Defense

[키워드] Activation activator acute COVID-19 age allele alleles analyzed antiviral immunity Biomarker Blood BMI = body mass index body mass body mass index C-reactive protein cGMP contribute coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 = coronavirus disease 2019 Critical CRP = C-reactive protein D-dimer death Defense disease domain Effect gain-of-function Genetic genetic information genetic risk factor Genotype groups Haplotype Helicase high risk idea IFIH1 IFIH1 = interferon-induced with helicase c domain 1 IFN IFN = interferon IFN pathway Increased interferon interferon regulatory factor IRF = interferon regulatory factor IRF5 IRF7 IRF8 lupus erythematosus modulate Mortality nucleotide NYU = New York University older subjects OR = odds ratio pathway Patient positive Predictive Primary outcome PRKG1 PRKG1 = protein kinase cGMP-dependent 1 protective effect Protective effects Protein protein kinase Regulatory risk risk allele risk factor risk of death significantly Single nucleotide polymorphism SLE SLE = systemic lupus erythematosus SNP = single nucleotide polymorphism STAT4 STAT4 = signal transducer and activator of transcription 4. subjects Support systemic lupus erythematosus Transcription troponin Type Type I IFN type I interferon variants viral infections York younger patient younger patients
[DOI] 10.1016/j.trsl.2022.01.007 PMC 바로가기 [Article Type] Article