sera – Page 64 – Communicable Diseases Research

Clinical correlates of anti-SARS-CoV-2 antibody profiles in Spanish COVID-19 patients from a high incidence region

발병률이 높은 지역의 스페인 COVID-19 환자에서 항 SARS-CoV-2 항체 프로필의 임상 상관 관계

Article

Published on 2021-02-232022-09-01
Journal: Scientific Reports [Category] MERS, 진단, 치료기술, 치료법,

In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19

COVID-19의 혈청학적 진단을 위한 ELISA에서 SARS-CoV-2 특이적 B-세포 에피토프의 실리코 검출 및 검증

Article

Published on 2021-02-222022-09-10
Journal: Scientific Reports [Category] MERS, 진단, 치료기술,

[키워드] accelerate Antigen B-cell epitope Candidates Computational methods conducted COVID-19 database diagnosis of COVID-19 diagnostics disagreement ELISA ELISA plate Emerging infectious diseases Epidemiology epitope Epitopes FIVE fragment of help highest Inconclusive Infection Infectious disease Infectious diseases mixing N-terminal noise ratio nucleoprotein pathogen patients with SARS-CoV-2 plasma predict Protein Protein sequence analyses Rapid Receptor-binding domain Result RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 protein SARS-CoV-2 proteins sensitivity Sensitivity and specificity sequence sera serodiagnostic serological signal-to-noise ratio specificity Spike protein Spread structural biology the receptor-binding domain the spike protein viral infection
[DOI] 10.1038/s41598-021-83730-y PMC 바로가기 [Article Type] Article

Flow cytometry multiplexed method for the detection of neutralizing human antibodies to the native SARS‐CoV‐2 spike protein

천연 SARS-CoV-2 스파이크 단백질에 대한 중화 인간 항체 검출을 위한 유동 세포 계측법 다중화 방법

Article

Published on 2021-02-172022-09-11
Journal: EMBO Molecular Medicine [Category] MERS, SARS, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus antibody blood donor Blood donors classification coding sequence COVID‐19 cytometer Cytometry detect EGFR example expresse expressed Flow flow cytometry fluorescence intensities fluorescence intensity human population immune Immunoglobulin immunoglobulins immunology individual Infection method Methods & Resources Microbiology, Virology & Host Pathogen Interaction Neutralizing Neutralizing activity outbreak pandemic PCR Protective Protein Quantitative repeated respiratory S protein SARS‐CoV‐2 SARS‐CoV‐2 separated sequence sera serological test Serological tests seropositive individual seropositive individuals Seropositivity severe acute respiratory syndrome Coronavirus Spike protein T cell T‐cell
[DOI] 10.15252/emmm.202013549 PMC 바로가기 [Article Type] Article

Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera

표준화된 바이러스 중화 분석을 통해 SARS-CoV-2에 대한 절대 중화 역가를 정량화하면 COVID-19 혈청의 교차 코호트 비교가 가능합니다

Research Article

Published on 2021-02-162022-09-10
Journal: mBio [Category] MERS, 유전자 메커니즘, 진단,

[키워드] 293T ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody biosafety level Biosafety Level 3 BSL2 BSL3 clone cohorts Combination conditions convalescent-phase plasma coronavirus coronavirus disease Coronavirus disease 2019 CoV2pp COVID-19 develop Efficacy effort ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay Express G glycoprotein generate group highlight identify independent inhibit inhibitory concentration intergroup comparison intergroup comparisons level 3 limit limitations Live virus myriad NAbs neutralization neutralization potency Neutralizing antibodies neutralizing antibody Neutralizing titer overcome pandemic Particle Patient plasma positive correlation Postinfection produced pseudotyped Renilla luciferase gene respiratory SARS-CoV-2 Screen sera severe acute respiratory syndrome Coronavirus spike glycoprotein stomatitis Support therapy titer TMPRSS2 Vaccine Variability vesicular stomatitis vesicular stomatitis virus Viral viral entry viral neutralization assay virus neutralization assay VSVΔG
[DOI] 10.1128/mBio.02492-20 PMC 바로가기 [Article Type] Research Article

The Road towards Polyclonal Anti-SARS-CoV-2 Immunoglobulins (Hyperimmune Serum) for Passive Immunization in COVID-19

Communication

Published on 2021-02-152022-10-29
Journal: International Review of Cell and Molecular Biology [Category] COVID-19,

Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice

Report

Published on 2021-02-122022-10-28
Journal: Science (New York, N.y.) [Category] COVID-19, Fulltext, MERS, 조류인플루엔자,

[키워드] acute respiratory syndrome antibody Antigen bat Betacoronavirus betacoronaviruses bind binding caused convalescent coronavirus COVID-19 cross-reactive cross-reactive immune response disease displaying domain eight elicit elicited Fighting global pandemic Heterologous highlight host cell receptor Human humans immunization immunized mice mosaic neutralization neutralized neutralizing antibody responses Particle plasmas priming PROTECT protection Protein provide pseudotyped RBD RBDs Receptor binding domain recognizing responses resulting SARS-CoV-2 SARS-CoV-2 RBD Science sera strain Strains the SARS-CoV-2 thought threat virus Zoonotic coronavirus zoonotic coronaviruses
[DOI] 10.1126/science.abf6840 PMC 바로가기 [Article Type] Report

VOC 202012/01 Variant Is Effectively Neutralized by Antibodies Produced by Patients Infected before Its Diffusion in Italy

VOC 202012/01 변종 이탈리아에서 확산되기 전에 감염된 환자가 생산한 항체에 의해 효과적으로 중화

Communication

Published on 2021-02-112022-09-01
Journal: Viruses [Category] MERS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody appearance Apulia B.1.1.7 caused circulating coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Donor English evaluate expected health emergency Intervention Italy Lineage lineage B.1 Lineage B.1.1.7 Mutation mutations Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing titer occur pandemic Patient produced Region respiratory SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 VOC 202012/01 variant sera severe acute respiratory syndrome Coronavirus strain subject tested These data United Kingdom variant variants virus viruses VOC 202012/01
[DOI] 10.3390/v13020276 PMC 바로가기 [Article Type] Communication

Serological Test to Determine Exposure to SARS-CoV-2: ELISA Based on the Receptor-Binding Domain of the Spike Protein (S-RBD N318-V510 ) Expressed in Escherichia coli

Communication

Published on 2021-02-102022-10-31
Journal: Diagnostics [Category] COVID-19,

Evidence for SARS-CoV-2 related coronaviruses circulating in bats and pangolins in Southeast Asia

Article

Published on 2021-02-092022-10-29
Journal: Nature Communications [Category] COVID-19, MERS,

Neutralization of SARS-CoV-2 spike 69/70 deletion, E484K and N501Y variants by BNT162b2 vaccine-elicited sera

Research

Published on 2021-02-082022-10-05
Journal: Nature Medicine [Category] SARS, 변종,

[키워드] acute respiratory syndrome African BNT162b2 coronavirus doses E484K Effect elicited geometric mean titer GMT GMTs human sera mutant virus Mutation N501Y neutralization parental SARS-CoV-2 SARS-CoV-2 spike sera South spike mutation United Kingdom variant virus
[DOI] 10.1038/s41591-021-01270-4 [Article Type] Research