Approaching the Functional Annotation of Fungal Virulence Factors Using Cross-Species Genetic Interaction Profiling
종간 유전적 상호작용 프로파일링을 사용하여 진균 독성 인자의 기능적 주석 접근
Research Article
[키워드] accurate
AIDS
analyzed
annotation
approach
Author
C. neoforman
C. neoformans
C. neoformans gene
C. neoformans genes
calculation
Cancer
Cell
cell surface
Chemotherapy
compared
conserved
correlated
correlation
correlations
Cryptococcus neoforman
Cryptococcus neoformans
death
deletion mutant
deletion mutants
demonstrated
develop
disease
enhancement
expressed
expression
Factor
found
function
functional
functional annotation
fungal
fungal pathogens
fungi
Gene
gene deletion
gene function
Genetic
genetic interaction
genetic interactions
Golgi
Golgi apparatus
growth
HIV/AIDS
HIV/AIDS patients
human pathogen
identify
immunostimulatory
individuals
Infection
inhibiting
Interaction
interactions
lack
mannose
molecular
mutant
Organ transplant
organism
Organisms
ortholog
pathogen
pathogenicity
pathogenicity protein
Pathogens
patients
phagocytosis
predict
predicted
profile
profiles
Profiling
promote
quantification
Quantitative
recipient
required
S. cerevisiae
Saccharomyces cerevisiae
sequence
supported
suppression
susceptible
tested
the cell
understanding
utility
validation
virulence
virulence gene
yeast
[DOI] 10.1371/journal.pgen.1003168 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1003168 PMC 바로가기 [Article Type] Research Article