Combined therapy of tocilizumab and corticosteroids in severe SARS-CoV-2 disease중증 SARS-CoV-2 질환에서 토실리주맙과 코르티코스테로이드의 병용 요법Case Reports Published on 2022-05-012022-09-12 Journal: Medicina intensiva [Category] COVID19(2023년), SARS, 진단, [키워드] Combined Corticosteroid disease severe SARS-CoV-2 therapy Tocilizumab [DOI] 10.1016/j.medine.2022.02.013 PMC 바로가기 [Article Type] Case Reports
Risk of herpes zoster in patients with rheumatoid arthritis in the biologics era from 2011 to 2015 and its association with methotrexate, biologics, and corticosteroids2011년부터 2015년까지 생물학적 제제 시대의 류마티스 관절염 환자에서 대상포진의 위험과 메토트렉세이트, 생물학적 제제 및 코르티코스테로이드와의 연관성Article Published on 2022-04-182023-05-31 Journal: Modern rheumatology [Category] 대상포진, 두창, 수두, 홍역, [키워드] Biologic disease-modifying antirheumatic drug Corticosteroid herpes zoster methotrexate rheumatoid arthritis [DOI] 10.1093/mr/roab026
Soluble IL-2R Levels at Baseline Predict the Development of Severe Respiratory Failure and Mortality in COVID-19 Patients기준선에서 가용성 IL-2R 수준은 COVID-19 환자에서 심각한 호흡 부전 및 사망의 발병을 예측합니다Article Published on 2022-04-102022-09-11 Journal: Viruses [Category] 바이오마커, [키워드] 95%CI Admission Algorithm Anakinra Biomarker change clinical outcomes coronavirus coronavirus disease Coronavirus disease-19 Corticosteroid Corticosteroids COVID-19 Critical cut-off Delta development died discharge disease severity Endpoint failure Follow-up hazard ratio Immunoglobulin Immunotherapy interquartile range Intravenous immunoglobulin Intubated intubation Laboratory Level Local local treatment marker median age moderate disease Mortality on admission Patient positive predict Predictive Predictive value receptor respiratory Respiratory failure risk Risk factors risk stratification severe disease severe respiratory failure significantly higher soluble interleukin-2 receptor SRF Stratification the strongest Tocilizumab Treatment were measured [DOI] 10.3390/v14040787 PMC 바로가기 [Article Type] Article
Auxora vs. placebo for the treatment of patients with severe COVID-19 pneumonia: a randomized-controlled clinical trialClinical Trial Published on 2022-04-082022-10-05 Journal: Critical Care [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory distress addition adverse event all-cause mortality all-cause mortality rate Auxora baseline calcium channel inhibitor chest imaging clinical trial Corticosteroid COVID-19 hospitalization CRAC CRAC channel inhibitor Day declining determine diagnosis of COVID-19 double-blind Efficacy endothelial integrity Enrollment enrolment groups Guidance Infection Invasive mechanical ventilation Laboratory testing less medication nasal Non-invasive occurred Oxygen therapy PaO Patient patients treated Placebo placebo-controlled trial Pneumonia polymerase chain primary endpoint Proinflammatory cytokine pulse oximetry Randomized randomized patients randomized-controlled receiving Regulatory required Respiratory failure SAE SAEs Safe secondary endpoint severe COVID-19 Severe COVID-19 pneumonia Standard of care Symptom syndrome time Time to recovery treat Treatment Trial with COVID-19 [DOI] 10.1186/s13054-022-03964-8 PMC 바로가기 [Article Type] Clinical Trial
Relationship of anti-SARS-CoV-2 IgG antibodies with Vitamin D and inflammatory markers in COVID-19 patients코로나19 환자에서 항 SARS-CoV-2 IgG 항체와 비타민 D 및 염증 표지자와의 관계Article Published on 2022-04-052022-09-12 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 바이오마커, 진단, [키워드] Affect age anti-SARS-CoV-2 anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibody Antibiotic therapy association Corticosteroid COVID-19 COVID-19 disease severity COVID-19 patient COVID-19 patients CRP determine diabete disease severity ESR form IgG IgGs IL-6 Inflammatory marker inflammatory state LDH magnitude negative correlation Older parameter Patient percentage positive correlation PROTECT relationship severe disease significantly significantly higher symptom onset Vitamin D vitamin D deficiency vitamin D level were measured [DOI] 10.1038/s41598-022-09785-7 PMC 바로가기 [Article Type] Article
Hepatitis B and C screening in hospitalized patients with SARS-CoV-2 infectionSARS-CoV-2 감염으로 입원한 환자의 B형 및 C형 간염 검사Article Published on 2022-04-012022-09-11 Journal: Gastroenterología y hepatología [Category] B형 간염, COVID19(2023년), SARS, 진단, 치료기술, [키워드] age Anti-HCV Antiviral treatment antiviral treatments candidate Comorbidities conducted Corticosteroid Corticosteroids COVID-19 Cribado Diagnosis diagnosis of COVID-19 died evaluate expected HBsAg HBV HBV infection HCV Hepatitis hepatitis B hepatitis C hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitals immunosuppressive Infection less limit male marker median age Older Patient patients with COVID-19 positive Prevalence Prevent previous diagnosis Prophylaxis Prospective Study Reactivation receive RNA SARS-CoV-2 SARS-COV-2 infection Screening screening program Spanish tested treated Treatment [DOI] 10.1016/j.gastrohep.2021.09.002 PMC 바로가기 [Article Type] Article
Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort studyObservational Study Published on 2022-04-012022-10-04 Journal: International Journal of Environmental Research an [Category] 임상, 치료법, [키워드] adjusted odds ratio administration Care chronic neurological disease clinical clinical decision Clinical practice cohort study Corticosteroid Corticosteroids COVID-19 Critical care Dementia demographics Dexamethasone discrepancy evaluate hospital Hydrocortisone identify Illness severity implementation independent Intervention ISARIC ISRCTN less likelihood Medical Research Council Methylprednisolone Older Patient patients with COVID-19 Prednisolone pregnant women Primary outcome Rate receive RECOVERY trial reduce mortality Registered significantly supplementary oxygen treated Treatment WHO [DOI] 10.1016/S2589-7500(22)00018-8 PMC 바로가기 [Article Type] Observational Study
Overview of clinical outcome and therapeutic effectiveness of Favipiravir in patients with COVID-19 admitted to intensive care unit, Riyadh, Saudi Arabia사우디아라비아 리야드의 중환자실에 입원한 COVID-19 환자에 대한 Favipiravir의 임상 결과 및 치료 효과 개요Article Published on 2022-04-012022-09-11 Journal: Journal of infection and public health [Category] COVID19(2023년), SARS, 임상, 진단, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome age analyzed antivirals approved ARDS BMI body mass body mass index Chloroquine Clinical outcome collected Comorbidities Comorbidity complications conducted control group Corticosteroid cough COVID-19 COVID-19 patient COVID-19 vaccine Critically ill critically ill COVID-19 patients Critically ill patient critically ill patients cytokine Cytokine storm diabetes Diabetes Mellitus effective Effectiveness Efficacy Efficacy and safety enrolled enzyme Favipiravir Fever FIVE FVP group had no heart disease hospital hypertension ICU ICUs IMPROVE inhibit intensive care intensive care unit intensive care units ischemic heart disease Kingdom majority male management medications not effective other treatment other treatments overall mortality P-value pandemic Patient patients with COVID-19 Potential treatment Randomized Research respiratory distress Respiratory distress syndrome retrospective cohort study RNA RNA polymerase Saudi Arabia severe acute respiratory distress syndrome severe symptoms Shortness of breath statistically significant Symptom syndrome the cytokine storm the disease the mean therapeutic therapeutic efficacy therapy Tocilizumab two groups Viral viral infection viral infections viral replication with COVID-19 [DOI] 10.1016/j.jiph.2022.01.013 PMC 바로가기 [Article Type] Article
Incidence of complications of herpes zoster in individuals on immunosuppressive therapy: A register-based population study면역억제 요법을 받는 개인에서 대상포진 합병증 발생률: 등록 기반 인구 연구Article Published on 2022-04-012023-05-31 Journal: The Journal of Infection [Category] 대상포진, 두창, 수두, 홍역, [키워드] Corticosteroid herpes zoster Immunosuppression Postherpetic neuralgia valacyclovir [DOI] 10.1016/j.jinf.2022.01.003
Prognostic factors and combined use of tocilizumab and corticosteroids in a Spanish cohort of elderly COVID-19 patients노인 COVID-19 환자의 스페인 코호트에서 예후 인자 및 토실리주맙과 코르티코스테로이드의 병용 사용Observational Study Published on 2022-04-012022-09-12 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] 95% confidence interval addition adjusted Admission age alcohol Analysis analyzed antiplatelet benefit Clinical course Cohort cohort of patient Combined combined use Coronavirus disease 2019 correlated Corticosteroid Corticosteroids COVID-19 COVID-19 disease COVID-19 patient CRP death disease Efficacy efficacy analysis elderly Elderly patient evaluated Factor hazard ratio high-risk patient higher risk hospital identify immunomodulatory therapy Immunosuppressive treatment IMPROVE indicated Infection LASSO Mask Mortality mortality rate multivariate Cox regression Older oxygen support parameter patients older performed Predictive Prognosis Prognostic factor protective factor Regression model shown Spanish standard treatment subsequent survival TCZ Tocilizumab Treatment variable [DOI] 10.1002/jmv.27488 PMC 바로가기 [Article Type] Observational Study