Impact of rapid multiplex PCR on management of antibiotic therapy in COVID-19-positive patients hospitalized in intensive care unitObservational Study Published on 2021-10-012022-10-05 Journal: European Journal of Clinical Microbiology & Infect [Category] SARS, 임상, [키워드] Analysis antibiotic antibiotic stewardship Antibiotic therapy Antibiotics Coinfection COVID-19 COVID-19 patient Diagnosis evaluated help ICU patient Impact IMPROVE initiated intensive care management Multiplex PCR Panel patients hospitalized Rapid remained respiratory sample Sensitivity and specificity superinfection Withdrawal [DOI] 10.1007/s10096-021-04213-6 PMC 바로가기 [Article Type] Observational Study
Detection of respiratory pathogens by application of multiplex PCR panel during early period of COVID-19 pandemic in a tertiary hospital in Central TaiwanResearch article Published on 2021-10-012022-10-05 Journal: Journal of microbiology, immunology, and infection [Category] 치료기술, [키워드] Adults age analyzed Atypical pathogen children China clinical presentation Cohort collected conducted COVID-19 pandemic detect detection detection rate Epidemiology group hospital Human IMPROVE incidence Infection less multiplex Multiplex PCR Mycoplasma pneumoniae nucleic acid pathogen Pathogens polymerase chain positive rate predominant real time respiratory respiratory infections respiratory pathogen Respiratory pathogens respiratory sample respiratory tract infection Result retrospective cohort study Taiwan tested university virus [DOI] 10.1016/j.jmii.2021.09.011 [Article Type] Research article
Role of Nucleocapsid Protein Antigen Detection for Safe End of Isolation of SARS-CoV-2 Infected Patients with Long Persistence of Viral RNA in Respiratory SamplesArticle Published on 2021-09-072022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] absence addition antigen test Cell culture concomitant disease Concordance criterion defined detection diagnosed Diagnosis End evaluate evaluated Immunocompromised in some Infection Infectious virus infective Isolation isolation and discharge recommendations Long Nasopharyngeal swab negative and positive Patient persistence predict resolution of symptoms respiratory respiratory sample respiratory tract RNA role RT-PCR Safe Sample SARS-CoV-2 SARS-COV-2 infection severely ill patients suffered swabs Symptom unique Viable Viral RNA virus virus culture were assessed [DOI] 10.3390/jcm10184037 PMC 바로가기 [Article Type] Article
Coronavirus persistence in human respiratory tract and cell culture: An overview인간 호흡기 및 세포 배양에서 코로나바이러스 지속성: 개요Review Published on 2021-09-012022-09-11 Journal: The Brazilian journal of infectious diseases : an [Category] SARS, 유전자 메커니즘, [키워드] case fatality rates Cell Cell culture clinically coronavirus Coronavirus infection Coronavirus infections COVID-19 described Endemic Epidemics Evidence evidence of experimental models Histopathology Host human coronaviruses human respiratory tract Immunocompromised Immunocompromised patients individual Infectious virus Isolation lack Non-productive infection Pathogenesis pathogenic Pathogens persistence Persistence of viral RNA potential mechanism potential mechanisms respiratory pathogen Respiratory pathogens respiratory sample Respiratory samples respiratory tract SARS-CoV-2 SARS-CoV-2 RNA viral pathogenesis Viral RNA [DOI] 10.1016/j.bjid.2021.101632 PMC 바로가기 [Article Type] Review
Monitoring Natural SARS-CoV-2 Infection in Lions ( Panthera leo ) at the Barcelona Zoo: Viral Dynamics and Host Responses바르셀로나 동물원에서 사자 (Panthera Leo)에서 자연 SARS-COV-2 감염 모니터링 : 바이러스 역학 및 숙주 반응Article Published on 2021-08-252022-09-01 Journal: Viruses [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] Panthera leo acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 animals Antigen Barcelona Barcelona Zoo blood sample cats causative agent coronavirus COVID-19 detectable Diagnosis Dynamics Epidemiology events Evidence fecal feces ferrets four lions genomic data hamsters Infection Infectious disease initial Isolation lion monitoring nasal Nasal sample nasal samples natural Neutralizing antibodies neutralizing antibody non-human primates occurred positive Positive test respiratory respiratory sample Respiratory samples respiratory signs response Saliva SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 genome SARS-CoV-2 genome sequence SARS-COV-2 infection SARS-CoV-2 RNA second wave sequence sequences severe acute respiratory syndrome Coronavirus Spain summer Support susceptible tested the SARS-CoV-2 Transmission Viral viral dynamics Viral RNA virus isolation wildlife zoo [DOI] 10.3390/v13091683 PMC 바로가기 [Article Type] Article
Discrepancy between PCR based SARS-CoV-2 tests suggests the need to re-evaluate diagnostic assaysResearch Note Published on 2021-08-172022-10-27 Journal: BMC Research Notes [Category] COVID-19, [키워드] Accuracy amplification conducted COVID-19 COVID19 diagnosis of COVID-19 diagnostic discrepancy eight examined gene target Initially investigated maintain Mild Modification new SARS-CoV-2 objective pathogen Patient PCR PCR assay PCR assays PCR efficiency positive primer binding sites reaction reduced Regular respiratory respiratory sample Result Roche SARS-CoV-2 SARS-CoV-2 test severe COVID-19 spike spike gene strain Strains supplementary material TaqPath tested the patient variant Variation [DOI] 10.1186/s13104-021-05722-5 PMC 바로가기 [Article Type] Research Note
Discrepancy between PCR based SARS-CoV-2 tests suggests the need to re-evaluate diagnostic assaysResearch Note Published on 2021-08-172022-10-27 Journal: BMC Research Notes [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] Accuracy amplification conducted COVID-19 COVID19 diagnosis of COVID-19 diagnostic discrepancy eight examined gene target Initially investigated maintain Mild Modification new SARS-CoV-2 objective pathogen Patient PCR PCR assay PCR assays PCR efficiency positive primer binding sites reaction reduced Regular respiratory respiratory sample Result Roche SARS-CoV-2 SARS-CoV-2 test severe COVID-19 spike spike gene strain Strains supplementary material TaqPath tested the patient variant Variation [DOI] 10.1186/s13104-021-05722-5 PMC 바로가기 [Article Type] Research Note
Discrepancy between PCR based SARS-CoV-2 tests suggests the need to re-evaluate diagnostic assaysPCR 기반 SARS-COV-2 테스트 간의 불일치는 진단 분석을 다시 평가해야합니다.Research Note Published on 2021-08-172022-09-10 Journal: BMC Research Notes [Category] 변종, 치료기술, 치료제, [키워드] Accuracy amplification conducted COVID-19 COVID19 diagnosis of COVID-19 diagnostic discrepancy eight examined gene target Initially investigated maintain Mild Modification new SARS-CoV-2 objective pathogen Patient PCR PCR assay PCR assays PCR efficiency positive primer binding sites reaction reduced Regular respiratory respiratory sample Respiratory samples Result robustness Roche SARS-CoV-2 SARS-CoV-2 test severe COVID-19 spike spike gene strain Strains supplementary material TaqPath tested the patient variant Variation [DOI] 10.1186/s13104-021-05722-5 PMC 바로가기 [Article Type] Research Note
Co-infections observed in SARS-CoV-2 positive patients using a rapid diagnostic test빠른 진단 테스트를 사용하여 SARS-COV-2 양성 환자에서 관찰 된 공동 감염Article Published on 2021-08-112022-09-01 Journal: Scientific Reports [Category] MERS, 진단, 치료기술, 치료제, [키워드] acute respiratory symptoms age Antibiotic resistance Antibiotic therapy Antibiotics antimicrobial resistance average average age Bacteria BAL bioMérieux Bronchoalveolar lavage clinical microbiology Coinfection consecutive patient consecutive patients COVID COVID-19 patients Culture cultures defined detect diagnostic test diagnostic tests evidence of examined female followed by France Genetic H. influenzae hospital information isolate male management marker microbial modulate Molecular medicine MOST obtaining information P. aeruginosa Panel pathogen Pathogens Patient Patient care performed phenomenon Pneumonia pneumoniae positive positive sample potential limitation potential limitations Predictive Rapid Rapid diagnostic test respiratory Respiratory failure respiratory infections respiratory sample Respiratory samples SARS-CoV-2 positive patient sputum targeted therapy Treatment virus viruses [DOI] 10.1038/s41598-021-95772-3 PMC 바로가기 [Article Type] Article
Prolonged detection of complete viral genomes demonstrated by SARS-CoV-2 sequencing of serial respiratory specimens연속 호흡기 시편의 SARS-COV-2 시퀀싱에 의해 입증 된 완전한 바이러스 게놈의 장기 검출Research Article Published on 2021-08-052022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 advanced disease can not clinically Complete confirmed case confirmed cases coronavirus COVID19 patient COVID19 patients demonstrated Diagnosis disease stage early stage gene target Infection initial mapped methodology MONITOR N gene nCoV NGS positive Prevent Prolonged RdRP Real-time PCR reduced required respiratory respiratory sample respiratory specimen SARS-CoV-2 SARS-CoV-2 sequencing sequence Sequencing severe acute respiratory syndrome Coronavirus Spread Stage stages tested the disease the SARS-CoV-2 Transcription triplex Viral viral genome viral sequence viral sequences Viral transmission whole genome [DOI] 10.1371/journal.pone.0255691 PMC 바로가기 [Article Type] Research Article