COVID-19 Diagnosis: Current and Future TechniquesReview Published on 2021-12-152023-06-19 Journal: International journal of biological macromolecules [Category] MERS, SARS, [키워드] biosensors COVID-19 CRISPR-Cas Diagnosis nanobodies nucleic acids serology [DOI] 10.1016/j.ijbiomac.2021.11.016 PMC 바로가기 [Article Type] Review
SARS-CoV-2 and Variant Diagnostic Testing Approaches in the United States미국에서 SARS-COV-2 및 변형 진단 테스트 접근법Review Published on 2021-12-132022-09-01 Journal: Viruses [Category] SARS, 변종, 진단, 치료기술, [키워드] antibody Antibody Response Antibody responses Antigen approach approval attainment B.1.1.529 Characteristics COVID-19 detect diagnose diagnostic diagnostic testing Diversity Emergency use authorization EUA FDA finding Infection infection with SARS-CoV-2 information Laboratory Multiple nucleic acids omicron PCR performed platform provide reagent reagents recent recent findings review SARS-CoV-2 significantly subsequent Supply chain Support Testing the United State United States variant variants Viral Viral variants [DOI] 10.3390/v13122492 PMC 바로가기 [Article Type] Review
CRISPR-cas13 enzymology rapidly detects SARS-CoV-2 fragments in a clinical settingCRISPR-cas13 효소는 임상 환경에서 SARS-CoV-2 단편을 빠르게 감지합니다.Article Published on 2021-12-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 변종, 치료기술, 치료제, [키워드] 95% CI Accuracy approach Cas13 enzymology Clinical diagnosis clinical samples clinical setting conserved consumables controls COVID-19 COVID-19 patient CRISPR CRISPR technology CRISPR-Ca detect diagnosed diagnostics EUA evaluate evaluated expected Fluorescence Fluorescence readout form Genome highlight Increased Infectious disease isolates N gene nucleic acid Nucleic acid detection nucleic acids ORF1 ORF1ab gene positive protocol RNase P RT-LAMP RT-PCR assay RT-PCR assays SARS-CoV-2 selected Specific target thresholds triggered Vaccine variant viral loads [DOI] 10.1016/j.jcv.2021.105019 PMC 바로가기 [Article Type] Article
One-pot pre-coated interface proximity extension assay for ultrasensitive co-detection of anti-SARS-CoV-2 antibodies and viral RNA항 SARS-CoV-2 항체 및 바이러스 RNA의 초민감성 공동 검출을 위한 원 포트 사전 코팅된 인터페이스 근접 확장 분석Article Published on 2021-12-012022-09-11 Journal: Biosensors & bioelectronics [Category] MERS, SARS, 진단, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplified anti-SARS-CoV-2 antibody antibody Antigen biological sample biological samples Chain Reaction Co-detection coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 detect Detection limit Diagnosis diagnostics disease course e genes equipment extension facilitate fluorescent IgG and IgM immunoassay in vitro independent management multiplex nucleic acid nucleic acids nucleocapsid nucleocapsid protein offer oligonucleotides pair pandemic performed platform polymerase chain reaction Pre-coated solid interface probes Protein proximity extension assay RdRP respiratory Reverse transcription-polymerase chain reaction RNA RNA fragment SARS-CoV-2 serum severe acute respiratory syndrome Coronavirus specific antibodies TaqMan Viral viral nucleic acid viral nucleic acids Viral RNA [DOI] 10.1016/j.bios.2021.113535 PMC 바로가기 [Article Type] Article
Production of full-length SARS-CoV-2 nucleocapsid protein from Escherichia coli optimized by native hydrophobic interaction chromatography hyphenated to multi-angle light scattering detection다각도 광산란 검출에 하이픈으로 연결된 천연 소수성 상호작용 크로마토그래피에 의해 최적화된 대장균으로부터 전장 SARS-CoV-2 뉴클레오캡시드 단백질 생산Article Published on 2021-12-012022-09-11 Journal: Talanta [Category] SARS, 치료기술, 치료법, 치료제, [키워드] abundantly expressed acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis analytical method Cell cell lysis chaperone Chromatography complementary coronavirus cpCasp2‐based platform fusion protein process (CASPON technology). Critical diagnostic dimerized downstream Downstream processing (DSP) DSP E. coli enhanced enzyme-linked immunosorbent enzyme-linked immunosorbent assay Escherichia coli explained fermentation fraction full-length SARS-CoV-2 fusion protein host cell hydrophobic Hydrophobic interaction chromatography-multi-angle light scattering (HIC-MALS) Infection information Interaction life cycle mass spectrometry minor molecular MONITOR novel Novel coronavirus Novel coronavirus (termed SARS-CoV-2) Nuclease nucleic acids nucleocapsid protein nucleoprotein peptide platform produced Production Protein protein expression purification purified purity resolving power SARS-CoV-2 scattering SEC selectivity sequence severe acute respiratory syndrome Coronavirus target protein Treatment variable viral life cycle was used were expressed yield [DOI] 10.1016/j.talanta.2021.122691 PMC 바로가기 [Article Type] Article
The crosstalk between viral RNA- and DNA-sensing mechanisms바이러스 RNA 및 DNA 감지 메커니즘 간의 누화Review Published on 2021-12-012022-09-11 Journal: Cellular and Molecular Life Sciences [Category] SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] adaptors amplify Antiviral COVID-19 Crosstalk Cytokines cytosolic detect Diseases DNA DNA and RNA DNA sensing endosomal highlight Host Human induce Infection innate immune system Innate immunity innate response interferon-stimulated gene interferon-stimulated genes mechanism nucleic acids overlap pandemic disease proinflammatory cytokines receptor recognize restrict RNA RNA sensing significantly Type type I interferon Viral diseases viral infection viral infections viral nucleic acid viral nucleic acids Viral RNA virus [DOI] 10.1007/s00018-021-04001-7 PMC 바로가기 [Article Type] Review
Application of Stem Cell-Derived Extracellular Vesicles as an Innovative Theranostics in Microbial DiseasesMicrobiology Published on 2021-11-302022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] acute respiratory syndrome antimicrobial agents application Bacteria bacterial EVs biogenesis cell types clinical complication component coronavirus death demonstrated described develop diagnostic disease early diagnosis Efficiency Escherichia coli EVs Extracellular vesicles HBV HCV Hepatitis B virus hepatitis C virus HIV Human immunodeficiency virus Impact Infectious disease lipids mechanism microbes microbial MSC-derived EVs nucleic acids Organisms Particle pathogen pathogenic microorganism peptides physiological platform produced Proteins responsible RNA SARS-CoV-2 Staphylococcus aureus STEM stem cell stem cells Therapeutic approach Therapeutic strategies therapy translation Treatment Vesicle Viral EVs virus [DOI] 10.3389/fmicb.2021.785856 PMC 바로가기 [Article Type] Microbiology
Structure-Function Characteristics of SARS-CoV-2 Proteases and Their Potential Inhibitors from Microbial SourcesReview Published on 2021-11-302022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] 3-chymotrypsin-like protease 3CLpro Antiviral Bacteria candidate caused Community Compound coronavirus 2 COVID-19 COVID-19 pandemic cysteine protease drug drug design drug target expand function fungi Health HIV protease inhibitor Host Infection information inhibitor inhibitors less microbial Modification nucleic acids nucleosides nucleotides Papain-like protease platform PLPro Potential protease Proteases Protein protein synthesis reported researcher resource respiratory RNA SARS-CoV-2 SARS-CoV-2 protease SARS-CoV-2 proteases SARS-CoV-2 viral SARS-CoV2 Source Spread structures suggested the SARS-CoV-2 Transcription translation Treatment urgency virus virus replication while with COVID-19 [DOI] 10.3390/microorganisms9122481 PMC 바로가기 [Article Type] Review
Fabrication of a paper-based colorimetric molecular test for SARS-CoV-2Method Article Published on 2021-11-202022-10-30 Journal: MethodsX [Category] COVID-19, [키워드] Abstract acute respiratory syndrome can be used caused colorimetric LAMP Community complex coronavirus detect diagnostic testing diagnostics fabrication Image isothermal amplification key factor Microfluidic paper-based analytical devices molecular test nucleic acids pandemic Paper-based diagnostics pathogen platform POC point-of-care primer sets Primers public health reporter response RT-LAMP SARS-CoV-2 virus transmission [DOI] 10.1016/j.mex.2021.101586 PMC 바로가기 [Article Type] Method Article
The Potential Contribution of Biopolymeric Particles in Lung Tissue Regeneration of COVID-19 PatientsReview Published on 2021-11-202022-10-28 Journal: The British journal of oral & maxillofacial surger [Category] COVID-19, [키워드] airway epithelial cell antibodies attack biopolymeric nanoparticles biopolymeric scaffolds Cell chemotherapeutic drugs components COVID-19 COVID-19 illness creating diagnostic effective example Gas exchange highlight Inflammation lung lung cell lung cells lung tissue nucleic acids organ Particle Potential Proteins regeneration resulting stem cells Symptom These cells tissue regeneration transfer Treatment Vaccines with COVID-19 [DOI] 10.3390/polym13224011 PMC 바로가기 [Article Type] Review