Deciphering the Pharmacological Mechanisms of Ma Xing Shi Gan Decoction against COVID-19 through Integrating Network Pharmacology and Experimental ExplorationPharmacology Published on 2020-11-262022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Adsorption analyzed Anti-inflammatory effects Antiviral caused Clinical symptoms component COVID-19 Critical Cytokine storm Decoction disease Efficacy exploration immune immunomodulatory Inflammation inflammatory lung injury Influenza inhibit inhibiting Intervention Lung injury Ma Xing Shi Gan decoction mechanism Medicine network network pharmacology outbreak pathway pharmacological mechanism Pharmacology Pneumonia Prevent public health Regulatory replication of SARS-CoV-2 Research Safe SARS-CoV-2 signaling pathway Tandem mass spectrometry targets TCM the epidemic therapeutic effect Toll-like receptor Traditional Chinese medicine Transcriptome treating COVID-19 Treatment Vaccine viral entry Viral pneumonia virus infection [DOI] 10.3389/fphar.2020.581691 PMC 바로가기 [Article Type] Pharmacology
Anti-Inflammatory Effects of Amantadine and Memantine: Possible Therapeutics for the Treatment of Covid-19?Communication Published on 2020-11-092022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] amantadine anti-inflammatory effect Anti-inflammatory effects COVID-19 COVID-19 disease Effect experimental model Hepatitis in vivo model Infection Inflammation Inflammatory response mechanism Memantine multiple sclerosis Neuroinflammation performed progression Research respiratory diseases SARS-CoV-2 Sepsis shown Spinal cord injury the SARS-CoV-2 Therapeutics therapy Treatment utility [DOI] 10.3390/jpm10040217 PMC 바로가기 [Article Type] Communication
Immune-Boosting, Antioxidant and Anti-inflammatory Food Supplements Targeting Pathogenesis of COVID-19Immunology Published on 2020-10-072022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] acute lung injury aerosol droplet Anti-inflammation Anti-inflammatory effects antioxidant Antiviral ARDS boost caused characterized Combination complex Compound Contact contagious Coronaviridae COVID-19 described disease dose drug Efficacy evaluated fibrosis food Food supplements Genome grouping help Host hyper inflammation immune system immune-boosting include innate immune response lactoferrin MERS-CoV nutraceutical oxidative stress Pathogenesis pathogenesis of COVID-19 Pneumonia positive-sense Prevent progression Prophylactic Protein quercetin Replication RNA SARS-CoV-1 SARS-CoV-2 Spread Support suppress survival targeting the disease therapeutic tissue transmitted Vaccine virus virus spread Vitamin C [DOI] 10.3389/fimmu.2020.570122 PMC 바로가기 [Article Type] Immunology
Stem Cell Based Therapy Option in COVID-19: Is It Really Promising?Review Article Published on 2020-10-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] Anti-inflammatory effects Cell cellular therapy China clinical clinical trial COVID-19 COVID-19 patient Efficacy Evidence feature ICTRP information investigated option other disease pharmacological agent Pneumonia public health registry respiratory problems Spread STEM stem cell the disease therapy Treatment trials virus WHO World Health Organization [DOI] 10.14336/AD.2020.0608 PMC 바로가기 [Article Type] Review Article
Potential mechanism prediction of Cold-Damp Plague Formula against COVID-19 via network pharmacology analysis and molecular dockingResearch Published on 2020-07-302022-11-01 Journal: Chinese Medicine [Category] COVID-19, [키워드] ACE2 activities analyses Analysis Anti-inflammatory Anti-inflammatory effects Anti-viral approach binding Blood cellular response circulation Cluster Cold‒Damp Plague Formula (CDPF) component components Compound COVID-19 database demonstrated disease docking drug-likeness effective Formula functional annotation Gene ontology global public health GO enrichment analysis host cells identify IL6 immune regulation ingredient Interaction KEGG KEGG pathway analysis Kyoto mechanism mechanism of action molecular molecular docking molecular mechanism network pharmacology oral bioavailability pathway pharmacological Potential potential molecular PPI PPI network predict provide provided receptor Regulation Result SARS-CoV-2 selected target targets Therapeutic benefit treat Treatment Version was used [DOI] 10.1186/s13020-020-00360-8 PMC 바로가기 [Article Type] Research
Corticosteroid administration for viral pneumonia: COVID-19 and beyondNarrative Review Published on 2020-06-272022-11-01 Journal: Clinical microbiology and infection : the official [Category] COVID-19, [키워드] acute respiratory distress acute respiratory syndrome administration Anti-inflammatory effects clinical symptom clinician Cochrane Library content coronavirus disease Corticosteroid corticosteroid therapy corticosteroid treatment COVID-19 criteria Critical disease dose Effect Effectiveness evaluate the effect Evidence Factor Fatality rate improvement increased mortality individual Inflammatory response Influenza Limited lymphopenia manuscript MERS MERS-CoV Middle East Mortality Nosocomial infection objective observational studies observational study Oxygenation pandemic Patient people with COVID-19 potential mechanism Randomized controlled trial receive reduce reported SARS SARS Coronavirus SARS-CoV SARS-CoV-2 searched severe COVID-19 severe disease severe viral pneumonia severity significantly higher Source Symptom syndrome therapy Viral pneumonia virus clearance Web of Science were used [DOI] 10.1016/j.cmi.2020.06.020 PMC 바로가기 [Article Type] Narrative Review
Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 CrisisReview Published on 2020-05-272022-10-31 Journal: Nutrients [Category] COVID-19, MERS, SARS, [키워드] ACE2 adequate diet Anti-inflammatory Anti-inflammatory effects antibody production antioxidant antioxidant effects carotenoid cell entry receptor challenge concerning coronavirus COVID-19 COVID-19 crisis crisis Cytokines diet dietary Dietary fiber enzyme example fatty acids Frequently General population global pandemic gut microbiota highlight immune response immune system include Infection infection risk Inflammation innate immune system macronutrients NF-kB nuclear factors nutrient oxidative stress Protein protein intake reactive oxygen species reduce shown Support System trace elements transcription factor transcription factors turn viral cellular infection vitamin A Vitamin C Vitamin D World Health Organization [DOI] 10.3390/nu12061562 PMC 바로가기 [Article Type] Review
Targeting the gut-lung microbiota axis by means of a high-fibre diet and probiotics may have anti-inflammatory effects in COVID-19 infectionArticle Published on 2020-01-012023-07-05 Journal: Therapeutic Advances in Respiratory Disease [Category] SARS, [키워드] Anti-inflammatory effects COVID-19 infection gut-lung microbiota aixs high-fibre diet Probiotics SARS-CoV-2 [DOI] 10.1177/1753466620937170 PMC 바로가기