Laboratory tests – Page 7 – Communicable Diseases Research

SARS-CoV-2 PCR positivity rate and seroprevalence of related antibodies among a sample of patients in Cairo: Pre-wave 2 results of a screening program in a university hospital

카이로 환자 검체 중 SARS-CoV-2 PCR 양성률 및 관련 항체 혈청 유병률: 대학 병원에서 실시한 검진 프로그램의 Pre-wave 2 결과

Research Article

Published on 2021-07-152022-09-12
Journal: PLoS ONE [Category] MERS, 진단,

Single-cell analysis reveals cell communication triggered by macrophages associated with the reduction and exhaustion of CD8 + T cells in COVID-19

단일 세포 분석은 COVID-19에서 CD8 + T 세포의 감소 및 고갈과 관련된 대식세포에 의해 촉발된 세포 통신을 보여줍니다

Observational Study

Published on 2021-07-082022-09-12
Journal: Cell Communication and Signaling : CCS [Category] 임상, 진단,

[키워드] activity acute respiratory syndrome Algorithm Analysis analyzed AST AUROC Bronchoalveolar lavage fluid calculate caused CD4 CD8 Cell cell types cellular clinical collected composed condition contributed coronavirus coronavirus disease COVID-19 COVID-19 pathogenesis COVID-19 patients CXCL10 cytokine D-dimer demonstrated described driving Efficacy enrolled Flow cytometry analysis functional heterogeneity hospitalized patient hypoxia IGF1 IL10 IL1β IL6 Immune cell IMPROVE independent risk factor Infection Inflammatory information Interaction interactions Laboratory tests Logistic regression analysis Macrophage Measures microenvironment moderate disease molecular mechanism multivariate offer outbreak outcome pandemic parameters pathway Patient Predictive ranged reduction respiratory immune Result retrospective reveal risk SARS-CoV-2 scRNA-seq data selective serum cytokine severe disease severity of COVID-19 significantly lower Single cell RNA-sequencing single-cell single-cell analysis subtype supplementary material T cell T cell subset T cells target therapy TNFα Trial registration triggered understanding Vaccines was used WBC Weighting were measured
[DOI] 10.1186/s12964-021-00754-7 PMC 바로가기 [Article Type] Observational Study

Early use of nitazoxanide in mild COVID-19 disease: randomised, placebo-controlled trial

Randomized Controlled Trial

Published on 2021-07-082022-10-05
Journal: The European Respiratory Journal [Category] Fulltext, SARS, 임상,

[키워드] 1:1 acute respiratory syndrome Adverse analysed antiviral activity ARMS collected Complete coronavirus coronavirus disease COVID-19 double-blind dry cough enrolled event Evidence fatigue Fever first dose hospitalisation in vitro Infection Inflammation interquartile range Laboratory tests Mild multicentre Nasopharyngeal swab nitazoxanide not differ not significantly different Other outcome Patient Placebo placebo group placebo-controlled trial presenting Primary outcome randomised receive reduced resolution of symptoms reverse transcriptase PCR Safe SARS-CoV-2 SARS-COV-2 infection screened secondary secondary outcome Serious Adverse Event serum biomarker significantly study drug study visit Symptom symptom onset symptom resolution therapy Viral load viral load reduction was reduced
[DOI] 10.1183/13993003.03725-2020 PMC 바로가기 [Article Type] Randomized Controlled Trial

Evaluation of the efficacy and safety of recombinant erythropoietin on the improvement of hospitalised COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial

입원한 COVID-19 환자의 개선에 대한 재조합 에리트로포이에틴의 효능 및 안전성 평가: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-07-062022-09-10
Journal: Trials [Category] SARS, 임상,

[키워드] 1:1 48 hours Adverse reaction Adverse reactions age approved Arm Bandar Abbas Blinding block randomization blood pressure Care checked chronic lung disease clinical clinical symptom clinical trial clinical trials Committee company comparator Patients composite endpoint control group Controlled clinical trial controls Coronary heart disease COVID-19 COVID-19 patient COVID-19 patients CRP Deep vein Deep vein thrombosis diabetes Diabetes Mellitus Diastolic blood pressure dissemination distilled water Efficacy and safety element End-stage renal disease endogenous enoxaparin erythropoietin ethics committee evaluate evaluate the effect excluded exclusion criteria expected Haemoglobin Health Health care heart disease hospitalised hospitalised COVID-19 patients Hypoxemia immune system infiltration injection intervals Intervention intervention group investigator Iran Laboratory test Laboratory tests LDH Liver disease Local Lung disease lung field lung infiltration lymphocyte Lymphocyte count lymphopenia Medical Science Medical Sciences medication minute number objective oral contraceptive outcome oxygen oxygen partial pressure oxygen saturation parallel-group partial pressure participant Patient PCR performed pharmaceutical Pharmaceutical Company Phase 2 Placebo positive Prevent principal investigator protocol randomised randomised controlled trial Randomized Randomly receive recombinant erythropoietin recruitment Registered registry renal disease reported respiratory respiratory rate Sample size saturation severe COVID-19 symptom severe COVID-19 symptoms Side effect Side effects Standard Standard of care status sterile water Study protocol subcutaneous injection subject supplementary material Systolic blood pressure tachypnea technology the ethics committee thrombosis title Treatment protocol treatment protocols Trial registration university vital signs water water for injection weakened immune system website
[DOI] 10.1186/s13063-021-05363-w PMC 바로가기 [Article Type] Letter

COVID-19-related laboratory coagulation findings

Review

Published on 2021-07-012023-07-02
Journal: International journal of laboratory hematology [Category] SARS,

[키워드] anticoagulation coagulation assays Coagulopathy coronavirus COVID-19 Hemostasis Laboratory tests Thromboembolism
[DOI] 10.1111/ijlh.13547 PMC 바로가기 [Article Type] Review

Early predictors of mortality for moderate to severely ill patients with Covid-19

Observational Study

Published on 2021-07-012022-10-05
Journal: The American journal of emergency medicine [Category] SARS, 임상,

[키워드] 2019 novel coronavirus disease 30-day mortality rate affecting age Algorithms analyzed C-reactive protein characteristic clinical condition COVID-19 COVID-19 pandemic CRP CRP level CRP levels decrease determine Determining disease Dyspnea elevated Factor Laboratory Laboratory tests male moderate Mortality neutrophil counts Novel coronavirus parameter Patient patient treatment patients patients older polymerase chain predict predicted predictor Primary outcome pulse regression analysis SARS-COV-2 infection severely ill patient significantly the patient was determined were excluded White blood cell
[DOI] 10.1016/j.ajem.2020.08.076 PMC 바로가기 [Article Type] Observational Study

US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 2021

2021년 3월 2일부터 4월 21일까지 Ad26.COV2.S 백신 접종 후 혈소판 감소증을 동반한 대뇌 정맥동 혈전증에 대한 미국 사례 보고

Case Reports

Published on 2021-06-222022-09-11
Journal: JAMA [Category] 비임상,

[키워드] Ad26 Ad26.COV2.S Ad26.COV2.S vaccine adenoviral vector Adverse age antibody AstraZeneca authorization Autoimmune back pain breath Case series case sery cerebral ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine clinical Clinical course Clinicians Contraceptive use Course COVID-19 vaccine death described Diagnosis discharged home dose ELISA Emergency Emergency use authorization enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay EUA Europe events Follow-up Guidance headache heparin heparin treatment heparin-induced thrombocytopenia Hospitalization Hospitalized Hypothyroidism ICU care initial intensive care intensive care unit Intracerebral hemorrhage Laboratory tests mechanism medical record National non-ICU obesity oral contraceptive outcome Patient positive ranged receipt recipients report reported Reporting resulting risk factor Sinus Sinus thrombosis symptom onset System tested thrombocytopenia thrombosis time Treatment vaccination venous venous sinus white women
[DOI] 10.1001/jama.2021.7517 PMC 바로가기 [Article Type] Case Reports

SARS-CoV-2 Infection in Health Workers: Analysis from Verona SIEROEPID Study during the Pre-Vaccination Era

의료 종사자의 SARS-CoV-2 감염: 백신 접종 전 시대의 베로나 SIEROEPID 연구 분석

Article

Published on 2021-06-142022-09-10
Journal: International Journal of Environmental Research an [Category] MERS, SARS, 진단, 치료기술,

[키워드] 95% CI analyzed Antibody detection Antibody titre baseline Biobank Cohen’s kappa contribute COVID-19 dataset Demographic variables enrolled epidemiological Health health worker health workers hospital IgA IgG IgG and IgM IgM Immunological response increase in Italy Laboratory test Laboratory tests large sample longitudinal design management National number of infected risk Risk assessment SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection sensitivity serological test Serological tests Serosurvey Serum level specificity Spread spring statistically statistically significant Support Surveillance Swab Swab test swabs unit university university hospital vaccination Verona virus working
[DOI] 10.3390/ijerph18126446 PMC 바로가기 [Article Type] Article

Bilateral Chilblain-like Lesions of the Toes Characterized by Microvascular Remodeling in Adolescents During the COVID-19 Pandemic

COVID-19 팬데믹 기간 동안 청소년의 미세혈관 리모델링으로 특징지어지는 발가락의 양측 Chilblain 유사 병변

Research

Published on 2021-06-102022-09-12
Journal: JAMA Network Open [Category] MERS, SARS, 진단,

[키워드] Adolescent age Analysis association Autoimmune Bilateral blood vessel case sery changes in characterized chilblain contributed Course COVID-19 COVID-19 pandemic cutaneous manifestation Cutaneous manifestations cyanotic described distal enrolled erythematous excluded finding First wave healthy help highlight histologic hospital Importance In situ hybridization Inflammatory investigated Italy laboratory feature Laboratory test Laboratory tests lesion lesions lobular male measure mechanisms median Mild molecular Nasopharyngeal swab objective occurred participant performed perivascular Point Relevance remodeling Result SARS-CoV-2 SARS-COV-2 infection serologic testing setting specimen Support Swab systemic inflammation Thrombophilia Toe triad Vasculitis viral genome
[DOI] 10.1001/jamanetworkopen.2021.11369 PMC 바로가기 [Article Type] Research

Integrating longitudinal clinical laboratory tests with targeted proteomic and transcriptomic analyses reveal the landscape of host responses in COVID-19

Article

Published on 2021-06-082022-10-04
Journal: Cell Discovery [Category] 바이오마커, 변종, 진단, 치료제,