Evolution of SARS-CoV-2 in Spain during the First Two Years of the Pandemic: Circulating Variants, Amino Acid Conservation, and Genetic Variability in Structural, Non-Structural, and Accessory Proteins대유행의 첫 2년 동안 스페인에서 SARS-CoV-2의 진화: 구조적, 비구조적 및 부속 단백질의 순환 변이체, 아미노산 보존 및 유전적 다양성Article Published on 2022-06-072022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 변종, [키워드] Accessory accessory proteins acid Amino acid change circulating SARS-CoV-2 variant circulating SARS-CoV-2 variants circulation conservation conserved COVID-19 death diagnostic tests Epidemic epidemic wave epidemic waves Epidemiology Europe Evolution Frequency genetic diversity genetic variability GISAID database had more highest Lineage lineages monitoring Mutation mutation frequency non-structural proteins pandemic Protein SARS-CoV-2 SARS-CoV-2 mutation sequence Spain Spanish Spread structural protein structural proteins study period the SARS-CoV-2 Therapies Vaccines Variability Viral protein Year [DOI] 10.3390/ijms23126394 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Delta variant isolates from vaccinated individualsSARS-CoV-2 Delta 변이체는 예방접종을 받은 개인에서 분리됩니다.Article Published on 2022-06-042022-09-11 Journal: BMC Genomics [Category] COVID19(2023년), SARS, 변종, [키워드] addition Affect circulating Cluster collected conformational change COVID-19 cytosolic Delta Delta B.1.617.2 delta variant Disruption genetic diversity Genome sequencing Genomic analysis hydrophobic immune evasion induce isolate isolates Lineage Mutation mutations Non-synonymous mutation Nsp15 Nsps ORF1 ORF1b ORF7a ORF8 Oxford Nanopore MinION polar position positive sample predominant premature stop codon Protein SARS-CoV-2 SARS-CoV-2 delta SARS-CoV-2 virus SARS-CoV-2 viruses side chain Spike protein the spike protein transmembrane protein Transmissibility Transport vaccinated individual vaccinated individuals Vaccine variant variant of concern virus was performed Whole genome sequencing [DOI] 10.1186/s12864-022-08652-z PMC 바로가기 [Article Type] Article
Impact of natural selection on global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infectionSARS-CoV-2 감염과 관련된 유전자의 유전적 변이 및 임상 표현형과의 연관성에 대한 자연 선택의 영향Article Published on 2022-05-242022-09-11 Journal: Proceedings of the National Academy of Sciences of [Category] COVID19(2023년), SARS, 변종, [키워드] 1000 Genomes Project ACE2 ACE2 expression acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive African African diversity Amino acid amino acid change analyzed angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 Antigen association caused clinical phenotype clinical phenotypes complex coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 dipeptidyl peptidase Dipeptidyl peptidase 4 DPP4 Electronic health record Electronic health records enzyme European Genetic genetic diversity genetic variants Genetic variation Genome genomic Haplotype haplotypes Health host gene host genes Human identify Impact in some individual investigated involved Lineage locus LY6E lymphocyte minor allele frequency natural selection nonsynonymous variant pandemic patients with COVID-19 phenotype phenotype association. populations Positive selection protease Protein provide regulatory region SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2/COVID-19 Serine serine 2 severe acute respiratory syndrome Coronavirus target targets TMPRSS2 transmembrane transmembrane protease serine 2 variant Variation viral infections viruses [DOI] 10.1073/pnas.2123000119 PMC 바로가기 [Article Type] Article
Deep learning based on biologically interpretable genome representation predicts two types of human adaptation of SARS-CoV-2 variants생물학적으로 해석 가능한 게놈 표현에 기반한 딥 러닝은 SARS-CoV-2 변이체의 두 가지 유형의 인간 적응을 예측합니다Article Published on 2022-05-132022-09-11 Journal: Briefings in Bioinformatics [Category] COVID19(2023년), SARS, 변종, 치료법, [키워드] 3D convolutional neural networks A570D adaptation adaptive Alpha VOC Analysis applied Beta biological significance CNN Convolutional neural network coronavirus COVID-19 CoVs D1118H DCR deep Delta determinant dinucleotide dinucleotide composition representation distribution DNT dominant feature framework genetic diversity Genome glycoprotein human adaptation introduced linear Local Mutation omicron opposite pathogenicity performed predict predicted RdRP RdRps real time RNA virus RNA viruses RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants single-stranded Spike proteins ssRNA the spike protein Transmissibility Type variant variants variants of concern variants of interest viruses VOCs [DOI] 10.1093/bib/bbac036 PMC 바로가기 [Article Type] Article
Hemagglutinin Gene Variation Rate of H9N2 Avian Influenza Virus by Vaccine Intervention in ChinaArticle Published on 2022-05-132023-06-22 Journal: Viruses [Category] 조류인플루엔자, [키워드] Avian influenza virus genetic diversity H9N2 subtype vaccine intervention variation rate. [DOI] 10.3390/v14051043 PMC 바로가기
SARS-CoV-2 outbreak in Iran: The dynamics of the epidemic and evidence on two independent introductions이란의 SARS-CoV-2 발병: 전염병의 역동성과 두 가지 독립적인 도입에 대한 증거Article Published on 2022-05-012022-09-12 Journal: Transboundary and emerging diseases [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Analysis circulating Cluster community transmission country COVID-19 Critical D614G mutation defined early phase Epidemic Evidence Frequency genetic diversity geographical location Health increase in independent indicated Iran Lineage lineages occurred outbreak pandemic Phylogenetic phylogenetic study predict provided reduction in SARS-CoV-2 SARS-CoV-2 virus Sequencing Spread suggested the epidemic Transmission dynamics triggering Variation viral isolate viral lineage Viral transmission virus was performed while whole genome Whole genome sequencing whole-genome Whole-genome sequence [DOI] 10.1111/tbed.14104 PMC 바로가기 [Article Type] Article
Chirohepevirus from Bats: Insights into Hepatitis E Virus Diversity and EvolutionReview Published on 2022-04-272023-06-10 Journal: Viruses [Category] E형 간염, Fulltext, [키워드] bats Chirohepevirus genetic diversity genomic catheterization hepatitis E virus HEV-D molecular evolution [DOI] 10.3390/v14050905 PMC 바로가기 [Article Type] Review
Longitudinal Survey of Coronavirus Circulation and Diversity in Insectivorous Bat Colonies in ZimbabweArticle Published on 2022-04-092023-07-08 Journal: Viruses [Category] COVID19(2023년), [키워드] bat coronavirus (Bt CoVs) genetic diversity human–bat interaction reproductive phenology. Zimbabwe [DOI] 10.3390/v14040781 PMC 바로가기
Human seasonal influenza under COVID-19 and the potential consequences of influenza lineage eliminationArticle Published on 2022-03-312022-10-04 Journal: Nature Communications [Category] MERS, 신종인플루엔자, 치료기술, [키워드] Annual Asia Case report changes in China circulation consequence COVID-19 COVID-19 pandemic deaths distribution economic loss Epidemic Epidemics Epidemiology evolutionary dynamics genetic diversity Human Infection Influenza Influenza virus less Lineage measure molecular evolution morbidity offer outbreak Perspective Phylogenetic Policy and public health in microbiology population immunity public health measure seasonal Seasonal influenza sequence South suppressed Transmission Travel vaccine strain virus West WHO [DOI] 10.1038/s41467-022-29402-5 PMC 바로가기 [Article Type] Article
Molecular epidemiology of hepatitis B virus among HIV co-infected and mono-infected cohorts in Northwest EthiopiaArticle Published on 2022-03-242023-06-12 Journal: Virology Journal [Category] B형 간염, [키워드] Ethiopia genetic diversity HBV HIV/HBV co-infection. [DOI] 10.1186/s12985-022-01774-6 PMC 바로가기