Patterns of pharmaceuticals use during the first wave of COVID-19 pandemic in Athens, Greece as revealed by wastewater-based epidemiology제약의 패턴은 폐수 기반 역학에 의해 밝혀진 그리스 아테네에서 Covid-19 Pandemic의 첫 번째 물결 동안 사용됩니다.Article Published on 2021-12-012022-08-31 Journal: The Science of the total environment [Category] SARS, 치료제, [키워드] acute respiratory syndrome coronavirus analgesics Analysis Angiotensin II Antibiotics anticancer drugs antiviral drug antiviral drugs antivirals applied Asymptomatic blocker changes in chronic lung disease Comorbidity condition coronavirus coronavirus 2 correlated COVID-19 COVID-19 infection COVID-19 pandemic decrease demonstrated disease diuretics drug Drug consumption changes drugs effective Epidemiology First wave Greece healthy individuals heart disease hydrochlorothiazide Hydroxychloroquine hypertension in healthy individual Infection lack lockdown Lung disease MONITOR morbidity and mortality Non-invasive NSAID NSAIDS occur pandemic Paracetamol pattern public health receptor Receptor Blockers reduced respiratory SARS-CoV-2 screening methods severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe disease Treatment Vaccine valsartan various treatment various treatments was used wastewater Wastewater-based epidemiology Wide-scope screening methods. with COVID-19 [DOI] 10.1016/j.scitotenv.2021.149014 PMC 바로가기 [Article Type] Article
Kidney transplant recipients vaccinated before transplantation maintain superior humoral response to SARS-CoV-2 vaccine이식 전에 예방 접종을 받은 신장 이식 환자는 SARS-CoV-2 백신에 대해 우수한 체액 반응을 유지합니다.Article Published on 2021-12-012022-09-12 Journal: Clinical transplantation [Category] SARS, 진단, [키워드] analyzed anti-spike antibody anti-Spike IgG BNT162b2 Candidates Cohort Control COVID-19 develop dialysis healthcare healthy individuals humoral kidney transplant recipient kidney transplant recipients Kidney transplantation Lymphocyte count maintain negative Odds ratio Older age Patient Pfizer-BioNTech positive serology Protective recipient recommendation SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine Serologic response seropositive significantly lower Support sustained the patient vaccination Vaccine [DOI] 10.1111/ctr.14478 PMC 바로가기 [Article Type] Article
Is COVID-19 associated with latent toxoplasmosis?COVID-19는 잠재적인 톡소플라스마증과 관련이 있습니까?Article Published on 2021-12-012022-09-11 Journal: Environmental science and pollution research inter [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% confidence interval antibody association blood sample Blood samples control group control groups coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 negative COVID-19 patients demonstrated enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluate healthy individuals IgG individual Infection interquartile range IQR median median and interquartile range Patient patients with COVID-19 PCR-positive COVID-19 patients Prevalence prevalent separated Seroprevalence serum statistically significant T. gondii tested the patient Toxoplasma Toxoplasma gondii toxoplasmosis [DOI] 10.1007/s11356-021-17126-w PMC 바로가기 [Article Type] Article
Emerging SARS‐CoV‐2 variants can potentially break set epidemiological barriers in COVID‐19Review Published on 2021-11-292022-10-04 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, [키워드] absence accumulating ACE2 acute respiratory syndrome age antibodies antigenic sites binding causing changes in Comorbidities coronavirus coronavirus disease COVID‐19 COVID‐19 demographic disease severity driven by ENhance enzyme epidemiological Epidemiology Evidence expression female glycosylation greater Harbor Health healthy individual healthy individuals induce Infection interactions mechanisms Mutation mutations neutralization other proteases outcome pandemic prolonged viral shedding Proteases proteolytic cleavage RBD recent receptor receptor‐binding domain reduced repeated Replication resulting SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 variants sequence severe disease severe inflammation Sex show significant changes in Spike protein symptomatic the disease the RBD the spike protein tissue injury Transmissibility vaccination Vaccine vaccine breakthrough infection variant variants Viral load viral loads viral spike protein virus virus–host interaction Waves widespread women [DOI] 10.1002/jmv.27467 PMC 바로가기 [Article Type] Review
Comparative analysis of the diagnostic performance of five commercial COVID-19 qRT PCR kits used in India인도에서 사용되는 5 개의 상업용 CovID-19 QRT PCR 키트의 진단 성능의 비교 분석Article Published on 2021-11-102022-09-01 Journal: Scientific Reports [Category] MERS, 진단, 치료기술, [키워드] 2019-nCoV amplified assays clinical clinical samples clinically collected Comparative analysis Contact contact with control group control patients controls correlation Council COVID-19 criteria Ct values diagnosed diagnostic diagnostic testing disease Diseases evaluate evaluated feature FIVE followed by healthy healthy individual healthy individuals heterogeneity highest inclusion criteria India individual initial Medical research Microbiology Molecular biology other respiratory virus Other respiratory viruses pandemic Patient PCR Poor positive protocol provided Quality assurance respiratory Respiratory samples respiratory viral infections respiratory viruses RNA extraction routine diagnostic testing RT-PCR RT-PCR kit sample collection SARS-CoV-2 Sensitivity and specificity symptomatic TaqPath Viral Viral load viral loads Virology viruses were used [DOI] 10.1038/s41598-021-00852-z PMC 바로가기 [Article Type] Article
Elevated fecal and serum calprotectin in COVID-19 are not consistent with gastrointestinal symptomsArticle Published on 2021-11-092022-10-04 Journal: Scientific Reports [Category] 바이오마커, 치료기술, [키워드] acute phase association Biochemistry Biomarkers calprotectin caused cell damage controls COVID-19 COVID-19 case COVID-19 disease COVID-19 patient diarrhea disease severity elevated epithelial fecal Gastrointestinal symptom GI symptom Health care healthy control healthy individuals immune system immunology inflammation marker Inflammatory marker Inflammatory response investigated manifestation median Medical research not correlated not significantly different performed progressed progression SARS-COV-2 infection serum subgroup thought triggered uninfected were measured [DOI] 10.1038/s41598-021-01231-4 PMC 바로가기 [Article Type] Article
Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases Research Published on 2021-11-082022-10-05 Journal: Nature metabolism [Category] 바이오마커, [키워드] a metric aggregate Analysis approach can be used cardiometabolic disease Chronic kidney disease Coronary artery disease disease Effect events Follow-up Genetic predisposition healthy individuals independent information ischaemic stroke loci locus Myocardial infarction over Pathogenesis plasma Protein Proteins proteome Quantitative question representing risk risk allele shown Spread target therapeutic potential type 2 diabete type 2 diabetes underlying disease [DOI] 10.1038/s42255-021-00478-5 [Article Type] Research
Safety and immunogenicity of inactivated SARS-CoV-2 vaccines in healthy individuals: protocol for a systematic review and meta-analysis건강한 개인의 불활성 SARS-COV-2 백신의 안전성 및 면역 원성 : 체계적인 검토 및 메타 분석을위한 프로토콜Article Published on 2021-11-052022-08-31 Journal: BMJ Open [Category] MERS, meta-analysis, SARS, [키워드] abstracts Analysis approval assessment tool Bia clinical trial Cochrane Library collaboration conferences COVID-19 database Ethics evaluate evaluated event Grey literature healthy healthy individuals immunogenicity immunology in healthy individual inactivated inception infection control information Meta-analysis morbidity and mortality Patient peer-reviewed performed prevention of COVID-19 PROSPERO protocol provided randomised controlled trial Randomised controlled trials RCT RCTs registration number required Research review Safety SARS-CoV-2 vaccine Spread Stage statistical analysis systematic review tested Web of Science [DOI] 10.1136/bmjopen-2021-056106 PMC 바로가기 [Article Type] Article
Machine Learning-based Voice Assessment for the Detection of Positive and Recovered COVID-19 PatientsResearch article Published on 2021-11-012022-10-05 Journal: Journal of Voice [Category] 바이오마커, 진단, 치료기술, [키워드] Accuracy All study participant assessment Asymptomatic AUC binary classification carried clinically Comparisons conducted controls cough COVID COVID-19 COVID-19 patients COVID-19 symptom detectable detection determine diagnostic effective healthy individual healthy individuals healthy subjects identify individual Infection machine nasal swab outlined pandemic Patient patients Population positive positive COVID-19 provided recovered recovered COVID-19 patient recruited reported SARS-CoV-2 screening strategy screening test sensitivity Serological testing specificity Spread subject subjects subpopulation Surveillance sustained the disease Trial Variation virological test voice [DOI] 10.1016/j.jvoice.2021.11.004 [Article Type] Research article
Dysregulation of RNA interference components in COVID-19 patientsCOVID-19 환자에서 RNA 간섭 성분의 조절 조절Research Note Published on 2021-10-292022-09-10 Journal: BMC Research Notes [Category] 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Ago2 Antiviral China component coronavirus COVID-19 COVID-19 patient COVID-19 patients COVID-19patient COVID-19patients Defense defense mechanisms demonstrated DGCR8 Dicer Drosha dysregulated expression expression level Health healthy individuals healthy subjects inhibiting mechanism mRNA mRNAs Novel coronavirus objective Post-transcriptional gene silencing respiratory Respiratory illness Result RNA interference RNAi SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 severe respiratory illness statistically suggested supplementary material Viral Viral proteins virus virus replication Wuhan [DOI] 10.1186/s13104-021-05816-0 PMC 바로가기 [Article Type] Research Note