AI-guided discovery of the invariant host response to viral pandemics
바이러스 전염병에 대한 불변 숙주 반응의 AI 유도 발견
Research Paper
[키워드] “cytokine storm”
abrogate
ACE2
acting
analyzed
Angiotensin converting enzyme (ACE)-2
Antiviral
antiviral agent
Apoptosis
approach
Artificial intelligence/machine learning
Boolean equivalent clusters
candidate drugs
cause
cell senescence
center
clinical
conserved
Cooperative
Coronavirus COVID-19
coronavirus disease
Coronavirus disease 2019
COVID-19
cytokine
Cytokine storm
dataset
determine
Diego
disease severity
EIDD-2801
elevated
ENCODE
entry of SARS-CoV-2
epithelial
facilitate
fatal COVID-19
fatal disease
fatality
finding
Fund
funding
hamster
Healthcare system
High-dose
host cells
Host immune response
host response
Human
IL15
IL15RA
immune response
immunologist
implicated
in viral
Interleukin 15 (IL15)
knowledge
limit
limits
LJI
lung
Lung alveoli
lung epithelial
Lungs
myeloid cell
myeloid cells
natural killer (NK) cells
Neutralizing antibodies
neutralizing antibody
NIH
NK cell
office
over
Pandemics
paradoxical
Patient
plasma
Plasma levels
President
Program
Quantitative
receptor
scientist
signature
STEM
stem cell
subset
supported
System
therapeutic
to define
transcriptomic
University of California
utility
Viral
virus
was used
[DOI] 10.1016/j.ebiom.2021.103390 PMC 바로가기 [Article Type] Research Paper
[DOI] 10.1016/j.ebiom.2021.103390 PMC 바로가기 [Article Type] Research Paper