no effect – Page 7 – Communicable Diseases Research

Has the COVID-19 Pandemic Affected Lay Beliefs about the Cause and Course of Mental Illness?

Article

Published on 2021-05-052022-10-29
Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS,

Mortality, viral clearance, and other clinical outcomes of hydroxychloroquine in COVID-19 patients: A systematic review and meta-analysis of randomized controlled trials

코로나19 환자에서 하이드록시클로로퀸의 사망률, 바이러스 제거 및 기타 임상 결과: 무작위 대조 시험의 체계적인 검토 및 메타 분석

Meta-Analysis

Published on 2021-05-012022-09-11
Journal: Clinical and translational science [Category] SARS, 임상,

[키워드] 95% CI 95% confidence interval adverse events certainty certainty of evidence Clinical outcome clinical outcomes coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection database effective Efficacy evaluated Evidence HCQ Hydroxychloroquine IMPROVE increased risk Lower Meta-analysis Mortality MOST no effect no significant effect not effective observational studies Patient patients with COVID-19 Prevent prevention of COVID-19 Prophylaxis Randomized controlled trial Randomized controlled trials RCT RCTs reducing mortality risk risk difference risk ratio safety profile screened searched systematic review Treatment Trial viral clearance
[DOI] 10.1111/cts.13001 PMC 바로가기 [Article Type] Meta-Analysis

Modest effects of dietary supplements during the COVID-19 pandemic: insights from 445 850 users of the COVID-19 Symptom Study app

Original Research

Published on 2021-04-192022-10-28
Journal: BMJ Nutrition, Prevention & Health [Category] COVID-19,

[키워드] 95% CI age association benefit BMI body mass index cohorts Community confounders Controlled trial COVID-19 dietary dietary supplement Effect Evidence fatty fatty acids female First wave General population groups individual investigated less lower risk men multivitamin no effect nutritional treatment objective omega-3 outcome measure pandemic participant positive Protective recommendation required Result reverse transcriptase PCR SARS-CoV-2 SARS-COV-2 infection self-reported information serology test setting Sex Stratification Support Swedish therapeutic USA Viral RNA Vitamin C vitamin D supplement women
[DOI] 10.1136/bmjnph-2021-000250 PMC 바로가기 [Article Type] Original Research

Endogenously Produced SARS-CoV-2 Specific IgG Antibodies May Have a Limited Impact on Clearing Nasal Shedding of Virus during Primary Infection in Humans

내인적으로 생성된 SARS-CoV-2 특이적 IgG 항체는 인간의 1차 감염 동안 바이러스의 비강 배출 제거에 제한적인 영향을 미칠 수 있음

Article

Published on 2021-03-202022-09-01
Journal: Viruses [Category] SARS, 진단,

[키워드] antibody antibody kinetics antigenic antigenic stimulation binding characterized Clearing Clinical severity ENhance Human IgG IgG and IgM IgG antibodies IgG level IgG levels IgM antibodies Immunity Impact Infection isotype Limited mathematical mathematical model Mathematical models Mitigation nasal passage nasal passages natural infection neutralization no effect occur Primary infection production rate resulting SARS-CoV-2 SARS-CoV-2 viral severe disease severity shedding Specific specific IgG antibodies specific IgG antibody specific neutralizing antibodies specific neutralizing antibody symptom onset therapeutic purposes Trigger triggers vaccination Viral viral clearance viral dynamics virus while
[DOI] 10.3390/v13030516 PMC 바로가기 [Article Type] Article

Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Random Sample of Inhabitants of the Katowice Region, Poland

폴란드 카토비체 지역 주민의 무작위 표본에서 항-SARS-CoV-2 항체의 혈청유병률

Article

Published on 2021-03-192022-09-12
Journal: International Journal of Environmental Research an [Category] SARS, 진단,

[키워드] 95% CI age anti-SARS-CoV-2 IgG antibody Arterial hypertension chronic disease Chronic diseases Contact contact with COVID-19 COVID-19 patient diabetes diagnose diagnoses estimate European Fever General population hypertension IgG IgG and IgM IgG test IgG/IgM seroprevalence IgM IgM antibodies IgM antibody IgM test implementation knowledge less Loss of Smell loss of smell/taste no effect past performed Poland positive Prevalence prevalent quarantine questionnaire questionnaire examination random Random sample reason reason for Region representative sample rheumatologic disorders Risk factors Sample SARS-CoV-2 SARS-COV-2 infection second wave Seropositivity Seroprevalence significantly statistically subject subjects Symptom the epidemic
[DOI] 10.3390/ijerph18063188 PMC 바로가기 [Article Type] Article

Effectiveness of Community-Delivered Functional Power Training Program for Frail and Pre-frail Community-Dwelling Older Adults: a Randomized Controlled Study

Randomized Controlled Trial

Published on 2021-03-192022-10-04
Journal: Prevention science : the official journal of the S [Category] MERS, SARS, 임상,

COVID-19 Evidence Accelerator: A parallel analysis to describe the use of Hydroxychloroquine with or without Azithromycin among hospitalized COVID-19 patients

COVID-19 Evidence Accelerator: 입원한 COVID-19 환자에서 아지트로마이신을 포함하거나 포함하지 않은 하이드록시클로로퀸의 사용을 설명하기 위한 병렬 분석

Research Article

Published on 2021-03-172022-09-10
Journal: PLoS ONE [Category] SARS, 치료제,

[키워드] Accelerator adjust adverse event adverse events Analysis Azithromycin best collaboration Combination COVID-19 COVID-19 pandemic Cox proportional hazard Cox proportional hazards models Data science data set data sets Effectiveness EHR Electronic health record elevated Epidemiology Evidence examined FDA foundation frequencies Friend friends health record health system hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitalized patients Hydroxychloroquine Mortality no effect Patient pharmaceutical intervention Pharmaceutical interventions proportional hazards models Regulatory Research Result risk Seven significantly treat treated Treatment treatment group treatment groups treatment of COVID-19 use of hydroxychloroquine were used
[DOI] 10.1371/journal.pone.0248128 PMC 바로가기 [Article Type] Research Article

The Characterization of Disease Severity Associated IgG Subclasses Response in COVID-19 Patients

COVID-19 환자의 질병 중증도 관련 IgG 하위 분류 반응의 특성화

Immunology

Published on 2021-03-042022-09-11
Journal: Frontiers in Immunology [Category] SARS, 진단, 치료법,

[키워드] age analyzed antibodies Antibody Response Antigen Asymptomatic COVID-19 characterization chemokines Clinical outcome Comorbidities Comorbidity coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 patient cytokine cytokine production Cytokines disease disease severity dysregulated immune response dysregulated immune responses Evidence had no hospitalized patient Host immune response Ig isotype Ig isotypes IgG IgG subclasse IgG subclasses IgG1 IgG3 IL-1β immune responses Immunoglobulin Increasing isotypes Mild moderate Multiple multiple cytokines NAb activity Nasopharyngeal swab negative correlation neutralizing antibody no effect nucleocapsid protein Patient positively correlated Protein RBD Receptor binding domain response SARS-CoV-2 serum severe cases severity Sex significantly T cell T cell response T cell responses Viral Viral load was related
[DOI] 10.3389/fimmu.2021.632814 PMC 바로가기 [Article Type] Immunology

A Bayesian reanalysis of the effects of hydroxychloroquine and azithromycin on viral carriage in patients with COVID-19

COVID-19 환자의 바이러스 운반에 대한 하이드록시클로로퀸과 아지트로마이신의 영향에 대한 베이지안 재분석

Comparative Study

Published on 2021-02-192022-09-10
Journal: PLoS ONE [Category] MERS, 변종, 진단, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analyses applied assumed assumption Azithromycin Bayesian case sery coronavirus dual Effect effective Effects Evidence examined exclusion HCQ Hydroxychloroquine include Inclusion Interpretation moderate monotherapy no effect paper Patient patients patients with COVID-19 performed positive raise ranged reducing reduction reported respiratory robustness SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 statistical the patient These data Treatment upper respiratory tract variant variants Viral Viral load virus were excluded
[DOI] 10.1371/journal.pone.0245048 PMC 바로가기 [Article Type] Comparative Study

Repurposed Antiviral Drugs for Covid-19 – Interim WHO Solidarity Trial Results

Covid-19에 대한 용도 변경 항바이러스 약물 - WHO 연대 실험 잠정 결과

Randomized Controlled Trial

Published on 2021-02-112022-09-11
Journal: The New England Journal of Medicine [Category] Fulltext, MERS, 임상, 치료제,

[키워드] (rate ratio 28-day mortality 95% CI 95% confidence interval adherence age Analysis antiviral drug antiviral drugs assigned calculated Care coronavirus disease Coronavirus disease 2019 death drug drug regimen examined FIVE group Health Organization hospital Hospital stay Hospitalization hospitalized patient hospitalized patients Hydroxychloroquine in-hospital mortality indicated Inpatient Inpatients intention-to-treat interferon interferon beta Interferon beta-1a Interim interquartile range ISRCTN registry Kaplan-Meier Local Lopinavir mechanical ventilation median Mortality no effect occurred open overall mortality Pairwise comparison Patient patients hospitalized randomization Randomly rate ratio rate ratios receive receiving reduced regimen Remdesivir reported Result Solidarity trial Standard of care status Stratification the patient Treatment Trial Ventilation WHO World Health Organization
[DOI] 10.1056/NEJMoa2023184 PMC 바로가기 [Article Type] Randomized Controlled Trial