The interferon landscape along the respiratory tract impacts the severity of COVID-19
호흡기를 따라 나타나는 인터페론 풍경은 COVID-19의 심각성에 영향을 미칩니다
Article
[키워드] Abstract
acute respiratory syndrome
age
airways
anatomical
Apoptosis
cell death
characterized
coronavirus
coronavirus disease
COVID-19
COVID-19 patient
critical patient
dendritic cell
disease
disease risk
disease severity
elevated
epithelial cell
Express
expression
IFN
IFN-I
IFN-III
IFN-stimulated genes
IFN-λ1
ill patient
immune
Impact
in-depth analysis
interferon
interferons (IFNs
ISG
lower airway
lung
Mild
p53
Pathologies
pathology
pathway
Patient
pattern recognition receptor
Production
proliferation
PROTECT
Protective
reduced
reduction in
respiratory tract
reveal
SARS-CoV-2
SARS-CoV-2 viral
SARS-CoV-2-infected patient
severe COVID-19
severity
severity of COVID-19
subject
Transcription
type I
Type I IFN
type III
Type III IFN
upper airway
upper respiratory tract
viral burden
Viral load
[DOI] 10.1016/j.cell.2021.08.016 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.cell.2021.08.016 PMC 바로가기 [Article Type] Article