Neutralization Assessments Reveal High Cardiothoracic Ratio and Old Age as Independent Predictors of Low Neutralizing Antibody Titers in Hemodialysis Patients Receiving a Single Dose of COVID-19 VaccineArticle Published on 2022-01-072022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] acute respiratory syndrome age antibody applied assessment ChAdOx1 clinical response Cohort coronavirus COVID-19 COVID-19 vaccine domain Effectiveness elicited enrolled enzyme-linked immunosorbent first dose GMT healthy control healthy subject Hemodialysis humoral International mRNA-1273 Multiple linear regression NAb neutralization titer Neutralizing antibodies neutralizing antibody Patient patients predict predictor quantification Ratio receiving regression analysis SARS-CoV-2 single dose single-center study the SARS-CoV-2 titer viral spike protein [DOI] 10.3390/jpm12010068 PMC 바로가기 [Article Type] Article
Serological responses to COVID-19 Comirnaty booster vaccine, London, United Kingdom, September to December 2021Rapid Communication Published on 2022-01-062022-10-31 Journal: Eurosurveillance [Category] COVID-19, SARS, [키워드] antibody AstraZeneca, Comirnaty, Vaxzevria Booster vaccine collected COVID-19 COVID-Vaccine GMT Immunity London participant peaked Pfizer response second dose serum sample Spike protein United Kingdom vaccination Vaccine [DOI] 10.2807/1560-7917.ES.2022.27.1.2101114 PMC 바로가기 [Article Type] Rapid Communication
Sequential immunization with SARS-CoV-2 RBD vaccine induces potent and broad neutralization against variants in miceSARS-COV-2 RBD 백신과의 순차적 면역화는 마우스의 변이체에 대한 강력하고 광범위한 중화를 유도한다.Short Report Published on 2022-01-042022-09-01 Journal: Virology Journal [Category] 변종, 진단, [키워드] A.23.1 addition Alpha Beta booster dose booster vaccination Booster vaccine booster vaccines Broadly neutralizing antibody caused COVID-19 pandemic Delta dose evaluated GMT GMTs Heterologous immunization immunized mice immunogenicity Inactivated vaccine Inactivated Vaccines induce Iota mice mutant Mutant RBD vaccine NAb NAbs neutralization Neutralizing antibodies Neutralizing antibody response public health RBD SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 variant SARS-CoV-2 variants Sequential immunization significantly supplementary material tested These data Vaccine variant variants wild-type [DOI] 10.1186/s12985-021-01737-3 PMC 바로가기 [Article Type] Short Report
Immunogenicity of a Heterologous Prime-Boost COVID-19 Vaccination with mRNA and Inactivated Virus Vaccines Compared with Homologous Vaccination Strategy against SARS-CoV-2 VariantsArticle Published on 2022-01-032022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] 95% CI adverse event blood sample BNT162b2 collected comparable CoronaVac COVID-19 D614G declined Delta variants dose Effectiveness evaluated geometric mean titre GMT group groups heterologous vaccination heterologous vaccine homologous immunogenicity Live virus microneutralization mRNA naïve Neutralization antibody Neutralizing activity neutralizing antibody participant recruited reduced Safe SARS-CoV-2 SARS-CoV-2 variant severe adverse events Strategy the antibody response the mean the SARS-CoV-2 the vaccine Vaccination strategy Vaccine vaccine immunogenicity Vaccines variant variants virus waned wild-type [DOI] 10.3390/vaccines10010072 PMC 바로가기 [Article Type] Article
Neutralization of alpha, gamma, and D614G SARS-CoV-2 variants by CoronaVac vaccine-induced antibodiesCoronaVac 백신 유도 항체에 의한 알파, 감마 및 D614G SARS-CoV-2 변이체 중화Article Published on 2022-01-012022-09-11 Journal: Journal of medical virology [Category] SARS, 변종, 진단, 치료기술, 치료제, [키워드] Alpha analyzed antibody collected CoronaVac CoronaVac vaccine Cytopathic effect D614G develop dose Effective strategies effective strategy efficient elicited generate genomic Genomic surveillance geometric mean geometric mean titer GMT help immune response inactivated individual Mutation neutralization neutralization potency Neutralizing Neutralizing antibodies plasma plasma samples reduction SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants second dose Surveillance vaccination Vaccine vaccine-induced antibody variant variants variants of SARS-CoV-2 Vero E6 Vero E6 cell VERO E6 cells Viral viral variant Viral variants [DOI] 10.1002/jmv.27310 PMC 바로가기 [Article Type] Article
Safety and immunogenicity of inactivated SARS-CoV-2 vaccine in high-risk occupational population: a randomized, parallel, controlled clinical trial고위험 직업군에서 비활성화된 SARS-CoV-2 백신의 안전성 및 면역원성: 무작위, 병렬, 대조 임상 시험Randomized Controlled Trial Published on 2021-12-222022-09-12 Journal: Infectious Diseases of Poverty [Category] Coronavirus, SARS, 임상, 진단, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus Adverse reaction Adverse reactions Analysis ANOVA antibody assigned baseline Chi-square China Chinese city clinical collected Controlled clinical trial Controlled trial coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Data analysis determine dose Endpoint geometric mean geometric mean titer GMT health-care system High-risk occupational population immunization immunogenicity inactivated Inactivated SARS-CoV-2 vaccine Infection injection Injections intention-to-treat ITT live SARS-CoV-2 Logistic regression analysis Mild neutralization Neutralizing antibodies neutralizing antibody participant primary immunogenicity randomization Randomized Randomized controlled trial Randomly receive regimen registry reported Result resulting Safety SARS-CoV-2 SARS-CoV-2 neutralizing antibody SARS-CoV-2 vaccine second dose Seroconversion seroconversion rate seroconversion rates Serum neutralizing antibody severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly significantly lower supplementary material the vaccine three groups Trial vaccination variance was performed were used [DOI] 10.1186/s40249-021-00924-2 PMC 바로가기 [Article Type] Randomized Controlled Trial
The Fitness Barometer: A Best Practice Example for Monitoring Motor Performance With Pooled Data Collected From PractitionersPublic Health Published on 2021-12-102022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] added age Analysis analysis of variance anonymously assessment barometer BMI children conducted COVID-19 pandemic determine example fitness Frequency Germany GMT group Health independent information Intervention mean value monitoring motor obese performance physical fitness Practice Practitioner question raw data reached resource Result significant difference Specific statistical analyses Test tested variety was collected Youth [DOI] 10.3389/fpubh.2021.720589 PMC 바로가기 [Article Type] Public Health
Antibody Response of BNT162b2 and CoronaVac Platforms in Recovered Individuals Previously Infected by COVID-19 against SARS-CoV-2 Wild Type and Delta VariantArticle Published on 2021-12-072022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] 95% CI 95% confidence interval Affect antibody response against BNT162b2 BNT162b2 vaccine boost booster booster dose CoronaVac COVID-19 Delta delta variant Delta variants dose geometric mean titre GMT group groups immune response increase increase in Increases individual Live virus mRNA vaccine naïve subject Neutralization assay Neutralizing activity neutralizing antibody no difference of BNT162b2 Patient receiving recovered recovered patient recruited reduced response SARS-CoV-2 sera significantly subjects the SARS-CoV-2 Type Vaccinating vaccination Vaccine vaccine platform Vaccines virus was determined wild-type [DOI] 10.3390/vaccines9121442 PMC 바로가기 [Article Type] Article
Randomized, Double-Blinded, Placebo-Controlled Phase 2 Trial of an Inactivated Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine in Healthy Adults건강한 성인을 대상으로 한 비활성화된 중증 급성 호흡기 증후군 코로나바이러스 2 백신에 대한 무작위, 이중 맹검, 위약 대조 2상 시험Clinical Trial Published on 2021-12-062022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 임상, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adverse reaction Adverse reactions anti-N antibodies anti-N antibody anti-S antibody clinical Controlled trial coronavirus coronavirus 2 dose double-blinded enrolled evaluated geometric mean geometric mean titer geometric mean titers GMT GMTs groups HD group healthy High dose immunization immunogenicity inactivated Inactivated SARS-CoV-2 vaccine medium dose neutralizing antibody Phase 2 phase 2 trial Randomized respiratory Safety safety analysis SARS-CoV-2 SARS-CoV-2 vaccine Serious Adverse Event Serious Adverse Events seroconversion rate seroconversion rates study period subject the vaccine Trial Vaccine [DOI] 10.1093/cid/ciaa1703 PMC 바로가기 [Article Type] Clinical Trial
The Impact of Age Difference on the Efficacy and Safety of COVID-19 Vaccines: A Systematic Review and Meta-Analysis연령 차이가 COVID-19 백신의 효능 및 안전성에 미치는 영향: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-12-062022-09-12 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] 95% CI Adults adverse event AEs age articles cause COVID-19 COVID-19 vaccine COVID-19 vaccines difference double-blind Effectiveness Efficacy and safety Egger’s test eligible evaluate Fever FIVE geometric mean titer GMT group immune immunosenescence Impact incidence Local local AE Meta-analysis objective Older Pain primary endpoint randomized-controlled trials (RCT) Rash Result review risk Safety scoring system SMD systemic AE systemic AEs tolerable Tolerance Vaccine virus was related was used with COVID-19 [DOI] 10.3389/fimmu.2021.758294 PMC 바로가기 [Article Type] Meta-Analysis