Immunocompromised patient – Page 7 – Communicable Diseases Research

Vaccination for SARS-CoV-2 in Hematological Patients

혈액학적 환자의 SARS-CoV-2 백신 접종

Review

Published on 2022-01-012022-09-11
Journal: Acta haematologica [Category] SARS, 임상, 진단,

Immune Response to BNT162b2 in Solid Organ Transplant Recipients: Negative Impact of Mycophenolate and High Responsiveness of SARS-CoV-2 Recovered Subjects against Delta Variant

Article

Published on 2021-12-182022-10-29
Journal: Microorganisms [Category] COVID-19,

[키워드] acute respiratory syndrome baseline BNT162b2 BNT162b2 vaccine cell-mediated response Cohort Complete Control Delta dose elicited evaluated ex-vivo ELISpot healthy subjects humoral Humoral response immune response Immunocompromised patient Impact impairment Italy median mRNA vaccine mycophenolate naïve negative observation of BNT162b2 patients positive quantification recipient recovered response responsiveness Result SARS-CoV-2 SARS-CoV-2 neutralizing antibody Seroconversion significantly lower Solid solid organ transplant Solid organ transplant recipients subject subset Support T-cell Response the SARS-CoV-2 Transplant uninfected vaccination vaccination schedule Vaccine variant virus was performed
[DOI] 10.3390/microorganisms9122622 PMC 바로가기 [Article Type] Article

Analysis of antibody responses after COVID-19 vaccination in liver transplant recipients and those with chronic liver diseases

간 이식 환자 및 만성 간 질환 환자의 코로나19 백신 접종 후 항체 반응 분석

Article

Published on 2021-12-012022-09-12
Journal: Journal of hepatology [Category] MERS, SARS, 진단,

[키워드] adjusted antibody Antibody Response chronic liver disease cirrhosis CLD Clinical efficacy COVID-19 vaccination COVID-19 vaccine defined dose Efficacy enrolled evaluate Factors immune response Immunocompromised Immunocompromised patient Immunosuppression Immunosuppressive medication Johnson & Johnson liver liver transplant median titer medication Moderna mRNA vaccine multivariable analysis Patient patient population patients performed Pfizer Poor Prospective Study recipient recipients responses SARS-CoV-2 SARS-CoV-2 vaccination Serious Adverse Events single dose Spike protein Trial U/mL undetectable vaccination Vaccine
[DOI] 10.1016/j.jhep.2021.08.008 PMC 바로가기 [Article Type] Article

Serologic response to COVID-19 infection and/or vaccine in cancer patients on active treatment

활성 치료 중인 암 환자의 COVID-19 감염 및/또는 백신에 대한 혈청학적 반응

Article

Published on 2021-12-012022-09-11
Journal: ESMO open [Category] SARS, 변종, 치료법,

[키워드] active treatment anti-S Anti-S1 antibody antibody response rate Antibody titer biologic BNT162b2 BNT162b2 mRNA BNT162b2 mRNA COVID-19 vaccine booster Cancer cancer patient Cancer patients Chemotherapy Chemotherapy treatment Cohort control group COVID-19 COVID-19 infection COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines domain dose evaluated Health care Health care worker humoral identify Immunocompromised Immunocompromised patient Immunocompromised patients immunogenic immunogenicity Immunologic immunologic response Immunotherapy Infection less metastatic disease multiple regression model natural infection Neutralizing antibody titer Odds ratio other treatment other treatments Patient positive positive response reduced response rate S1/S2 SARS-CoV-2 variant SARS-CoV-2 variants serologic Serologic response serologic test serologic tests serological surveillance shown significantly solid tumor solid tumors Specific subgroup subgroups the SARS-CoV-2 Treatment tumors vaccination Vaccine vaccine doses Virological were measured
[DOI] 10.1016/j.esmoop.2021.100283 PMC 바로가기 [Article Type] Article

Methotrexate as a safe immunosuppressive agent during the COVID-19 pandemic

Observational Study

Published on 2021-12-012022-10-05
Journal: International immunopharmacology [Category] SARS, 임상,

The therapeutic dilemma of immunosuppressive drugs for refractory cardiac sarcoidosis in COVID-19 infection

COVID-19 감염에서 내화성 심장 유육종증에 대한 면역 억제제의 치료 딜레마.

Case Reports

Published on 2021-12-012022-08-31
Journal: ESC heart failure [Category] MERS, SARS, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration arrhythmia Arrhythmias coronavirus coronavirus disease Coronavirus disease 2019 Corticosteroid Corticosteroids COVID-19 COVID-19 infection Dexamethasone discharge effective High dose hospital Immunocompromised patient immunology immunosuppressive agent Immunosuppressive agents immunosuppressive drug interruption intravenous Intravenous administration life-threatening maintenance dose methotrexate outbreak pandemic Patient patients with COVID-19 Prednisolone receiving refractory Refractory cardiac sarcoidosis regimen respiratory resulting sarcoidosis SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) therapeutic therapy treated Treatment ventricular woman
[DOI] 10.1002/ehf2.13676 PMC 바로가기 [Article Type] Case Reports

Safety and efficacy of the mRNA BNT162b2 vaccine against SARS-CoV-2 in five groups of immunocompromised patients and healthy controls in a prospective open-label clinical trial

5 개의 면역 저하 환자 및 전향 적 개방형 임상 시험에서 건강한 대조군에서 SARS-COV-2에 대한 mRNA BNT162B2 백신의 안전성 및 효능

Research paper

Published on 2021-11-302022-08-13
Journal: EBioMedicine [Category] MERS, SARS, 임상,

[키워드] Adverse adverse events Adverse reaction Allogeneic allogeneic hematopoietic stem cell transplantation Antibody titre antibody titres BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccination CAR T, Chimeric antigen receptor T CAR-T Cell Cell therapy certain immunocompromised patient groups chronic lymphocytic leukemia clinical trial clinical trials CLL CLL, Chronic lymphocytic leukemia Control controls Council COVID-19, Coronavirus disease 2019 disorder Efficacy event excluded finding FIVE five group foundation funding generally mild group healthy control healthy controls Hematopoietic stem cell highlight HIV HIV, Human immunodeficiency virus HSCT, Allogeneic hematopoietic stem cell transplantation Human immunodeficiency virus human stem-cell transplantation Ibrutinib Immunity Immunocompromised Immunocompromised patient immunocompromised patient group Immunocompromised patients immunodeficiency disorder immunodeficiency disorders IMPROVE Infection ITT, Intention to treat Knut leukemia Lymphocytic leukemia mPP, Modified per protocol mRNA BNT162b2 vaccine mRNA vaccination mycophenolate mycophenolate mofetil occurred of BNT162b2 Open-label organ transplantation organization organizations Patient patient group patient groups PID, Primary immunodeficiency disorders PP, Per protocol primary endpoint Primary Immunodeficiency Prospective clinical trial Rate Region Safe Safety SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 second dose secondary endpoint Secondary endpoints selected serious adverse reaction Seroconversion seroconversion rate seroconverted solid organ solid organ transplantation SOT SOT, Solid organ transplantation stem cell subgroups subject Swedish T cell therapy Treatment vaccination against COVID-19 vaccine dose virus infection
[DOI] 10.1016/j.ebiom.2021.103705 PMC 바로가기 [Article Type] Research paper

Emerging Trends in the Epidemiology of COVID-19: The Croatian ‘One Health’ Perspective

Covid-19의 역학에서 새로운 트렌드 : 크로아티아 '하나의 건강'관점

Review

Published on 2021-11-242022-09-01
Journal: Viruses [Category] MERS, SARS, 변종, 진단, 치료기술,

Association Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity

mRNA 백신 접종과 COVID-19 입원 및 질병 중증도 사이의 연관성

Article

Published on 2021-11-232022-09-11
Journal: JAMA [Category] SARS, 변종,

[키워드] 95% CI absence accounted adjusted adults hospitalized Alpha Analysis association benefit black BNT162b2 Case-control Control control patient controls COVID-19 COVID-19 hospitalization COVID-19 patient COVID-19 patients COVID-19 vaccination COVID-19 vaccine Critical disease Date death delta variant Delta variants develop disease Disease progression disease severity enrolled evaluate evaluated Final Follow-up Hispanic Hospitalization hospitalizations Hospitalized Immunocompromised Immunocompromised patient Immunocompromised patients immunocompromising condition individuals Invasive mechanical ventilation less likelihood mechanical ventilation median age Moderna mRNA mRNA COVID-19 vaccines mRNA-1273 multivariable logistic regression outcome Patient patients hospitalized patients with COVID-19 progression risk reduction SARS-CoV-2 sequenced significantly vaccination vaccine breakthrough infection vaccine breakthrough infections were measured with COVID-19
[DOI] 10.1001/jama.2021.19499 PMC 바로가기 [Article Type] Article

The Emergence of Cryptococcemia in COVID-19 Infection: A Case Report

Internal Medicine

Published on 2021-11-202022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] acute respiratory distress association Blood C. neoformans Case report Central nervous system clearance clinical suspicion clinically coronavirus coronavirus disease COVID-19 COVID-19 patient Cryptococcemia Cryptococcus neoforman cryptococcus neoformans (c. neoformans) Culture demonstrated detrimental Dexamethasone Diabetes Mellitus diagnosed emergence fungal fungemia Hispanic Host hypertension immunocompetent Immunocompromised patient Infection infections intravenous maintaining meningeal irritation Mortality Neurological deficit obesity opportunistic infection pandemic past medical history Patient Prevent Repeat report syndrome Topic treated treating COVID-19 patient
[DOI] 10.7759/cureus.19761 PMC 바로가기 [Article Type] Internal Medicine