More Than Just Attractive: How CCL2 Influences Myeloid Cell Behavior Beyond ChemotaxisReview Published on 2019-12-132023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] CCL2 chemokine function immune oncology macrophages myeloid cells polarization [DOI] 10.3389/fimmu.2019.02759 PMC 바로가기 [Article Type] Review
Tumors vs. Chronic Wounds: An Immune Cell’s PerspectiveReview Published on 2019-09-122023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] antiangiogenic immunotherapy endothelial cells macrophages myeloid cells Neutrophils tumor vessels wound repair [DOI] 10.3389/fimmu.2019.02178 PMC 바로가기 [Article Type] Review
Monocyte heterogeneity and functions in cancerReview Published on 2019-02-182023-08-30 Journal: Journal of leukocyte biology [Category] E형 간염, [키워드] Cancer Monocytes myeloid cells tumor microenvironment [DOI] 10.1002/JLB.4RI0818-311R PMC 바로가기 [Article Type] Review
Redefining Myeloid Cell Subsets in Murine SpleenOriginal Research Published on 2016-01-112023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] dendritic cells Monocytes myeloid cells spleen [DOI] 10.3389/fimmu.2015.00652 PMC 바로가기 [Article Type] Original Research
Interferon Regulatory Factor 8 Regulates Pathways for Antigen Presentation in Myeloid Cells and during Tuberculosis인터페론 조절 인자 8은 골수 세포 및 결핵 기간 동안 항원 제시 경로를 조절합니다Research Article Published on 2011-06-232022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] (major histocompatibility complex activate Activation allele Analysis Antigen presentation antigen processing Author binding binding site cellular pathway cellular pathways chromatin chromatin immunoprecipitation class Combination component Critical cytokine Defense dendritic cell dendritic cells differentiation early response endomembrane eQTLs expressed expression F2 Factor fixed functional Gene gene transcription GTPase GTPases histocompatibility complex Host–pathogen interaction identify IFNγ IL-12 IL12 immune response Infected Infection interferon gamma interferon regulatory factor interleukin intracellular pathogens intrinsic investigated IRF8 lipopolysaccharide LPS lung tissue lung tissues Lungs Macrophage macrophages major histocompatibility complex maturation member MHC mice Microarray Microarrays microbial motif mutant Mycobacterium tuberculosis myeloid myeloid cell myeloid cells ontogeny Pathogens pathway Pathways presentation priming progenitor cells promoter promoters Proteins pulmonary tuberculosis regulated Regulation represse required resistance to infection resistance to infections significantly Stimulation susceptible target transcript Transcription transcriptional treated Tuberculosis wild-type [DOI] 10.1371/journal.pgen.1002097 PMC 바로가기 [Article Type] Research Article
A Protective Role for ELR+ Chemokines during Acute Viral EncephalomyelitisResearch Article Published on 2009-11-062022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] abrogated absence acute viral infection Alter antibody Author blocking Blood Brain Central nervous system characterized chemokine Chemokine receptor chemotaxis clinical outcomes CNS compensatory mechanism consequence contribute CXCL1 CXCL2 CXCL5 CXCR2 Defense defined directional Encephalitis Encephalomyelitis Evidence expressed expressing expression facilitate functional highlight Host impair in vitro increased expression indicated Infection infiltration Inflammatory Injury inoculation involved leukocytes Ligand lymphocyte mice microbial infection Migration modulate Mortality mouse hepatitis virus myeloid cells neurotropic neutralization neutrophil Neutrophils pathogen poliomyelitis proinflammatory receptor recruitment reduced reduction required role shown Signaling survived T cell responses T cells transcript viral clearance viral infection viral replication viral-induced virus was determined [DOI] 10.1371/journal.ppat.1000648 PMC 바로가기 [Article Type] Research Article