In silico studies on the comparative characterization of the interactions of SARS-CoV-2 spike glycoprotein with ACE-2 receptor homologs and human TLRsComparative Study Published on 2020-10-012023-07-06 Journal: Journal of medical virology [Category] SARS, [키워드] ACE-2 receptor human TLRs Phylogeny SARS-CoV-2 spike glycoprotein therapeutic intervention. [DOI] 10.1002/jmv.25987 PMC 바로가기 [Article Type] Comparative Study
Plants-Derived Biomolecules as Potent Antiviral Phytomedicines: New Insights on Ethnobotanical Evidences against CoronavirusesReview Published on 2020-09-212022-10-28 Journal: Plants [Category] COVID-19, [키워드] 3CLpro ACE-2 receptor Analysis Antiviral antiviral activity Antiviral compound antiviral property bioactive compounds Biomolecule Combination Compound coronavirus Coronaviruses correlation COVID-19 Critical develop drugs effective Efficacy ethnobotany Evidence human diseases increased mortality insight medicinal plant MERS-CoV metabolites natural products New pandemic disease Phytomedicine plant plants potent protocol researcher Safe SARS-CoV SARS-CoV-1 SARS-COV-2 infection targets therapeutic therapeutic agent Vaccine Viral protein [DOI] 10.3390/plants9091244 PMC 바로가기 [Article Type] Review
Pathophysiology and treatment strategies for COVID-19Review Published on 2020-09-152022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, SARS, [키워드] 2019 novel coronavirus ACE-2 receptor caused coronavirus COVID-19 COVID-19 case death disease Health hospital outbreak pandemic pathophysiology Potential treatment Receptor binding protein respiratory SARS-CoV-2 the SARS-CoV-2 Transmission Treatment treatment strategy viral inhibitor [DOI] 10.1186/s12967-020-02520-8 PMC 바로가기 [Article Type] Review
Characteristics and outcomes of diabetic patients infected by the SARS-CoV-2Case Study Published on 2020-09-082022-10-28 Journal: The Pan African Medical Journal [Category] COVID-19, MERS, SARS, [키워드] ACE-2 receptor Admission association blood pressure C-reactive protein Characteristics Clinical severity Clinical sign Clinical signs co-morbidity Comorbidity Complication complications COVID-19 COVID-19 patients death death rates demographic characteristics Demographic factors develop diabete diabetes diabetic patient Diseases ferritin form high risk hyper inflammation identify Infection intensive care Interaction lactic dehydrogenase mechanical ventilation morbidity and mortality not significant Older outcome outcomes Oxygen therapy patients patients with COVID-19 procalcitonin required retrospective risk risk factor SARS-CoV-2 severity the disease the patient the SARS-CoV-2 thromboembolic complication Treatment weight with COVID-19 [DOI] 10.11604/pamj.2020.37.32.25192 PMC 바로가기 [Article Type] Case Study
Medicinal Plants as Sources of Active Molecules Against COVID-19Pharmacology Published on 2020-08-072022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] ACE-2 receptor ACE2 addition Against anti-SARS-CoV-2 Combination conducted coronavirus 2 Coronavirus disease 2019 (COVID-19) country COVID-19 COVID-19 infection COVID-19 outbreak deaths drug drugs effective vaccine Google Scholar herbal medicine human cells infect infected patients Infection inhibit mechanism Medicine molecule natural products Novel coronavirus offer pandemic plant plants Prevent Proteases Protein purified recent finding required Research respiratory responsible SARS-CoV-2 serine protease severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) shown Source specific treatment Structure tested the SARS-CoV-2 the WHO therapeutic effect Therapeutic molecule treat virus replication website WHO [DOI] 10.3389/fphar.2020.01189 PMC 바로가기 [Article Type] Pharmacology
Convalescent plasma in Covid-19: Possible mechanisms of actionArticle Published on 2020-05-052023-06-14 Journal: Autoimmunity reviews [Category] MERS, SARS, [키워드] 2019-nCoV, 2019 novel coronavirus ACE-2 receptor ACE-2, Angiotensin converting enzyme-2 ADE, Antibody-dependent enhancement BAFF, B cell–activating factor BCR, B-cell receptor convalescent plasma coronavirus COVID-19 COVID-19, Coronavirus disease 2019 CP, convalescent plasma Cytokines DCs, dendritic cells E, Envelope HIV, Human immunodeficiency virus ICU, Intensive care unit IGG, immunoglobulin g IGM, immunoglobulin m Intravenous immunoglobulins IVIG, intravenous immunoglobulin M, membrane MERS-CoV, MERS coronavirus MERS, Middle East respiratory syndrome N, nucleoprotein NAbs, neutralizing antibodies NAT, Nucleic acid test Neutralizing antibodies S1-RBD, Spike1-receptor binding protein SARS-CoV-2 SARS-CoV, SARS coronavirus. SARS, severe acute respiratory syndrome coronavirus [DOI] 10.1016/j.autrev.2020.102554 PMC 바로가기 [Article Type] Article
The Ocular Surface and the Coronavirus Disease 2019: Does a Dual ‘Ocular Route’ Exist?Editorial Published on 2020-04-282022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] absence ACE-2 receptor ACE2 receptor analyzed association conjunctivitis Contamination Cornea coronavirus Coronavirus disease 2019 COVID-19 COVID-19 infection defined distribution droplet dual ocular route element expressed eye Face shield Health mechanism molecular ocular Ocular surface pandemic Prevent protective goggle replicate risk SARS-CoV-2 surface TMPRSS2 protein Transmission World Health Organization [DOI] 10.3390/jcm9051269 PMC 바로가기 [Article Type] Editorial
Global Spread of Coronavirus Disease 2019 and Malaria: An Epidemiological Paradox in the Early Stage of A PandemicEditorial Published on 2020-04-162022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] ACE-2 receptor ACE2 adverse effect Analysis analyzed Antimalarial drugs Antimalarials Antiviral coronavirus disease coronavirus epidemics Coronavirus infection COVID-19 COVID-19 outbreak distribution Endemic epidemiological epidemiological paradox Genetic variation initial malaria mechanism mechanism of action medications molecular pandemic paradox Population PROTECT protective role Research retinal toxicity Stage These data [DOI] 10.3390/jcm9041138 PMC 바로가기 [Article Type] Editorial