disease ENhance evaluate fill out group impacted in-person visit Patient Patient care patients protocol provided remained Research responses Result synchronous technology telehealth Telemedicine uptake [DOI] 10.1016/j.parkreldis.2021.03.032 [Article Type] Mini review
Robust SARS-CoV-2-specific T cell immunity is maintained at 6 months following primary infection강력한 SARS-CoV-2-특이 T 세포 면역은 1차 감염 후 6개월 동안 유지됩니다.Article Published on 2021-05-012022-09-12 Journal: Nature Immunology [Category] Fulltext, SARS, 진단, [키워드] Analysis analyzed antibody CD4 cellular immunity characterized correlated correlation Critical cytokine expression disease Donor functional immune response Immunity Infection intracellular cytokine staining magnitude phenotype predominant Primary infection Protein Reinfection responses retained SARS-CoV-2 severity symptomatic infection T cell T cell response waning immunity [DOI] 10.1038/s41590-021-00902-8 PMC 바로가기 [Article Type] Article
Validation of a commercially available indirect assay for SARS-CoV-2 neutralising antibodies using a pseudotyped virus assay유사형 바이러스 분석을 사용한 SARS-CoV-2 중화 항체에 대한 상업적으로 이용 가능한 간접 분석의 검증Article Published on 2021-05-012022-09-10 Journal: The Journal of Infection [Category] Fulltext, SARS, 진단, 치료기술, 치료제, [키워드] anti-RBD assays cell lines demonstrated ELISA functional immune response Highlights human sera immune responses immunologically Linear regression measure neutralisation neutralisation assay neutralise neutralising neutralising antibody objective Patient positive correlation provide Pseudotyped virus RBD binding antibodies response responses responses against Result S protein SARS-CoV-2 SARS-CoV-2 neutralising antibody SARS-CoV-2 S serum sample serum samples spike target cell tested the RBD validation Viral viral infection was measured [DOI] 10.1016/j.jinf.2021.03.010 PMC 바로가기 [Article Type] Article
Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity헤마글루티닌 기능화 리포솜 백신은 배아 중심 및 여포 도우미 T 세포 면역을 강화합니다Article Published on 2021-05-012022-09-12 Journal: Advanced Healthcare Materials [Category] SARS, 진단, [키워드] Antigen B cell center draining lymph nodes driving effective vaccine elicit follicular follicular helper T cells Germinal Germinal center germinal centers helper helper T cell hemagglutinin highly pathogenic HIV immunization immunogen Influenza influenza vaccines Influenza virus life-threatening Liposome liposomes mice microfluidic mixers nanoparticle-based vaccines. pathogen Protective Protein provide public health reported responses Safe SARS-CoV-2 serum antibody Subunit vaccine subunit vaccines Toxicity Vaccine Vaccines virus [DOI] 10.1002/adhm.202002142 PMC 바로가기 [Article Type] Article
High-throughput detection of antibodies targeting the SARS-CoV-2 Spike in longitudinal convalescent plasma samples종적 회복기 혈장 샘플에서 SARS-CoV-2 스파이크를 표적으로 하는 항체의 고처리량 검출Clinical Trial Published on 2021-05-012022-09-11 Journal: Transfusion [Category] MERS, SARS, 임상, 진단, 치료기술, 치료제, [키워드] 293T acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibodies antibody Antibody responses approach cell line convalescent convalescent plasma coronavirus coronavirus disease Coronavirus disease 2019 Coronaviruses correlated COVID-19 deaths Decline detect develop domain donors expressing flow cytometry full-length SARS-CoV-2 glycoprotein help High-throughput screening Humoral response humoral responses infecting Infection information longitudinal analysis Longitudinal studies longitudinal study observation pandemic performed persistence plasma post-symptom onset RBD RBD domain RBD-specific antibodies RBD-specific antibody Receptor-binding domain reduce respiratory responses Result SARS-CoV-2 SARS-CoV-2 spike severe acute respiratory syndrome Coronavirus severity of COVID-19 shown specific antibodies spike spike glycoproteins Spike-specific antibody the RBD the receptor-binding domain the SARS-CoV-2 transfusion Viral viral entry virus [DOI] 10.1111/trf.16318 PMC 바로가기 [Article Type] Clinical Trial
Post-Acute COVID-19 Neurological Syndrome: A New Medical ChallengeReview Published on 2021-05-012022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] affected Assessing Brain brain damage cause challenge China clinical manifestation Complication Consensus coronavirus COVID-19 COVID-19 pandemic delirium Evidence feature group highly pathogenic include Infection Inflammation nerve damage Neurological symptom NEUROLOGY New new virus organ pandemic patients with COVID-19 post-scute COVID-19 neurological syndrome psychological Impact recent responses SARS-CoV-2 Severe COVID-19 Infection severe pneumonia stroke Symptom to define Wuhan [DOI] 10.3390/jcm10091947 PMC 바로가기 [Article Type] Review
Immune profiling of COVID-19: preliminary findings and implications for the pandemicCOVID-19의 면역 프로파일링: 팬데믹에 대한 예비 연구 결과 및 의미Review Published on 2021-05-012022-09-12 Journal: Journal for immunotherapy of cancer [Category] SARS, 진단, [키워드] acute infection adaptive Adaptive immunity antibody asymptomatic infection baseline cellular change clinical outcomes clinical symptom Course COVID-19 cross-reactive death disease disease severity help host immune system humoral immune Immune profile immune response Immunity implication infected individuals Infection Inflammation Inflammation mediators Innate interact majority other coronavirus outcome pandemic preliminary finding Research response responses SARS-CoV-2 subsequent T cell response understanding uninfected Vaccine development virus [DOI] 10.1136/jitc-2021-002550 PMC 바로가기 [Article Type] Review
OxCOVID19 Database, a multimodal data repository for better understanding the global impact of COVID-19Article Published on 2021-04-292022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] Analysis country COVID-19 COVID-19 pandemic curated database digital curation Effect Epidemiology facilitate Factor geographical regions Government granular Homo sapien Infectious disease Infectious diseases information Intervention National Oxford pandemic provide reduce Repository responses Sample SARS-CoV-2 virus Scientific data Spread technology variety [DOI] 10.1038/s41598-021-88481-4 PMC 바로가기 [Article Type] Article
Surveillance of the Second Wave of COVID-19 in Europe: Longitudinal Trend AnalysesOriginal Paper Published on 2021-04-282022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, MERS, [키워드] absence Albania Analysis Andorra approach Arellano-Bond estimator Austria average Belarus Belgium Bosnia and Herzegovina Bulgaria country Course COVID 7-day lag COVID transmission deceleration COVID transmission jerk COVID-19 COVID-19 case COVID-19 pandemic COVID-19 transmission Croatia cumulative Czech Republic death decrease Denmark dynamic panel data Estonia Europe Europe COVID Europe COVID surveillance system Europe econometrics Europe Public Health Surveillance Europe SARS-CoV-2 Europe surveillance metrics European European COVID transmission acceleration European COVID transmission speed Finland France generalized method of the moments Germany global COVID surveillance GMM Greece Greenland growth Health Hungary Iceland impacted Ireland Isle of Man Italy Latvia Liechtenstein Lithuania longitudinal Luxembourg measure Metrics Moldova Monaco Montenegro Netherlands New Norway objective outbreak pandemic performed persistence Poland Portugal positive Public public health rapid expansion responses Result resulting reversed risk Romania San Marino SARS-CoV-2 SARS-CoV-2 surveillance second second wave Serbia Slovakia Slovenia Spain Surveillance Sweden Switzerland Transmission trend Ukraine United Kingdom variable Vatican City Wave wave two [DOI] 10.2196/25695 PMC 바로가기 [Article Type] Original Paper
Neutralizing Antibody Responses After SARS-CoV-2 Infection in End-Stage Kidney Disease and Protection Against ReinfectionClinical Research Published on 2021-04-282022-10-04 Journal: Kidney International Reports [Category] 비임상, [키워드] absence Abstract acute respiratory syndrome Against anti-N IgG antibody Asymptomatic Asymptomatic disease baseline coronavirus COVID-19 detectable determine develop ELISA enzyme-linked immunosorbent ESKD evaluate evaluated functional Hemodialysis humoral immune response Humoral immunity IgG level immune response individual Infection infectious complication investigated Kidney disease median NAb Neutralization assay Neutralizing activity neutralizing antibody outcome Patient patients polymerase chain protection pseudotype renal Repeat response responses Result retained risk factor S1 subunit SARS-CoV-2 SARS-CoV-2 spike seroconvert seroconverted seroconverted patient serum sample susceptibility [DOI] 10.1016/j.ekir.2021.03.902 PMC 바로가기 [Article Type] Clinical Research