Maximum chest CT score is associated with progression to severe illness in patients with COVID-19: a retrospective study from Wuhan, China최대 흉부 CT 점수는 COVID-19 환자의 중증 질환 진행과 관련이 있습니다: 중국 우한의 후향적 연구Research Article Published on 2020-12-112022-09-01 Journal: BMC Infectious Diseases [Category] MERS, SARS, 진단, [키워드] 95% confidence interval association characteristic Chest computed tomography Chest CT chronic obstructive chronic obstructive pulmonary disease clinical parameter Clinical parameters Combination Computed tomography COPD coronavirus disease Coronavirus disease 2019 COVID-19 CT score demographic Deterioration diagnosed Disease progression electronic medical record electronic medical records enrolled evaluated Health Health crisis hospitalized patient hospitalized patients identify information Laboratory Limited male maximum medical records moderate Moderate COVID-19 multivariable logistic regression Multivariate regression obstructive pulmonary disease Older pandemic Patient Pneumonia Predictive Predictive value progressed progression pulmonary disease radiological receiver operating characteristic receiver operating characteristic curve Result retrospective Retrospective study risk factor Risk factors ROC severe disease single-center study supplementary material Symptom Symptoms were used Wuhan Wuhan, China [DOI] 10.1186/s12879-020-05683-3 PMC 바로가기 [Article Type] Research Article
Can the detection dog alert on COVID-19 positive persons by sniffing axillary sweat samples? A proof-of-concept study탐지견이 겨드랑이 땀 샘플을 스니핑하여 COVID-19 양성인 사람에게 경고할 수 있습니까? 개념 증명 연구Research Article Published on 2020-12-102022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, [키워드] 95% confidence interval Asymptomatic COVID-19 blinded Can chance Colon cancer conducted COVID-19 COVID-19 negative COVID-19 sample detection dogs detection dogs) evaluate Evidence FIVE France hospitals indication individual individuals involved limitation maximum olfactory Paris positive positive individual positive individuals positive sample Randomly ranged recruited SARS-CoV-2 PCR search and rescue Sweat symptomatic symptomatic COVID-19 testing protocols trials was collected [DOI] 10.1371/journal.pone.0243122 PMC 바로가기 [Article Type] Research Article
Epidemiological profile of SARS-CoV-2 among selected regions in Ghana: A cross-sectional retrospective study가나의 일부 지역에서 SARS-CoV-2의 역학 프로파일: 단면 후향적 연구Research Article Published on 2020-12-102022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] 95%CI age Analysis Anosmia association asymptomatic subject asymptomatic subjects average Chain Reaction Clinical presentations collected confirmation confirmed case conscious COVID-19 COVID-19 case COVID-19 cases cross-sectional deaths described epidemiological Features female females Gender greater highest individual Infection infection with SARS-CoV-2 IQR Laboratory majority male maximum middle minimum Ministry of Health Nasopharyngeal swab nasopharyngeal swabs pattern polymerase chain polymerase chain reaction presenting Prevalence professional provided Real-Time Reverse Transcription Polymerase Chain Reaction recorded reduction Region reproductive respiratory respiratory specimens Result Retrospective study reverse transcription reverse transcription polymerase chain reaction risk RT-PCR Saliva SARS-CoV-2 SARS-COV-2 infection selected socio-demographic specimen Spread sputum study population subject the disease the strongest trajectory Viral Viral load virus virus infection [DOI] 10.1371/journal.pone.0243711 PMC 바로가기 [Article Type] Research Article
Thromboembolic complications in critically ill COVID-19 patients are associated with impaired fibrinolysis중환자 COVID-19 환자의 혈전 색전증 합병증은 손상된 섬유소 용해와 관련이 있습니다Research Published on 2020-12-072022-09-12 Journal: Critical Care [Category] MERS, 진단, [키워드] anticoagulation Blood coagulation Coagulopathy Cohort Combination Complication Concentration contributing to Coronavirus 2019 COVID-19 COVID-19 patient COVID-19 patients Critically ill D-dimer D-dimers Evidence extrinsic coagulation system hypercoagulable Hypofibrinolysis identify intensity maximum mechanism morbidity and mortality Patient patients prothrombotic state reduction in required Result risk ROTEM Sensitivity and specificity single-center thromboembolic complication thromboembolic complications thromboembolic risk [DOI] 10.1186/s13054-020-03401-8 PMC 바로가기 [Article Type] Research
Estimating transmission dynamics and serial interval of the first wave of COVID-19 infections under different control measures: a statistical analysis in Tunisia from February 29 to May 5, 2020Research Article Published on 2020-12-022022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] accompany approach changes in collected data confidence Contact tracing coronavirus COVID-19 infection CrI Critical Describing First wave gamma distribution highlight illness onset information interval Intervention involved likelihood lockdown maximum measure National New Observatory outbreak pre-symptomatic reported Reproduction number response Result SARS-CoV-2 Serial interval Standard deviation statistical analysis statistical models the epidemic threshold Transmission Transmission dynamics transmission of SARS-CoV-2 Tunisia [DOI] 10.1186/s12879-020-05577-4 PMC 바로가기 [Article Type] Research Article
Rotational thromboelastometry results are associated with care level in COVID-19Observational Study Published on 2020-10-172022-10-04 Journal: Journal of Thrombosis and Thrombolysis [Category] MERS, SARS, 임상, [키워드] Admission age Blood Care cause clot coagulation tests Coagulopathy Comorbidity Conventional COVID-19 COVID-19 patient COVID-19 patients COVID-19 positive patients death diabetes disease severity effective eligible fibrinogen for inclusion healthy control high risk hospital hypertension indicate individual maximum median men Mild moderate disease organ Patient predict Prevalence prophylactic treatment Pulmonary embolism reported risk Severe COVID-19 pneumonia severely ill patient severity supplementary material Support the disease Thromboelastometry thromboembolic complication thrombosis thrombotic event two group variable Ventilation [DOI] 10.1007/s11239-020-02312-3 PMC 바로가기 [Article Type] Observational Study
The Efficacy of Famotidine in improvement of outcomes in Hospitalized COVID-19 Patients: A structured summary of a study protocol for a randomised controlled trial입원한 COVID-19 환자의 결과 개선에 대한 파모티딘의 효능: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-10-132022-08-13 Journal: Trials [Category] MERS, SARS, 임상, [키워드] Alanine Alanine transaminase alcoholism All participant All participants allergies allergy allocation approved ARMS aspartate Aspartate transaminase assigned assumption Bandar Abba Bandar Abbas baseline Blinding block randomization blood count Care Chronic kidney disease clearance clinical clinical trial clinical trials code Committee company comparator Comparator group complete blood count concealed control group control groups COVID-19 COVID-19 patient COVID-19 patients creatinine creatinine clearance criteria Dasatinib dialysis discharge dissemination dosage drug therapy electrocardiogram element eligibility criteria End-stage renal disease ethics committee Evidence evidence of excluded expected Famotidine G6PD Glucose Glucose 6 phosphate grouping groups Hepatitis hepatitis C Hospitalized Immunocompromised Immunocompromised patients Infection Intervention Kidney disease Lactate lactate dehydrogenase lead limit Liver disease Local lung infiltration maximum Medical Science Medical Sciences moderate need for dialysis Neratinib normal limit number objective online tool oral contraceptives outcome outcome assessor outcome assessors oxygen oxygen saturation Ozanimod participant Patient patients patients with COVID-19 Pazopanib PCR test pharmaceutical Pharmaceutical Company phosphate Placebo placebo-controlled porphyria positive Pregnancy protocol psoriasis random randomisation randomised randomised controlled trial randomized clinical trial Randomly randomly divided receive recruitment Registered registry renal renal disease renal failure reported Research question researcher respiration rate responsible Rilpivirine Sample size sample size calculation sequence sequence information single-blind Siponimod Standard study drug Study protocol subject submitted technology temperature the ethics committee therapy title Tizanidine transaminase Treatment treatment group Treatment protocol treatment protocols Trial registration two group two groups university Version website were measured written consent [DOI] 10.1186/s13063-020-04773-6 PMC 바로가기 [Article Type] Letter
Reliability and Repeatability Analysis of Indices to Measure Gait Deterioration in MS Patients during Prolonged Walking장기간 보행 중 다발성 경화증 환자의 보행 악화를 측정하기 위한 지표의 신뢰성 및 반복성 분석Article Published on 2020-09-062022-08-13 Journal: Sensors (Basel, Switzerland) [Category] 임상, [키워드] (range of motion) 6-min walking test analyzed asymmetry caused changes in clinical disability coefficient Coefficient of variation consequence correlated CoV Deterioration disability Effects evaluated Evolution Expanded Disability Status Scale fatigue FIVE Gait Gait deterioration Gait variability Good healthy subjects involved leads lower limb maximum measure motion multiple sclerosis nine outcome Patient Prolonged protocol Quantitative range of motion reliability repeatability ROM scale severity Standard deviation status subgroup subgroups suggested symmetry index synthetic indices Variability Variation walking were assessed were used [DOI] 10.3390/s20185063 PMC 바로가기 [Article Type] Article
Phylogenetic analysis of the first four SARS-CoV-2 cases in Chile칠레 최초 SARS-CoV-2 사례 4건의 계통발생 분석Article Published on 2020-09-012022-09-11 Journal: Journal of medical virology [Category] SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] Analysis Asia caused Chilean China Complete contribute coronavirus coronavirus disease COVID-19 disease Epidemics Europe Genome genome sequence group Infection information isolate isolates maximum measure Mutation New coronavirus pandemic Patient Phylogeny public health related virus SARS-CoV-2 similarities similarity Spread Transmission dynamics variant variants Viral viral variant virus viruses Wuhan [DOI] 10.1002/jmv.25797 PMC 바로가기 [Article Type] Article
A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protocol for a randomized controlled trial중환자실에 입원한 COVID-19 환자의 정맥 주사 멜라토닌의 효능과 안전성을 조사하기 위한 2상, 단일 센터, 이중 맹검, 무작위 위약 대조 시험(MelCOVID 연구): 연구 프로토콜의 구조화된 요약 무작위 대조 시험을 위해Letter Published on 2020-08-052022-08-13 Journal: Trials [Category] MERS, 임상, [키워드] 6 hours Acute hypoxemic respiratory failure addition Admission Adult patients adverse effect adverse event adverse events age allocation anticipated Autoimmune disease Biochemical parameters blinded Blinding blood gas blood gas analysis body weight C-reactive protein Caregivers carried chronic Chronic kidney disease clinical condition clinical development commercialization comparator compatible symptom compatible symptoms Complete completion computer conducted Confirmed Consent Control control arm control group COVID-19 COVID-19-associated thromboembolic phenomena Critically ill D-dimer daily dose Date determined by disease dissemination double-blind Efficacy and safety element enzyme EU Clinical Trial evaluate evaluate the effect exclusion criteria expected experimental arm experimental group failing organ failing organs family member ferritin Frequency gas analysis GFR greater hematologic Hemodialysis hypoxemic Hypoxemic respiratory failure ICU ICU admission impairment Inclusion inclusion criteria increase in inflammatory state Informed institutional protocols intensive care intensive care unit interleukin interleukin-6 intravenous Kidney disease legal guardian less liver enzymes maximum mechanical ventilation medical illness melatonin Mortality multi-organ failure normal range number objective Organ failure outcome parameters participant Patient patient condition patients with COVID-19 per day performed phase physician Placebo placebo-controlled randomized trial plasma Plasma levels positive RT-PCR Pregnancy pregnancy test Prevent procalcitonin Program protocol provided randomization randomization sequence Randomized Randomized controlled trial randomized placebo-controlled trial receive recruited recruitment reduced reduction Respiratory failure Sample size SARS-COV-2 infection SAS version 9.4 SAS version 9.4 statistical software secondary Secondary objectives Sequential Organ Failure Assessment severity single center single-center SOFA Spain Stage Standard-of-care statistical status study drug study group study groups study period Study protocol systemic inflammatory response Terminal surgical thromboembolic Treatment Trial Trial registration two-arm parallel Ventilator-free days website with COVID-19 worsening written Informed Consent [DOI] 10.1186/s13063-020-04632-4 PMC 바로가기 [Article Type] Letter