Population Pharmacokinetics of Remdesivir and GS-441524 in Hospitalized COVID-19 Patients
Observational Study
[키워드] 50% effective concentration
accumulates
clearance
clinically
collected
Concentration
coronavirus disease
covariate
COVID-19
COVID-19 patient
COVID-19 patients
daily dose
dependent on
described
distribution
dose
dosing regimen
Effectiveness
elimination half-life
evaluated
explain
glomerular filtration rate
GS-441524
Hospitalized
hospitalized COVID-19 patient
Hypoxemia
identify
IMPROVE
in vitro
metabolite
mixed-effects model
Patient
patients
pharmacokinetic
pharmacokinetics
plasma
plasma concentration
Population
Probability
reduced
Remdesivir
renal function
therapy
Treatment
Variability
Volume
was performed
[DOI] 10.1128/aac.00254-22 PMC 바로가기 [Article Type] Observational Study
[DOI] 10.1128/aac.00254-22 PMC 바로가기 [Article Type] Observational Study