Anti-SARS-CoV-2 IgA and IgG in human milk after vaccination is dependent on vaccine type and previous SARS-CoV-2 exposure: a longitudinal study백신 접종 후 모유 내 Anti-SARS-CoV-2 IgA 및 IgG는 백신 유형 및 이전 SARS-CoV-2 노출에 따라 다릅니다. 종단 연구Observational Study Published on 2022-04-212022-09-12 Journal: Genome Medicine [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] age anti-SARS-CoV-2 anti-SARS-CoV-2 IgG antibodies antibody AstraZeneca baseline BNT162b2 Breast breast milk ChAdOx1 nCoV-19 collected Course COVID-19 COVID-19 vaccination COVID-19 vaccine dependent on distribution dose evaluate first dose group healthcare human milk IgA IgA antibodies IgA level IgG IgG antibody immunoglobulins Infant lactating lactating women Level Moderna mother mRNA vaccine mRNA-1273 mRNA-based vaccine persistence prospective observational study Protective Protective antibody reactivity receiving SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection second dose Seven significantly higher Spain the vaccine transfer vaccination Vaccine Vaccines virus women [DOI] 10.1186/s13073-022-01043-9 PMC 바로가기 [Article Type] Observational Study
SARS-CoV-2 Spike Protein Binding of Glycated Serum Albumin-Its Potential Role in the Pathogenesis of the COVID-19 Clinical Syndromes and Bias towards Individuals with Pre-Diabetes/Type 2 Diabetes and Metabolic Diseases당화 혈청 알부민의 SARS-CoV-2 스파이크 단백질 결합-COVID-19 임상 증후군의 발병에 대한 잠재적 역할 및 당뇨병 전단계/2형 당뇨병 및 대사 질환이 있는 개인에 대한 편견Article Published on 2022-04-082022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 진단, 치료법, [키워드] acute respiratory distress albumin analysed Anti-nucleocapsid antibodies Anti-spike anti-spike and anti-nucleocapsid antibodies antibody atherosclerotic Bacteria Bia binding capture clinical Complete convalescent convalescent plasma COVID-19 Diabetic disease end product explain flight form fusion glycated albumin high affinity Human serum albumin immune evasion immune response immunoglobulins individual mass spectrometry metabolic metabolic disease molecular feature molecular features nucleocapsid nucleocapsid protein Nucleocapsid proteins pathogenic pathology Patient plasma protein plasma proteins Potential pre-fusion preference respiratory distress role SARS-CoV-2 SARS-COV-2 infection semi-automated magnetic rack serum albumin Serum protein serum proteins severity spike Spike protein the spike protein virus viruses [DOI] 10.3390/ijms23084126 PMC 바로가기 [Article Type] Article
A Novel Quantitative Multi-Component Serological Assay for SARS-CoV-2 Vaccine EvaluationSARS-CoV-2 백신 평가를 위한 새로운 정량적 다성분 혈청학적 분석Article Published on 2022-03-152022-09-11 Journal: Analytical Chemistry [Category] MERS, SARS, 진단, 치료법, [키워드] Accuracy Algorithm Analysis anti-SARS-CoV-2 array assays carried clinical trials conditions COVID-19 exposure times fluorescent generate house humoral Humoral response IgA IgG IgM Immunoglobulin immunoglobulins International international standard linear linearity methodology Microarray naïve normalized novel Nucleocapsid proteins positive Precision q-RT-PCR qRT-PCR quantitation Quantitative Receptor binding domain Result SARS-CoV-2 SARS-CoV-2 patients SARS-CoV-2 spike SARS-CoV-2 vaccines sera seroconverted serum Specific specificity the microarray the SARS-CoV-2 the WHO unique Vaccine [DOI] 10.1021/acs.analchem.1c05264 PMC 바로가기 [Article Type] Article
Development of Improved High-Performance Liquid Chromatography Method for the Determination of Residual Caprylic Acid in Formulations of Human ImmunoglobulinsArticle Published on 2022-03-032022-10-30 Journal: Molecules [Category] Coronavirus, MERS, SARS, [키워드] 1:1 acid Analysis anti-SARS-CoV-2 applied caprylic acid Chromatography component convalescent convalescent anti-SARS-CoV-2 human plasma demonstrated Determination development factorial design Formulation fraction high-performance liquid chromatography method Human human immunoglobulin human immunoglobulins Human plasma ICH immunoglobulins Improved Laboratory linear liquid parameter preserved produced Quality Quality control quantification residual stationary supernatant therapeutic use validation was performed [DOI] 10.3390/molecules27051665 PMC 바로가기 [Article Type] Article
Peripheral Neuropathy Evaluations of Patients With Prolonged Long COVID장기간 코로나 환자의 말초 신경병증 평가Article Published on 2022-03-012022-09-12 Journal: Neurology® neuroimmunology & neuroinflammation [Category] MERS, 진단, [키워드] acute respiratory syndrome affecting age analyzed appear autonomic average averaged Complete coronavirus COVID COVID-19 Critical cross-sectional diagnosed diagnoses evaluated Evidence female immune dysregulation immunoglobulins Immunotherapy Infection Interpretation Latino Long longitudinal Longitudinal data mechanism Mild Neuropathy one patient outcomes participant Patient peripheral Prolonged reported risk SARS-CoV-2 skin biopsies suggested Symptom Symptoms Treatment World Health Organization [DOI] 10.1212/NXI.0000000000001146 PMC 바로가기 [Article Type] Article
SARS-CoV-2 enzyme-linked immunosorbent assays as proxies for plaque reduction neutralisation testsSARS-COV-2 효소-연결 면역 흡착제 분석 플라크 환원 중화 시험을위한 프록시로서Clinical Trial Published on 2022-03-012022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 임상, 진단, 치료기술, 치료법, 치료제, [키워드] antibodies can be used cells coronavirus correlated detect determined by Diagnostic markers diagnostic test diagnostic tests ELISA enzyme enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays evaluated generate IgG IgG and IgM IgM immune response immune responses Immunoglobulin immunoglobulins infecting likelihood magnitude MOST NAb NAbs neutralisation test neutralising Neutralising Antibodies neutralising antibody nucleocapsid protein plaque Prevent PRNT Receptor binding domain reduction respiratory Respiratory Coronavirus rising robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 spike severe acute respiratory coronavirus severe acute respiratory coronavirus 2 Spread subunit titre viral infection virus [DOI] 10.1038/s41598-022-07263-8 PMC 바로가기 [Article Type] Clinical Trial
A systematic review and meta-analysis of the accuracy of SARS-COV-2 IGM and IGG tests in individuals with COVID-19COVID-19 환자를 대상으로 한 SARS-COV-2 IGM 및 IGG 검사의 정확도에 대한 체계적인 검토 및 메타 분석Review Published on 2022-03-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Accuracy antibody AUC Chain Reaction Cochrane Library complementary confirmation contribute database databases diagnostic Diagnostic meta-analysis diagnostic testing eligible evaluate exposure to high accuracy Humoral response humoral responses IgG antibodies IgM and IgG Immunoglobulin immunoglobulins immunosurveillance index individuals with COVID-19 Infection literature Meta-analysis nucleic acid Nursing observational studies observational study polymerase chain polymerase chain reaction Research reverse transcriptase Reverse transcriptase polymerase chain reaction RT-PCR SARS-CoV-2 SARS-COV-2 infection sensitivity Sensitivity and specificity serology specificity systematic review the disease transcriptase utility Viral viral nucleic acid virus was performed Web of Science [DOI] 10.1016/j.jcv.2022.105121 PMC 바로가기 [Article Type] Review
Persistence of humoral response upon SARS-CoV-2 infectionSARS-CoV-2 감염 시 체액 반응 지속Article Published on 2022-03-012022-09-11 Journal: Reviews in Medical Virology [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] adaptive Adults antibody Antibody Response comparability COVID-19 detectability Economy eight global health Health humoral Humoral response IgA IgG IgM immune responses Immunity Immunoglobulin Immunoglobulin G immunoglobulins in some majority memory B mucosal Neutralizing antibodies neutralizing antibody neutralizing capacity pandemic PCR-confirmed persistence progression Re-infection reported SARS-CoV-2 SARS-COV-2 infection sensitive assay sensitive assays seropositive individual seropositive individuals T cell T cells tested virus variants while [DOI] 10.1002/rmv.2272 PMC 바로가기 [Article Type] Article
SARS-CoV-2 RNA and antibody detection in breast milk from a prospective multicentre study in Spain스페인의 전향적 다기관 연구에서 얻은 모유 내 SARS-CoV-2 RNA 및 항체 검출Multicenter Study Published on 2022-03-012022-09-11 Journal: Archives of disease in childhood. Fetal and neonat [Category] MERS, SARS, 진단, 치료기술, 치료법, 치료제, [키워드] antibody Antibody detection antibody isotypes Antibody Response Breast feeding breast milk Breastfeeding Concentration control group COVID-19 determine develop domain Evidence global health Health health centres highlight IgA IgG IgM and IgG Immunoglobulin immunoglobulins isotype longitudinal study Microbiology milk mother multicentre neonatology Nucleocapsid gene outcome pandemic patients with COVID-19 persistence positive Presence protocol provide raised Receptor-binding domain recommendation registration number SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 spike protein scientific evidence Spain Spike protein Support the antibody response the receptor-binding domain the SARS-CoV-2 transfer Trial Registration Number Variability women [DOI] 10.1136/archdischild-2021-322463 PMC 바로가기 [Article Type] Multicenter Study
Impact of SARS-CoV-2 on saliva: TNF-⍺, IL-6, IL-10, lactoferrin, lysozyme, IgG, IgA, and IgMSARS-CoV-2가 타액에 미치는 영향: TNF-⍺, IL-6, IL-10, 락토페린, 리소자임, IgG, IgA 및 IgMArticle Published on 2022-03-012022-09-11 Journal: Journal of oral biosciences [Category] MERS, SARS, 진단, 치료기술, [키워드] acute SARS-CoV-2 infection airway Alter Analysis antimicrobial antimicrobial peptides Asymptomatic carried Chain Reaction components Concentration Control control group COVID-19 COVID-19 symptom COVID-19 symptoms Defense detect diagnosis of SARS-CoV-2 ELISA evaluate female group IgA IgG IgM IL-10 IL-6 immune immunoglobulins Impact increase in Infection Interleukins lactoferrin less longitudinal study lysozyme male Patient patients with COVID-19 PCR peptides polymerase chain polymerase chain reaction Prognosis Real-time PCR recovered patient Saliva salivary SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic significantly symptoms of COVID-19 understanding Volunteer [DOI] 10.1016/j.job.2022.01.007 PMC 바로가기 [Article Type] Article