A blood atlas of COVID-19 defines hallmarks of disease severity and specificityArticle Published on 2022-03-032023-06-14 Journal: Cell [Category] MERS, SARS, [키워드] Blood coronavirus COVID-19 epigenetics immune Multi-omics Personalized medicine proteomics SARS-CoV-2 transcriptomics [DOI] 10.1016/j.cell.2022.01.012 PMC 바로가기
Multi-Cellular Immunological Interactions Associated With COVID-19 InfectionsArticle Published on 2022-02-242023-06-18 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, [키워드] biological complexity COVID-19 cutoff-free error prevention multi-cellularity Pattern recognition Personalized medicine personalized methods [DOI] 10.3389/fimmu.2022.794006 PMC 바로가기
HLA-C*04:01 Affects HLA Class I Heterozygosity and Predicted Affinity to SARS-CoV-2 Peptides, and in Combination With Age and Sex of Armenian Patients Contributes to COVID-19 SeverityHLA-C*04:01 SARS-CoV-2 펩티드에 대한 HLA 클래스 I 이형접합 및 예측된 친화도에 영향을 미치고 아르메니아 환자의 연령 및 성별과 함께 COVID-19 심각도에 기여Immunology Published on 2022-02-032022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] 95% CI advanced age affinity affinity to SARS-CoV-2 age Antigen Armenian population Armenians association Asymptomatic Asymptomatic COVID-19 AUC carriers change class contribute contributed Control COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 severity COVID-19 susceptibility decrease deficiency demographic variable disease severity disease symptom distribution dose-dependent manner Effect examined Frequency Genotype Health heterozygosity HLA HLA allele HLA classical genes HLA-B HLA-B*51:01 HLA-C HLA-C*04:01 HLA-C*04:01 allele HLA-I heterozygosity homozygous Hospitalization host immunity incidence Infection Interaction leukocyte loci Male sex outcome Patient patients peptide Personalized medicine predicted Prevalence Protective provided recognize risk SARS-CoV-2 SARS-CoV-2 coronavirus SARS-CoV-2 peptides severe COVID-19 severity severity risk modelling Sex significant increase significantly subgroup the disease the SARS-CoV-2 translated Variability [DOI] 10.3389/fimmu.2022.769900 PMC 바로가기 [Article Type] Immunology
Digital Transformation in Personalized Medicine with Artificial Intelligence and the Internet of Medical ThingsReview Published on 2022-02-012023-07-06 Journal: Omics : a journal of integrative biology [Category] COVID19(2023년), [키워드] artificial intelligence deep phenotyping Digital health internet of medical things machine learning Personalized medicine theranostics [DOI] 10.1089/omi.2021.0037 [Article Type] Review
Horizon Scanning: Teaching Genomics and Personalized Medicine in the Digital AgeArticle Published on 2022-02-012023-07-06 Journal: Omics : a journal of integrative biology [Category] COVID19(2023년), [키워드] Digital health e-learning courses genomic education Personalized medicine portable molecular biology laboratory public engagement. [DOI] 10.1089/omi.2021.0119
Public R&D Projects-Based Investment and Collaboration Framework for an Overarching South Korean National Strategy of Personalized MedicineArticle Published on 2022-01-242022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] accelerated analyzed Cluster collaboration comparable COVID-19 pandemic creating dimension eight framework Government government investment healthcare implementation information Investment Korean Medicine National organization Personalized medicine provided Public public health public R&D project Region regions Research South Strategy [DOI] 10.3390/ijerph19031291 PMC 바로가기 [Article Type] Article
Insights Into the Changing Landscape of Coronavirus Disease 2019Cellular and Infection Microbiology Published on 2022-01-102022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome caused Changing China clinical manifestation confirmed case connection contagious coronavirus Coronavirus disease 2019 COVID epidemiology COVID origin COVID treatment COVID-19 death disease Epidemiology genetics global pandemic highlight Infectious disease insight landscape management pandemic pathology Personalized medicine reported SARS-CoV-2 targeted therapy Treatment World Health Organization Wuhan [DOI] 10.3389/fcimb.2021.761521 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Meeting the needs of patients with ultrarare diseasesReview article Published on 2022-01-072022-10-05 Journal: Trends in molecular medicine [Category] 비임상, [키워드] approaches diagnosed Diagnosis disease Genetic genomic diagnosis Health care system Human genome long-term treatment majority meeting Patient patients personalized antisense oligonucleotide (ASO) treatments Personalized medicine phenotype problem quality systems sequenced the disease ultrarare mutations unique [DOI] 10.1016/j.molmed.2021.12.002 [Article Type] Review article
Exploring AyuGenomics approach for understanding COVID-19 predisposition and progressionReview article Published on 2022-01-012022-10-05 Journal: Journal of Ayurveda and Integrative Medicine [Category] 신약개발, 유전자 메커니즘, [키워드] allele Antigen approach AyuGenomics Ayurveda clinical evaluation clinically COVID-19 COVID-19 infection described drug response enzyme Genes Genetic Genetic predisposition Genetic variant genomic Genomics HLA HLA-DR hypothese identifying immune response imperative individual integrative medicine leukocyte management offer Personalized medicine phenotype phenotypic phenotypic variant populations predict predisposition progression protease recent reported SARS-CoV-2 serine 2 susceptibility tested Therapeutic strategies transmembrane variant variations [DOI] 10.1016/j.jaim.2021.06.003 [Article Type] Review article
Warfarin Pharmacogenomics for Precision Medicine in Real-Life Clinical Practice in Southern Africa: Harnessing 73 Variants in 29 PharmacogenesResearch Article Published on 2022-01-012023-07-02 Journal: Omics : a journal of integrative biology [Category] SARS, [키워드] Africa drug transporters gene-drug interaction Genetic variation Personalized medicine pharmacogenomics Warfarin [DOI] 10.1089/omi.2021.0199 PMC 바로가기 [Article Type] Research Article