protein structure

[키워드] ACE2 ACE2 variants allelic angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 Asian assumed bilateral pneumonia binding Cell changes Clinical severity clinical variability Cluster Cohort contribute Control coronavirus coronavirus disease Coronavirus disease-19 COVID-19 described disease disease susceptibility Endemic enzyme European country FIVE genetic background Genome assembly algorithms host protease host proteases host receptor human-to-human transmission individual Infection initial interfere internalization interstitial Italian Italian population Italy Missense network NIG Novel coronavirus p value Patient patients Pneumonia predicted preventive measure preventive measures Protein Protein binding protein stability protein structure Rare variants reason reason for risk Risk assessment SARS-CoV-2 SARS-CoV-2 spike protein severity shown Spike protein Spread statistically significant susceptibility Taking therapeutic options underlie Variability variant variants viral infection WES whole-exome sequencing with COVID-19 Wuhan Wuhan, China
[DOI] 10.1038/s41431-020-0691-z PMC 바로가기 [Article Type] Article