Forecasting the Effects of the New SARS-CoV-2 Variant in Europe유럽에서 새로운 SARS-CoV-2 변종의 영향 예측Research Article Published on 2021-05-042022-09-10 Journal: The Scientific World Journal [Category] SARS, 변종, [키워드] Analysis Effect Europe Forecasting global analysis New new SARS-CoV-2 pandemic performed SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 variant variant [DOI] 10.1155/2021/5553240 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 has been circulating in northeastern Brazil since February 2020: evidence for antibody detection in asymptomatic patientsSARS-CoV-2는 2020년 2월부터 브라질 북동부에서 순환하고 있습니다: 무증상 환자에서 항체 검출에 대한 증거Comment Published on 2021-05-012022-09-11 Journal: The Journal of Infection [Category] MERS, SARS, 진단, 치료기술, [키워드] antibody Antibody detection asymptomatic patient Brazil circulating collected COVID-19 COVID-19 case Evidence IgG IgM positive reported SAR-CoV-2 SARS-CoV-2 screened tested [DOI] 10.1016/j.jinf.2020.11.037 PMC 바로가기 [Article Type] Comment
A Study of 3CLpros as Promising Targets against SARS-CoV and SARS-CoV-2Article Published on 2021-04-032022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] 3CLpro acute respiratory syndrome addition against SARS-CoV Antiviral Antiviral agents applied approach caused clinical trials Compound compounds coronavirus coronavirus disease COVID-19 COVID-19 patient docking study Drug repurposing FRET in silico indicate information inhibitor inhibitors inhibitory inhibitory activity inhibitory compounds inhibitory effect Interaction Medicine outbreak patients with COVID-19 Proteases Protein residue S1 and S2 SAR-CoV-2 SARS-CoV SARS-CoV-2 SARS-CoV-2 3CL protease selected target Treatment Vaccines variants [DOI] 10.3390/microorganisms9040756 PMC 바로가기 [Article Type] Article
Evaluation of an Automated High-Throughput Liquid-Based RNA Extraction Platform on Pooled Nasopharyngeal or Saliva Specimens for SARS-CoV-2 RT-PCRSARS-CoV-2 RT-PCR에 대한 풀링된 비인두 또는 타액 표본에 대한 자동화된 고처리량 액체 기반 RNA 추출 플랫폼 평가Article Published on 2021-04-022022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] automated comparable COVID-19 COVID-19 pandemic Ct values detect diagnostics Efficiency extraction GAPDH inhibitors Large-scale testing liquid-based nucleic acid extraction magnetic bead Mass screening Nasopharyngeal swab no significant differences nucleic acid nucleic acid extraction Oropharyngeal paucity of data platform pooled specimens positive positive rate real-time RT-PCR RNA RNA extraction RT-PCR Saliva saliva specimen saliva specimens SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 RT-PCR significant difference significant differences specimen specimens the SARS-CoV-2 was performed was used [DOI] 10.3390/v13040615 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Serological testing in frontline health workers in ZimbabweSARS-CoV-2 짐바브웨 최전선 의료 종사자의 혈청 검사Multicenter Study Published on 2021-03-312022-09-10 Journal: PLoS Neglected Tropical Diseases [Category] SARS, 진단, 치료기술, [키워드] addition antibody Antibody testing Asthma Author biosafety biosecurity blood sample city co-morbidity Compliance conducted Contact contact with COVID-19 COVID-19 symptom COVID-19 testing Critical defined determine determined by diabete diabetes diagnostic test effective evaluate exposure to female followed by Health health centres health facilities health system health worker health workers highest highlight hypertension identify indicated Infection Infection prevention Interpretation morbidity Nasopharyngeal swab nasopharyngeal swabs Nurse Nurses occurred participant Participants Patient PCR PCR testing positive predictor Prevalence Prevention and control PROTECT questionnaire Rapid diagnostic test reported SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2 testing Seropositivity Seroprevalence symptoms of COVID-19 tested the SARS-CoV-2 was determined Zimbabwe [DOI] 10.1371/journal.pntd.0009254 PMC 바로가기 [Article Type] Multicenter Study
The bidirectional link between HDL and COVID-19 infectionsCommentary Published on 2021-03-172022-10-29 Journal: Journal of Lipid Research [Category] COVID-19, MERS, [키워드] Apolipoproteins bidirectional COVID-19 COVID-19 infection COVID-19, Coronavirus disease 2019 HDL HDL-C, high-density lipoprotein cholesterol High-density lipoprotein cholesterol Infection LDL-C, low-density lipoprotein cholesterol Low-Density Lipoprotein cholesterol SAR-CoV-2 SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 [DOI] 10.1016/j.jlr.2021.100067 PMC 바로가기 [Article Type] Commentary
Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection심각한 SARS-CoV-2 감염 위험과 혈청 HDL-콜레스테롤 및 아포지단백 A1 수치의 연관성Multicenter Study Published on 2021-03-022022-09-10 Journal: Journal of Lipid Research [Category] 바이오마커, 변종, [키워드] 95% CI, 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age allele alleles ApoA1, apolipoprotein A1 APOE4 apolipoprotein A1 association Biomarker CAD, coronary artery disease cholesterol clinical risk factor Clinical risk factors Coronary artery Coronary artery disease coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19, Coronavirus disease 2019 cumulative cumulative effects diabetes Effect elevated evaluated Evidence feature genetic risk score Genetic variant genetic variants GRS, genetic risk scores HDL-cholesterol higher risk homozygous hypertension ICD-10, International Classification of Diseases, Tenth Revision increase in individual Infection investigated Logistic regression analyses Logistic regression analysis mendelian randomization Mendelian randomization analyses Mendelian randomization analysis metabolic syndrome Mortality MR, Mendelian randomization MVMR, multivariate MR negative controls Novel coronavirus obesity OR, odds ratio outcomes PC, principal component reduced risk respiratory Respiratory disease risk SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 serum serum biomarker serum biomarkers severe acute respiratory syndrome Coronavirus Severe COVID-19 Infection severe respiratory disease severe SARS-CoV-2 severity of COVID-19 Sex susceptible syndrome type 2 diabetes UK biobank were used [DOI] 10.1016/j.jlr.2021.100061 PMC 바로가기 [Article Type] Multicenter Study
Novel RT-ddPCR assays for simultaneous quantification of multiple noncoding and coding regions of SARS-CoV-2 RNAArticle Published on 2021-03-022022-10-04 Journal: Journal of virological methods [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] application arising clinically coding region coding regions complex coronavirus coronavirus transcription Course diagnostic discontinuous transcription Droplet-digital PCR ENhance full length Gene Expression Genome genomic genomic RNA gRNA hallmark Infection novel positive-sense quantification Quantitative Quantitative assays Region RNA SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 RNA semi-quantitative sequence sgRNAs subgenomic mRNA subgenomic RNAs target region Transcription Viral transcription/replication [DOI] 10.1016/j.jviromet.2021.114115 PMC 바로가기 [Article Type] Article
Considerations for stakeholder engagement and COVID-19 related clinical trials’ conduct in sub-Saharan Africa사하라 사막 이남 아프리카에서 이해 관계자 참여 및 COVID-19 관련 임상 시험 수행에 대한 고려 사항Article Published on 2021-03-012022-09-11 Journal: Developing world bioethics [Category] 임상, [키워드] clinical trial clinical trials Community COVID-19 determine facilitate Follow-up formative Government GPP-EP implementation management organizations physical private sector protocol Psychological Research researchers SAR-CoV-2 stakeholder engagement Standard of care sub-Saharan Africa Survivors translation Treatment Trial Vaccine [DOI] 10.1111/dewb.12283 PMC 바로가기 [Article Type] Article
Performance of Saliva Samples for COVID-19 Diagnosis by Using the Allplex TM 2019-nCoV Assay KitMedicine Published on 2021-02-242022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 2019-nCoV ambulatory patient average Cohort collected COVID-19 e genes enrolled invasive lesions less nasal nasopharangeal swabs Nasopharyngeal swab NPs Patient patients performance pharyngeal positive sample representing RT-qPCR RT-qPCR test Saliva Sample SAR-CoV-2 SARS CoV-2 sensitivity Swab target gene Target genes tested viral burden [DOI] 10.3389/fmed.2021.617399 PMC 바로가기 [Article Type] Medicine