The role of European health system characteristics in affecting Covid 19 lethality during the early days of the pandemicArticle Published on 2021-12-092022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] affecting Care cause caused Characteristics Chronic diseases contribute COVID-19 diffusion Epidemic Europe European Evidence Factor GDP Health Health care economics Health policy health system healthcare hospital ICU intensive care management Nurse Older outcome pandemic Practitioner random virus [DOI] 10.1038/s41598-021-03120-2 PMC 바로가기 [Article Type] Article
Antiviral Activity of the Rhamnolipids Mixture from the Antarctic Bacterium Pseudomonas gessardii M15 against Herpes Simplex Viruses and CoronavirusesArticle Published on 2021-12-082022-10-28 Journal: Pharmaceutics [Category] COVID-19, [키워드] activity addition Antarctic bacteria Antiviral antiviral action antiviral activity Antiviral effect Bacteria bacterium being cause Complete compounds Coronaviridae coronavirus Cytopathic effect demonstrated detectable displaying effective enveloped virus HCoV-229E HCoV-OC43 Health Herpe herpes Herpesviridae HSV-1 inactivation investigated less microbial microbial biosurfactants mixture Outbreaks produced Pseudomona Rhamnolipid rhamnolipids SARS-CoV-2 TEM treated Type virus was recorded [DOI] 10.3390/pharmaceutics13122121 PMC 바로가기 [Article Type] Article
SARS-CoV-2 and Streptococcus pneumoniae Coinfection in a Previously Healthy ChildCase Report Published on 2021-12-082022-10-31 Journal: Case Reports in Pediatrics [Category] COVID-19, [키워드] acute respiratory syndrome Bacterial cause caused Child Coinfection coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patient described healthy Infection Influenza Novel coronavirus pandemic Pediatric patients Pneumonia reported responsible SARS-CoV-2 Streptococcus pneumoniae viral respiratory viruses Wuhan, China [DOI] 10.1155/2021/8907944 PMC 바로가기 [Article Type] Case Report
Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48Research Article Published on 2021-12-082022-10-28 Journal: Science Advances [Category] COVID-19, [키워드] C15orf48 cause change conserved COVID-19 cytochrome Decline description disease severity elevated Evidence exchange expressed expression functions hallmark Immune-mediated inflammatory diseases in vitro Inflammation inflammatory disease inflammatory signal Macrophage macrophage activation macrophages metabolic disease mitochondrial Mitochondrial function molecular monocyte mRNA NDUFA4 occur oxygen pathogenic Pathologies proinflammatory provide rheumatoid arthritis severe coronavirus disease subunit Support syndrome synovial tissue macrophages transcript [DOI] 10.1126/sciadv.abl5182 PMC 바로가기 [Article Type] Research Article
Myocardial Injury Complicated by Systolic Dysfunction in a COVID-19-Positive DogCase Report Published on 2021-12-082022-10-28 Journal: Animals : an Open Access Journal from MDPI [Category] COVID-19, [키워드] acute respiratory syndrome affected canine cardiological Case report cause characterising Charle clinical picture Clinical sign closely resemble concerning conducted contribute coronavirus coronavirus disease COVID-19 described diagnosing Diagnosis diagnostic dilated cardiomyopathy phenotype disease manifestation Diseases dog dysfunction echocardiography epidemiological survey Human Infection infective King knowledge Local manifested molecular test Myocardial myocardial injury myocarditis pandemic performed Result SARS-CoV-2 SARS-COV-2 infection serological simple Spread supported susceptible Symptom Syncope systolic ventricular viral disease zoonotic origin [DOI] 10.3390/ani11123506 PMC 바로가기 [Article Type] Case Report
N-glycosylation profiles of the SARS-CoV-2 spike D614G mutant and its ancestral protein characterized by advanced mass spectrometryArticle Published on 2021-12-072022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] ACE2 binding acute respiratory syndrome cause change changed characterized conditions coronavirus COVID-19 D614G D614G substitution decrease diagnostic tests distribution glycan glycosylated glycosylation glycosylation site increase in Infectious diseases membrane mutant N-glycosylation profile Protein Proteins proteomics reduction in remained SARS-CoV-2 SARS-CoV-2 spike glycoprotein SARS-CoV-2 variant secreted proteins Spike protein the SARS-CoV-2 therapeutic drug Transmission Vaccines variant virus wild type [DOI] 10.1038/s41598-021-02904-w PMC 바로가기 [Article Type] Article
Possible Role of Accessory Proteins in the Viral Replication for the 20I/501Y.V1 (B.1.1.7) SARS CoV-2 VariantCommunication Published on 2021-12-072022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] 20I/501Y.V1 Accessory acute respiratory syndrome B.1 B.1.1.7 B.1.1.7 variant cause Coronavirus-2 demonstrated experimental evidence expression Hypothesis in viral Infectious virus maturation Next-generation sequencing nucleocapsid ORF6 ORF8 Replication reported required role RPKM SARS CoV-2 TCID50 The B.1.1.7 transcript transcriptional transcriptional response Transmissibility Transmission variant viral replication [DOI] 10.3390/pathogens10121586 PMC 바로가기 [Article Type] Communication
CD19+IgD+CD27- Naïve B Cells as Predictors of Humoral Response to COVID 19 mRNA Vaccination in Immunocompromised Patients면역 저하 환자에서 COVID 19 mRNA 백신 접종에 대한 체액 반응의 예측 인자로서의 CD19+IgD+CD27- 나이브 B 세포Clinical Trial Published on 2021-12-072022-09-12 Journal: Frontiers in Immunology [Category] SARS, 임상, 진단, [키워드] 95%CI Analysis analyzed anti-SARS-CoV-2 antibody Antibody Response B cells B-cell Cancer cause CD19 CD27 circulating comparable COVID 19 COVID-19 cut-off healthy control healthy controls hematologic Hematologic malignancy humoral identify IGD immunoassay Immunocompromised Immunocompromised patients immunodeficiencies immunodeficiency independent mRNA mRNA vaccine naïve B cell occurred Patient performed predictor RBD receiver operating characteristic response second vaccination subset the receptor-binding domain trimeric S protein vaccination vaccination against COVID-19 [DOI] 10.3389/fimmu.2021.803742 PMC 바로가기 [Article Type] Clinical Trial
Autoimmune Encephalitis After SARS-CoV-2 Infection: Case Frequency, Findings, and OutcomesSARS-CoV-2 감염 후 자가면역 뇌염: 사례 빈도, 소견 및 결과Article Published on 2021-12-072022-09-12 Journal: Neurology [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome age application arising assist Ataxia Autoimmune Autoimmune encephalitis case sery cause chemiluminescence clinical presentation clinical record Cohort cohort patient coronavirus coronavirus disease COVID-19 COVID-19 illness COVID-19 pandemic CSF delirium Department determine diagnosed diagnoses diagnostic Diagnostic Criteria died drug Encephalitis Encephalopathy feature food Frequency IgG immune Immunoglobulin Infection Laboratory Mayo Clinic median symptom memory MRI neurologic NEUROLOGY Non-COVID-19 one patient overlapped PASC Patient Pneumonia positive Postinfectious problems reported representing Research residual SARS CoV-2 SARS-CoV-2 SARS-CoV-2 antibody Seizure sera spike glycoprotein tested the SARS-CoV-2 therapy total antibody viral particle women [DOI] 10.1212/WNL.0000000000012931 PMC 바로가기 [Article Type] Article
Case Report: Self-Administration of Omalizumab in an Adolescent With Severe Asthma During SARS-CoV-2 InfectionPediatrics Published on 2021-12-062022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] acute respiratory syndrome Adolescent affected Allergic asthma allergy Asthma cause characteristic children Clinical practice coronavirus coronavirus disease COVID-19 Frequency healthcare Hospitalization implication increased risk Infection initiative knowledge management monoclonal antibody omalizumab other treatments pandemic Patient pediatrics physician reduction in reported Research respiratory infection risk SARS-CoV-2 SARS-COV-2 infection severity switching Therapies therapy treated Treatment [DOI] 10.3389/fped.2021.675281 PMC 바로가기 [Article Type] Pediatrics