Short-term outcomes of a COVID-adapted triage pathway for colorectal cancer detection결장직장암 진단을 위한 COVID-adapted triage pathway의 단기 결과Article Published on 2021-07-012022-09-11 Journal: Colorectal disease : the official journal of the A [Category] SARS, 진단, 치료기술, [키워드] adverse effect adverse effects Cancer cancer diagnosis cancers Clinical data collected Colonoscopy Colorectal cancer coronavirus COVID-19 declined demographic Demographic and clinical data described detect detection rate Diagnosis diagnostic diagnostic services disease eight endoscopy expected faecal immunochemical tests Frequency immunochemical impacted initial measure median age mitigate MOST outcome outpatient clinic pandemic pathology pathway Patient patients primary care qFIT Quantitative reducing reduction in risk Seven subsequent Symptom the mean Triage women [DOI] 10.1111/codi.15618 PMC 바로가기 [Article Type] Article
The multidimensional prognostic index (MPI) for the prognostic stratification of older inpatients with COVID-19: A multicenter prospective observational cohort studyObservational Study Published on 2021-07-012022-10-05 Journal: Archives of gerontology and geriatrics [Category] SARS, 임상, [키워드] 95% confidence interval Accuracy Admission affected Area association AUC calculated Care CIs clinical decision Comprehensive Comprehensive geriatric assessment COVID-19 COVID-19 infection COVID-19 research Curve domain eight enrolled evaluate females frailty hazard ratio higher risk hospital Hospitalized HRs ICU ICU admission in-hospital mortality Inpatient Inpatients intensive care intensive care unit Italian less LOS Mortality MPI multicenter multidimensional Multidimensional prognostic index multivariable multivariable analysis NIV non-invasive ventilation not significant Older older patient Participants predict Prognosis prognostic prospective observational cohort regression analysis SARS-COV-2 infection Stratification three group Topic was used with COVID-19 [DOI] 10.1016/j.archger.2021.104415 PMC 바로가기 [Article Type] Observational Study
In-silico screening for identification of potential inhibitors against SARS-CoV-2 transmembrane serine protease 2 (TMPRSS2)SARS-CoV-2 막횡단 세린 프로테아제 2(TMPRSS2)에 대한 잠재적 억제제 식별을 위한 인실리코 스크리닝Article Published on 2021-07-012022-09-11 Journal: European journal of pharmaceutical sciences : offi [Category] SARS, 신약개발, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 binding energy binding free energy bridge calculated calculation China complex Compound condition coronavirus COVID COVID-19 docking downloaded drug drug repositioning eight Emergency form free energy highest homology human cell hydrogen Hydrogen bond hydrophobic hydrophobic interactions infected patients inhibitor Interaction Mechanics Medicine Medicines MM/PBSA molecular docking Molecular mechanics pandemic performed Physicochemical properties Protein protein structure protein-ligand reducing Research residues respiratory infection responsible salt Salt Bridge SARS-CoV-2 SARS-CoV-2 virus screened Serine serine protease Spread stability the SARS-CoV-2 virus TMPRSS2 TMPRSS2 protein transmembrane region transmembrane serine protease transmembrane serine protease 2 Transmissibility viral entry Virtual screening virus were used Wuhan Zinc ZINC database [DOI] 10.1016/j.ejps.2021.105820 PMC 바로가기 [Article Type] Article
The effect of tocilizumab on COVID-19 patient mortality: A systematic review and meta-analysis of randomized controlled trials코로나19 환자 사망률에 대한 토실리주맙의 효과: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-07-012022-09-12 Journal: International immunopharmacology [Category] SARS, 임상, 진단, [키워드] 28-day mortality 95% CI addition Admission AEs assigned benefit clinical Clinical efficacy Cochrane Library control group control groups COVID-19 COVID-19 patient Efficacy and safety eight enrolled Enrollment help ICU ICU admission Infection initial intensive care mechanical ventilation Meta-analysis Mortality no significant difference Patient patients with COVID-19 Placebo Primary outcome randomization Randomized controlled trial RCT RCTs receiving reduce registry risk Safe SARS-CoV-2 searched serious AE Standard of care subgroup analysis survival systematic review Tocilizumab Treatment treatment group treatment-emergent adverse event two group WHO [DOI] 10.1016/j.intimp.2021.107602 PMC 바로가기 [Article Type] Meta-Analysis
Benchmarking of eight recurrent neural network variants for breath phase and adventitious sound detection on a self-developed open-access lung sound database—HF_Lung_V1자체 개발 된 오픈 액세스 폐 사운드 데이터베이스에서 호흡 단계 및 우발적 사운드 감지를위한 8 개의 반복 신경 네트워크 변형 벤치마킹 -HF_LUNG_V1Research Article Published on 2021-07-012022-09-10 Journal: PLoS ONE [Category] MERS, 변종, 진단, [키워드] Accuracy addition adventitious sound Algorithm Analysis automated Benchmarking bidirectional breath CAS characteristic CNN conducted Convolutional neural network coronavirus coronavirus disease database defined Disease progression eight exhibited lung memory MONITOR receiver receiver operating characteristic required respiratory rhonchus robust Short-Term Memory stridor variant wheeze [DOI] 10.1371/journal.pone.0254134 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 antibody kinetics eight months from COVID-19 onset: Persistence of spike antibodies but loss of neutralizing antibodies in 24% of convalescent plasma donorsSARS-CoV-2 항체 역학 COVID-19 발병 후 8개월: 회복기 혈장 공여자의 24%에서 스파이크 항체는 지속되지만 중화 항체 손실Clinical Trial Published on 2021-07-012022-09-11 Journal: European journal of internal medicine [Category] SARS, 임상, 진단, 치료기술, 치료법, [키워드] Analysis anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibodies antibody Antibody Response Antibody responses Antigen antigens Characteristics contraction convalescent plasma COVID-19 decrease Donor eight faster Follow-up Hospitalization human immune response Immunity intervals linear median monitoring Multivariate analysis multivariate regression analysis neutralization ability Neutralizing Neutralizing antibodies neutralizing antibody nucleocapsid Older age participated Patient persistence Phase 2 Phase 2 study random-effect regression analysis response Result SARS-CoV-2 SARS-CoV-2 antibody spike symptom onset symptoms onset tested Vaccination strategies Vaccine [DOI] 10.1016/j.ejim.2021.05.010 PMC 바로가기 [Article Type] Clinical Trial
Ophthalmology-focused publications and findings on COVID-19: A systematic reviewCOVID-19에 대한 안과 중심 출판물 및 연구 결과: 체계적인 검토Meta-Analysis Published on 2021-07-012022-09-11 Journal: European Journal of Ophthalmology [Category] SARS, 치료기술, [키워드] America article articles China condition conditions Conjunctival swab conjunctival swabs conjunctivitis country COVID-19 COVID-19 illness COVID-19 infection COVID-19 infections COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 research COVID-19 transmission Cross-sectional studies cross-sectional study database Deceased disease manifestation eight Evidence FIVE India initial Italy manifestation Manifestations Meta-analysis Nasopharyngeal swab nasopharyngeal swabs occur ocular ocular symptoms Patient Prevalence produced publications reported Retina RNA Symptom Symptoms systematic review Transmission United Kingdom United State United States Viral RNA [DOI] 10.1177/1120672121992949 PMC 바로가기 [Article Type] Meta-Analysis
Timing and causes of death in severe COVID-19 patientsObservational Study Published on 2021-06-302022-10-04 Journal: Critical Care [Category] MERS, SARS, 임상, [키워드] accounted Analysis cause Causes of death COVID-19 death deaths eight event fibrosis French hospitals ICU ICU admission intensive care intensive care unit IQR majority median time medical records MODS Mortality multicenter observational study multiple organ dysfunction occurred Patient patients died PCR-confirmed performed previous study provided refractory reported Respiratory failure responsible Result Retrospective study SARS-CoV-2 SARS-COV-2 infection secondary Secondary infection Seven severe COVID-19 severe COVID-19 patient syndrome venous Ventilator-associated pneumonia [DOI] 10.1186/s13054-021-03639-w PMC 바로가기 [Article Type] Observational Study
Chronology of COVID-19 Symptoms in Very Old Patients: Study of a Hospital OutbreakArticle Published on 2021-06-302022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Atypical symptoms chronic condition Cohort controls COVID-19 COVID-19 outbreak defined delirium Diagnosis diagnosis of COVID-19 distribution early diagnosis eight Fever first symptom FIVE Frequency Gastrointestinal symptom Hospitalized Inpatient IQR majority median Neurological symptom older patient older patients outbreak Patient patients positive patients proportion recorded rehabilitation respiratory symptom Symptom Symptoms symptoms of COVID-19 temporal pattern the disease typical symptom were infected [DOI] 10.3390/jcm10132962 PMC 바로가기 [Article Type] Article
A single center evaluation of applicant experiences in virtual interviews across eight internal medicine subspecialty fellowship programsResearch Article Published on 2021-06-302022-10-29 Journal: Medical Education Online [Category] Coronavirus, SARS, [키워드] Area clinical experience conducted COVID-19 COVID-19 pandemic Culture eight evaluate fatigue fellowship interviews indicated information MOST Prevent questionnaire remote interviews Research San Francisco single center survey University of California Virtual interview [DOI] 10.1080/10872981.2021.1946237 PMC 바로가기 [Article Type] Research Article