COVID-19: Um Novo Desafio para a Cardiopatia na GravidezEditorial Published on 2020-07-282022-10-28 Journal: Arquivos Brasileiros de Cardiologia [Category] COVID-19, SARS, [키워드] Coronavírus coronavirus COVID-19 COVID19 Fatores de Risco Gravidez Gravidez de Alto Risco Hipertensão/prevenção e controle Hypertension/prevention and control Morbidade morbidity Mortalidade Mortality Pandemia Pandemics Pneumonia Pregnancy Pregnancy, high-risk Risk factors Síndrome Respiratória Aguda Grave Severe acute respiratory syndrome [DOI] 10.36660/abc.20200511 PMC 바로가기 [Article Type] Editorial
A Review of Postmortem Findings in Patients With COVID-19Cardiology Published on 2020-07-282022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome advance affected article Autopsy biopsies cardiovascular caused coronavirus coronavirus disease coronavirus strain country COVID-19 COVID19 diagnose disease disease pathology eligible finding FIVE Health help hematologic hematology histopathological finding impacted information Injury Lungs mechanism MERS Morphological Multiple organ organ systems pandemic Postmortem postmortem pathological findings problem public health renal review selected significantly spread to syndrome the disease virus was used Wuhan, China [DOI] 10.7759/cureus.9438 PMC 바로가기 [Article Type] Cardiology
COVID-19-Induced Cytokine Release Syndrome Associated with Pulmonary Vein Thromboses, Atrial Cardiomyopathy, and Arterial Intima InflammationCase Report Published on 2020-07-262022-10-29 Journal: TH Open: Companion Journal to Thrombosis and Haemostasis [Category] COVID-19, [키워드] acute kidney failure acute respiratory distress ARDS arterial atria Atrial fibrillation autonomic Cardiomyopathy caused Coronavirus disease 2019 COVID-19 COVID19 Cytokine release syndrome death described elevated embolic events Evidence expression fibrillation ganglia Inflammatory Inflammatory cytokine interleukin-6 Intima involved knowledge Local manifestation MCP-1 monocyte chemoattractant protein-1 multiorgan failure Myocardium organ organ dysfunction pathology perivascular provide pulmonary Release SARS-CoV-2 shown sinus node stroke syndrome Vein vessel viral disease [DOI] 10.1055/s-0040-1716717 PMC 바로가기 [Article Type] Case Report
Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversionArticle Published on 2020-07-242022-10-04 Journal: Nature Communications [Category] 진단, [키워드] anti-SARS-CoV-2 antibody coronavirus disease COVID-19 COVID19 Crohn's disease cytokine cytokine inhibitor Epidemiology Gut healthy control Immune-mediated inflammatory disease incidence Inflammatory cytokines inflammatory disease inhibitor involved jak inhibitors joints observé Pathogenesis pathology Patient patients treated populations Prevalence PROTECT Protective receiving reduced response rheumatoid arthritis Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 Seroconversion severe COVID-19 treated Treatment viral infection [DOI] 10.1038/s41467-020-17703-6 PMC 바로가기 [Article Type] Article
Profiles of COVID-19 clinical trials in the Chinese Clinical Trial RegistryReview Published on 2020-07-222022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] adopted anti-viral drug Anti-viral drugs caused Characteristics Chinese clinical clinical study clinical trial clinical trials comprehensive analysis COVID-19 COVID-19 pandemic COVID19 Effect effective drug effort global public health Government help identify International Intervention outcome profile public health Registered registry resource significantly supported Traditional Chinese medicine Vaccine virus [DOI] 10.1080/22221751.2020.1791736 PMC 바로가기 [Article Type] Review
High neutralizing antibody titer in intensive care unit patients with COVID-19Research Article Published on 2020-07-202022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] accelerated Admission clinical factor confidence interval Coronavirus disease 2019 COVID-19 COVID-19 patient COVID19 detectable Disease progression disease severity eight Fever geometric Hong Kong ICU ICU patient individual individuals Infection intensive care median Mild Multivariate analysis nAb response NAb titer NAb titers neutralizing antibody Neutralizing antibody titer Non-COVID-19 non-ICU patient non-ICU patients Oxygen requirement Patient patients with COVID-19 Region required Respiratory failure response SARS-CoV-2 serum significantly significantly higher specimen Spread Stage suggested symptoms onset unlikely upper respiratory symptom [DOI] 10.1080/22221751.2020.1791738 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 Entry Receptor ACE2 Is Expressed on Very Small CD45 − Precursors of Hematopoietic and Endothelial Cells and in Response to Virus Spike Protein Activates the Nlrp3 InflammasomeArticle Published on 2020-07-202022-10-28 Journal: Stem cell reviews and reports [Category] COVID-19, MERS, [키워드] ACE2 ACE2 receptor activate Ang II CD133 CD34 CD45 Cell cell death cell lysis cells COVID19 Cytokine storm damaged described Effect endothelial entry receptor enzyme Express expressed functional Genes hematopoietic Hematopoietic stem cell hematopoietic stem cells human cells hyperactivate indicate induce infect Inflammasome Interaction murine NLRP3 inflammasome progenitor cell protease TMPRSS2 protective effect pyroptosis RAAS raise receptor response SARS-CoV-2 SARS-CoV2 shown spike Spike protein stem cell stem cells the SARS-CoV-2 these cell tissue transmembrane umbilical cord blood viral spike protein virus VSELs [DOI] 10.1007/s12015-020-10010-z PMC 바로가기 [Article Type] Article
Mesenchymal Stem Cells: A new front emerge in COVID19 treatment Mesenchymal Stem Cells therapy for SARS-CoV2 viral infectionArticle Published on 2020-07-152023-07-01 Journal: Cytotherapy [Category] SARS, [키워드] ALT, alanine aminotransferase Ang-1, Angiopoietin 1 AST, aspartate aminotransferase BDNF, Brain Derived Neurotrophic factor coronavirus COVID19 CRP, C-reactive protein CT Scan, Computerized Tomography Scan Cytokine storm Fio2, fraction of inspired oxygen GCSF, granulocyte colony stimulating factor ICAM, Intercellular Adhesion Molecule 1 IFN-γ, interferon gamma IL-1β, interleukin 1 beta IL-10, interleukin 10 IL-2, interleukin 2 IL-6, interleukin 6 IL-7, interleukin 7 immunomodulation LPS, lipopolysaccharide MCP-1, monocyte chemoattractant protein 1 Mesenchymal stem cells MHC-I, major histocompatibility complex class I MHC-II, major histocompatibility complex class II MIP-1α, Macrophage Inflammatory Proteins 1 alpha Pao2, partial pressure of oxygen PCT, Proximal Convoluted Tubule PDGF, platelet derived growth factor Pneumonia PSI, Pound per Square Inch RT-PCR, Reverse transcription polymerase chain reaction SAA, Specialized Adoption Agency SARS-CoV-2 TLR3, Toll like Receptors 3 TLR4, Toll like Receptors 4 TNF-α, tumor necrosis factor alpha VCAM, Vascular Cell Adhesion Protein 1 VEGF, Vascular endothelial growth factor [DOI] 10.1016/j.jcyt.2020.07.002 PMC 바로가기 [Article Type] Article
New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysisCorrespondence Published on 2020-07-152022-10-28 Journal: BMC Medicine [Category] COVID-19, SARS, [키워드] ACE2 acute respiratory syndrome age Analysis Angiotensin-converting enzyme 2 (ACE2) Cancer cardiovascular diseases caused conditions contribute coronavirus COVID-19 COVID-19 pandemic COVID19 DNA polymorphism effective expression Factor Genetic genetic susceptibility Health Host Human Human genetics Human genomes Hydroxychloroquine infected individuals interactions investigated locus male Mortality New offer patients polymorphism Population prevalent progressive disease proportion pulmonary condition Quantitative Risk factors SARS-CoV-2 selective suggested TMPRSS2 transmissibility of SARS-CoV-2 Treatment unique [DOI] 10.1186/s12916-020-01673-z PMC 바로가기 [Article Type] Correspondence
From the index case to global spread: the global mobility based modelling of the COVID-19 pandemic implies higher infection rate and lower detection ratio than current estimatesEpidemiology Published on 2020-07-102022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] 95% confidence interval addition Analytic parametrization Asymptomatic basic reproduction number characteristic Compliance Concordance conducted confirmation country COVID-19 cases COVID-19 pandemic COVID19 diagnosed Diagnosis effective effort epidemiological estimate FIVE Global COVID19 model help High-resolution index case infection rate Mild symptom Mobility mortality rate New York non-infectious number of infected outbreak outbreak modelling outcome overcome pandemic pandemic modelling parameter parameters pregnant women presenting presymptomatic Prevalence Probability random Research Result SARS-CoV-2 screening test selected severe symptom severe symptoms Spread the disease Transmissibility Transmission model Travel virus Wuhan, China [DOI] 10.7717/peerj.9548 PMC 바로가기 [Article Type] Epidemiology