Human genetic and immunological determinants of critical COVID-19 pneumonia
Review
[키워드] age and gender
age and sex
auto-antibody
autosomal
cellular
childhood
COVID-19
Critical
deficiencies
determinant
explained
FIVE
Genetic
greater
Host
Human
IFNs
IFNα
IFNβ
Immunity
immunological
Inborn error
individual
Infection
men
molecular
Neutralizing
older patients
Patient
plasmacytoid dendritic cells
Pneumonia
proportion
respiratory epithelial cell
respiratory tract
risk of death
SARS-CoV-2
SARS-COV-2 infection
Spread
systemic inflammation
TLR3
TLR7
Trigger
Type I IFN
type I interferon
virus
women
younger patients
[DOI] 10.1038/s41586-022-04447-0 [Article Type] Review
[DOI] 10.1038/s41586-022-04447-0 [Article Type] Review