Delivering Urgent Care Using Telemedicine: Insights from Experienced Clinicians at Academic Medical CentersOriginal Research Published on 2021-12-172022-10-31 Journal: Journal of General Internal Medicine [Category] Coronavirus, MERS, SARS, [키워드] added Analysis approach Care center clinician coding communication conducted continuum COVID-19 pandemic effective facilitator Factor female fraction Health help improvement information insight majority managing objective occur Patient Perspective Practitioner preserved provided provider experiences Result routine clinical practice Support Telemedicine tension understanding urgent care USA Workplace [DOI] 10.1007/s11606-020-06395-9 PMC 바로가기 [Article Type] Original Research
Insights into the Binding of Receptor-Binding Domain (RBD) of SARS-CoV-2 Wild Type and B.1.620 Variant with hACE2 Using Molecular Docking and Simulation ApproachesArticle Published on 2021-12-102022-10-28 Journal: Biology [Category] COVID-19, [키워드] ACE2 affected Alter Analysis approaches atomic B.1.620 bind binding binding energy binding free energy can be used caused changes complex complexes conformational determine docking docking score domain drug E484K mutation Europe feature free energy hACE2 Hydrogen bond insight Interaction molecular Mutation preserved protein complex provide RBD remained reported required S477N Salt Bridge SARS-CoV-2 simple Simulation stability substitutions the binding affinity the RBD therapeutic strategy Type variant variants Variation wild type wild-type [DOI] 10.3390/biology10121310 PMC 바로가기 [Article Type] Article
Characteristics and outcomes of hospitalized patients with cardiovascular complications of COVID-19Original Article Published on 2021-12-062022-10-30 Journal: Journal of Cardiovascular and Thoracic Research [Category] COVID-19, [키워드] acute coronary syndromes Admission all-cause mortality arrhythmia cardiovascular complication cardiovascular diseases Care cerebrovascular accident Clinical outcome cohort study Complication complications concerning COVID-19 COVID-19 patients CV complication CV complications diastolic died discharge disease disease severity dysfunction Ejection fraction elevated enrolled form greater heart failure hospital discharge Hospitalization hospitalized patient increased mortality independent predictor interferon IQR median age Mortality Myocardial infarction myocarditis N-terminal occurred outcome Patient patients preserved prevalent pro-B-type natriuretic peptide proportion retrospective risk significantly higher single-center study population thrombosis troponin I ventricular with COVID-19 yielding [DOI] 10.34172/jcvtr.2021.53 PMC 바로가기 [Article Type] Original Article
A COVID-19 pandemic-specific, structured care process for peritoneal dialysis patients facilitated by telemedicine: Therapy continuity, prevention, and complications managementObservational Study Published on 2021-12-012022-10-05 Journal: Therapeutic apheresis and dialysis : official peer [Category] SARS, 임상, [키워드] Care care process collected Complication complications Coronavirus disease 2019 country COVID-19 COVID-19 transmission dialysis facilitated Follow-up follow-up period healthcare Hemodialysis implementation initial initiated management outcome pandemic Patient patients Peritoneal dialysis physical distancing measure positive preserved Prevent protocol Registered risk Seven System Telemedicine tested the patient therapy transfer treated were given [DOI] 10.1111/1744-9987.13635 PMC 바로가기 [Article Type] Observational Study
An immunodominant NP 105–113 -B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 diseaseArticle Published on 2021-12-012022-10-04 Journal: Nature Immunology [Category] Fulltext, SARS, 유전자 메커니즘, 임상, 치료기술, 치료법, [키워드] Antiviral antiviral efficacy association Beta CD8 clone Control convalescent correlated COVID-19 disease COVID-19 severity CTL CTLs cytotoxic T lymphocyte Delta demonstrated disease severity dominant functional Gamma immune memory immunodominant Immunological memory in vitro Inclusion Infection less performed Postinfection precursors preserved progression reduced SARS-COV-2 infection SARS-CoV-2-infected individuals Sequencing severe COVID-19 disease single-cell T cell T cell receptor T cell response targets the SARS-CoV-2 Transcriptome Vaccine Vaccine design variants Victoria viral infection viral replication with mild disease [DOI] 10.1038/s41590-021-01084-z PMC 바로가기 [Article Type] Article
Myotonic dystrophy type 1 as a major risk factor for severe COVID-19?Observational Study Published on 2021-12-012022-10-05 Journal: Acta neurologica Belgica [Category] SARS, 임상, [키워드] Antibiotics Care case sery clinical Clinical course Comorbidities coronavirus disease COVID-19 determinant Diabetes Mellitus died disease functional Health care system high risk high-risk population hospitalized patient Hydroxychloroquine Infectious disease Intensive myotonic Myotonic dystrophy Neuromuscular Neuromuscular disorders nocturnal Non-invasive obese Outbreaks outcome Oxygen therapy pandemic Patient positive pressure ventilation preserved receiving risk factor SARS-CoV-2 severe disease Steinert’s disease. supportive care to define Trial Two patient unique ventilatory support [DOI] 10.1007/s13760-020-01514-z PMC 바로가기 [Article Type] Observational Study
Antibodies specific to SARS-CoV-2 proteins N, S and E in COVID-19 patients in the normal population and in historical samples정상 인구 및 과거 샘플의 COVID-19 환자에서 SARS-CoV-2 단백질 N, S 및 E에 특이적인 항체Animal Published on 2021-11-242022-09-10 Journal: The Journal of General Virology [Category] MERS, SARS, 진단, 치료법, [키워드] acquired immunity acute respiratory syndrome acute respiratory syndrome coronavirus analysed antibodies antibody Antibody Response can not circulation coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient diagnostic domain envelope protein epidemiological healthy IgA IgA levels IgG IgG level immune response immune responses immunology Infection inhibit SARS-CoV-2 Kinetics nucleocapsid protein other coronavirus other coronaviruses pandemic Patient preserved Protective protective role Recognition respiratory SARS-CoV-2 SARS-CoV-2 protein sera severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spike protein Spread target the SARS-CoV-2 Treatment virus virus-neutralizing [DOI] 10.1099/jgv.0.001692 PMC 바로가기 [Article Type] Animal
Feasibility of Prehospital Emergency Anesthesia in the Cabin of an AW169 Helicopter Wearing Personal Protective Equipment During Coronavirus Disease 2019코로나바이러스 질병 2019 동안 개인 보호 장비를 착용한 AW169 헬리콥터의 객실에서 병원 전 응급 마취의 가능성Article Published on 2021-11-012022-09-11 Journal: Air medical journal [Category] SARS, 변종, [키워드] adoption aerosol-generating procedure aerosol-generating procedures AGP AGPs Air ambulance aircraft Ambulance Anesthesia benefit clinician communication complications Critical Critical care direct laryngoscopy Emergency emergency medical service Endotracheal intubation equipment feasibility gown had no Helicopter Intervention intubate intubation medical service medical services mitigate Patient patient safety performed Personal protective equipment PPE prehospital preserved questionnaire reported Research scenario sequence significantly variant wearing [DOI] 10.1016/j.amj.2021.08.008 PMC 바로가기 [Article Type] Article
The Spectrum of Manifestations of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV2) Infection in Children: What We Can Learn From Multisystem Inflammatory Syndrome in Children (MIS-C)Medicine Published on 2021-10-282022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] absence acute SARS-CoV-2 infection ADE antibody Asymptomatic carrier Can capillary cardiac function children children with MIS-C clinically collected coronavirus disease 19 COVID-19 Critical defined definitive diagnosis develop disease etiology Evidence feature Fever heart failure hemodynamic hemophagocytic lymphohistiocytosis HLH Hospitalization hyperinflammation Hyperinflammatory immunological immunological profile Infection Inflammatory biomarker Inflammatory response Interpretation Isolation Laboratory manifestation mechanism MIS-C molecular Myocardial inflammation myocarditis observation occur organ Pathogenesis Patient patients pediatric positive serology preserved profiles respiratory responsible SARS-CoV2 SARSCoV-2 Severe infection Shock Spectrum symptomatic syndrome the disease toxic TSS Viral load [DOI] 10.3389/fmed.2021.747190 PMC 바로가기 [Article Type] Medicine
Persistence of Antibody Responses to the SARS-CoV-2 in Dialysis Patients and Renal Transplant Recipients Recovered from COVID-19Article Published on 2021-10-062022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] antibody antibody persistence Antibody titer association average circulating Clinical severity coronavirus disease COVID COVID-19 dialysis disease evaluated form healthcare worker Hemodialysis heterogeneous humoral immune response Humoral response IgG immune function immune response Immunocompromised immunodepressed patients infection rate kidney transplant recipients Laboratory maintain Neutralizing antibodies neutralizing antibody not significant occurred pathology Patient patients persistence preserved Protective antibody quantitative determination reached recipient recovered renal Renal transplant recipients response S1/S2 SARS-CoV-2 SARS-CoV-2 S1/S2 subject subjects the SARS-CoV-2 threshold Transplant Variability weakened [DOI] 10.3390/pathogens10101289 PMC 바로가기 [Article Type] Article