Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent AxisArticle Published on 2020-07-172023-06-18 Journal: Cell Metabolism [Category] Fulltext, SARS, [키워드] COVID-19 diabetes Glycolysis HIF-1alpha Inflammation interferon metabolism Mitochondria monocyte SARS-CoV-2 [DOI] 10.1016/j.cmet.2020.07.007 PMC 바로가기
Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquineResearch Article Published on 2020-07-082022-10-30 Journal: Molecular Medicine [Category] Coronavirus, SARS, [키워드] Affect affected ATP autophagy cardiovascular disease caspase-1 caused Cell Chloroquine cleaved consolidation COVID-19 derivatives disease Doppler Effect enzyme exacerbated expected expression Extracellular fibrosis Glycolysis immunofluorescence increase Inflammasome Inflammatory inhibitor Ischemia Ischemic muscle isoform Laser Liver injury Lysosomal inhibition mice Microscopy modulated muscle myocytes oxidative phosphorylation oxygen patients with comorbidity Perfusion Protective Protein reduced reductions in Result Signaling significant increases in tibialis anterior treated viral disease was measured [DOI] 10.1186/s10020-020-00190-2 PMC 바로가기 [Article Type] Research Article
Effects of Dietary Carbohydrate to Lipid Ratios on Growth Performance, Muscle Fatty Acid Composition, and Intermediary Metabolism in Juvenile Black Seabream ( Acanthopagrus schlegelii )Original Research Published on 2020-06-032023-08-30 Journal: Frontiers in Physiology [Category] E형 간염, [키워드] black seabream CHO:L ratios gluconeogenesis Glycolysis Lipogenesis long-chain PUFA [DOI] 10.3389/fphys.2020.00507 PMC 바로가기 [Article Type] Original Research
The human milk protein-lipid complex HAMLET disrupts glycolysis and induces death in Streptococcus pneumoniae인간 모유 단백질-지질 복합체 HAMLET는 해당작용을 방해하고 폐렴구균에서 사멸을 유도한다.Article Published on 2019-12-202024-08-24 Journal: Brain stimulation [Category] 폐렴구균 감염증, [키워드] alpha-lactalbumin Antibiotics cell death energy metabolism enzyme inactivation Glycolysis HAMLET (human alpha-lactalbumin made lethal to tumor cells) human milk lactic acid membrane function metabolism oleic acid. Streptococcus Streptococcus pneumoniae
HIF1α-Dependent Metabolic Signals Control the Differentiation of Follicular Helper T CellsArticle Published on 2019-11-172023-06-08 Journal: Cells [Category] Fulltext, 신종인플루엔자, [키워드] B cell immunity Follicular helper T cell GC responses Glycolysis HIF1α infectious inflammation oxidative phosphorylation T cell differentiation virus infection [DOI] 10.3390/cells8111450 PMC 바로가기 [Article Type] Article
Analysis of long non-coding RNAs in neonatal piglets at different stages of porcine deltacoronavirus infectionResearch Article Published on 2019-04-112022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] Antiviral strategies Biomarkers cause characterized contagious coronavirus Degradation diarrhea differentially expressed expression data facilitate functional enrichment Glycolysis High throughput sequencing histidine identifying Infection infection process Infectious disease Interaction Interaction network intestinal intestinal wall investigated involved late stage lncRNA long non-coding RNA Long non-coding RNA (lncRNA) metabolism miRNAs mRNA Necrosis Neonatal pathway Porcine deltacoronavirus Porcine deltacoronavirus infection qRT-PCR validation reported Research Result Sequencing significant effect small intestine Stage supplementary material villus viral replication virulence vomiting [DOI] 10.1186/s12917-019-1862-4 PMC 바로가기 [Article Type] Research Article
Phosphoglycolate phosphatase is a metabolic proofreading enzyme essential for cellular function in Plasmodium bergheiArticle Published on 2019-03-292024-08-28 Journal: Brain stimulation [Category] 말라리아, [키워드] 2-phospho-L-lactate 2-phosphoglycolate 4-phosphoerythronate gene knockout Glycolysis malaria Metabolic regulation phosphatase phosphoglycolate phosphatase (PGP) Plasmodium berghei protozoan.
Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease항염증성 microRNA-146a는 식이 유발 대사 질환으로부터 생쥐를 보호합니다Research Article Published on 2019-02-152022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence adipose Adipose tissue Adiposity administration blockade blood glucose cellular cellular metabolism cellular respiration chronic inflammation Combination contribute Control controls creating Critical demonstrated develop Diabetic diabetic patient diabetic patients diet dysregulated Evidence expressed expression Factor fat genetics Glucose Glycolysis Human identifying Immune cell immune cells increase in Inflammation inflammatory function inflammatory gene inflammatory genes inflammatory pathways influence inhibitor Interaction investigated involved Macrophage macrophages mechanism metabolic disease metabolic pathway metabolic pathways metabolic processe metabolic processes metabolism mice microRNA miR-146 miRNA mTOR NF-κB NF-κB activation obese obesity pathway phenotype Phenotypes potential therapeutic target Prevent Pro-inflammatory genes PROTECT protective role provide Rapamycin reduced regulate regulated Regulatory represse Research RNA-sequencing shown Symptom tissue tissue macrophage Traf6 weight gain wild-type [DOI] 10.1371/journal.pgen.1007970 PMC 바로가기 [Article Type] Research Article
Infection and metabolism – Streptococcus pneumoniae metabolism facing the host environmentarticle Published on 2018-12-312024-09-01 Journal: Cytokine [Category] 폐렴구균 감염증, [키워드] energy metabolism Glycolysis Infection metabolism Streptococcus pneumoniae [Article Type] article
Inhibition of GLUTs by WZB117 mediates apoptosis in blood-stage Plasmodium parasites by breaking redox balanceArticle Published on 2018-09-052024-08-28 Journal: Biochemical and Biophysical Research Communications [Category] 말라리아, [키워드] Apoptosis GLUTs Glycolysis Plasmodium ROS WZB117.