Genome-wide analysis of 10664 SARS-CoV-2 genomes to identify virus strains in 73 countries based on single nucleotide polymorphism단일 염기 다형성을 기반으로 73개국의 바이러스 균주를 식별하기 위한 10664 SARS-CoV-2 게놈의 게놈 전체 분석Article Published on 2021-06-012022-09-11 Journal: Virus research [Category] SARS, 변종, 치료법, [키워드] absence addition Analysis applied assessment Care Characteristics Cluster Clustering Clusters code Community Consensus country COVID-19 dataset determine environmental condition Evolution ExoN FIVE function genome-wide analysis Hamming distance Hierarchical hierarchical clustering identify linkage Measures Multiple Multiple sequence alignment mutated Non-synonymous Non-synonymous SNP NSP2 nucleocapsid nucleotide ORF3a performed polymorphism Protein provided Q57H Quantitative reported Research responsible SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 strain SARS-CoV-2 strains sequence Sequence alignment shown Silhouette single nucleotide Single nucleotide polymorphism SNP SNPs stability structures synonymous SNP T85I tendency Vaccine Vaccine design Validity virus virus strain virus strains Visual website [DOI] 10.1016/j.virusres.2021.198401 PMC 바로가기 [Article Type] Article
Mutation in a SARS-CoV-2 Haplotype from Sub-Antarctic Chile Reveals New Insights into the Spike’s DynamicsArticle Published on 2021-05-112022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] 501Y.V1 501Y.V2 accompanied B.1.1.28.1 B.1.1.7 B.1.351 Comparative continuous surveillance COVID19 D614G domain Dynamics Haplotype higher infectivity highest incidence rate indicated insight Lineage lineages molecular molecular analysis molecular mechanism mutant Mutation New nine Occurrence P.1 Receptor binding domain Region replaced resulting SARS-CoV-2 SARS-CoV-2 strains SARS-CoV-2 variants SARS-CoV2 significant increase Spike protein strain synergistic variant Variation virulence [DOI] 10.3390/v13050883 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Spike Protein Stabilized in the Closed State Induces Potent Neutralizing ResponsesVaccines and Antiviral Agents Published on 2021-05-072022-10-30 Journal: Journal of Virology [Category] COVID-19, SARS, [키워드] ACE2 antibody B.1.351 binding conformational conformations described epitope expected Glycoproteins immune response Immunity immunization immunized include individuals induce inhibit Interaction long-lasting majority mRNA vaccine Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody response neutralizing response observation P.1 potent prefusion Prevent Protein raised RBD receptor Receptor binding domain receptor binding site recruit response robust S protein SARS-CoV-2 SARS-CoV-2 strains SARS-CoV-2 vaccine SARS-CoV-2 variants sequence sera spike Spike protein spikes stability state T cell response the antibody response the RBD the spike protein trimer trimeric S protein Vaccination strategy Vaccine Vaccines variants variants of concern viral spike protein virion [DOI] 10.1128/JVI.00203-21 PMC 바로가기 [Article Type] Vaccines and Antiviral Agents
Genetic Evidence and Host Immune Response in Persons Reinfected with SARS-CoV-2, Brazil브라질, SARS-CoV-2에 재감염된 사람의 유전적 증거 및 숙주 면역 반응Research Published on 2021-05-012022-09-10 Journal: Emerging Infectious Diseases [Category] MERS, SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Brazil Clinical symptoms Cluster coronavirus coronavirus disease COVID-19 detectable first episode healthy Humoral immunity Humoral response Hypothesis innate response manifested Mild Neutralizing Next-generation sequencing Patient Person Reinfection respiratory respiratory infections response SARS-CoV-2 SARS-CoV-2 replication SARS-CoV-2 strains severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Viral viral loads viruses zoonoses [DOI] 10.3201/eid2705.204912 PMC 바로가기 [Article Type] Research
A Novel Immunofluorescence Assay for the Rapid Serological Detection of SARS-CoV-2 InfectionSARS-CoV-2 감염의 신속한 혈청학적 검출을 위한 새로운 면역형광 분석법Article Published on 2021-04-242022-09-01 Journal: Viruses [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] antibody Antiviral treatment assessment assessments Biomarker blood sample Blood samples capture Cell collected confirmation country COVID-19 COVID-19 pandemic cross-reactivity dependent on detect detection exogenously Express expressing fluorescent Health Height IgG antibodies IgG antibody immunofluorescence assay individual infancy Infection novel Oxford pandemic Patient patient sera positive individual positive individuals predict Protein Rapid SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strains SARS-CoV-2 variants serology serum subsequent Transmission vaccination variants [DOI] 10.3390/v13050747 PMC 바로가기 [Article Type] Article
A small interfering RNA (siRNA) database for SARS-CoV-2Article Published on 2021-04-232022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 치료제, [키워드] Antiviral approaches binding characterized contributing to Coronavirus disease 2019 COVID-19 COVID-19 pandemic Data integration database databases dataset effective response evaluated faster Features global pandemic help Human genome information Laboratory Metadata nucleotide provided RNA RNA genome SARS-CoV-2 SARS-CoV-2 strains sequence siRNA table target target gene the SARS-CoV-2 thermodynamic [DOI] 10.1038/s41598-021-88310-8 PMC 바로가기 [Article Type] Article
Genomic Surveillance of Circulating SARS-CoV-2 in South East Italy: A One-Year Retrospective Genetic Study이탈리아 남동부에서 순환하는 SARS-CoV-2의 게놈 감시: 1년 후향적 유전 연구Article Published on 2021-04-222022-09-10 Journal: Viruses [Category] MERS, SARS, 변종, [키워드] Apulia Basilicata circulating viral variants clade collected COVID-19 COVID-19 pandemic draft East epidemiological epidemiological surveillance Genetic Genome Genome sequencing Genomic analysis Genomic surveillance Infection Italy Lineage lineages new SARS-CoV-2 Nextstrain clade Pangolin lineage performed regions SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 strains SARS-CoV-2 variant SARS-CoV-2 variants second wave sequenced South Spread Surveillance Therapies transmission rate Vaccine variants of concern Viral viral dynamics Whole genome sequencing [DOI] 10.3390/v13050731 PMC 바로가기 [Article Type] Article
Pervasive transmission of E484K and emergence of VUI-NP13L with evidence of SARS-CoV-2 co-infection events by two different lineages in Rio Grande do Sul, Brazil브라질 리오그란데두술에서 2개의 다른 계통에 의한 SARS-CoV-2 동시 감염 사건의 증거와 함께 E484K의 만연한 전파 및 VUI-NP13L의 출현Article Published on 2021-04-152022-09-11 Journal: Virus research [Category] SARS, 변종, [키워드] B.1.1.28 Brazil caused characterized circulating Cluster Clustering analysis Co-infection COVID-19 E484K effective emergence event Evidence genomic Genomic surveillance identify independent investigated Lineage lineages media MOST Mutation mutations novel vaccines Occurrence other variant other variants P13L. raised recent Rio Grande SARS-CoV-2 SARS-CoV-2 lineage SARS-CoV-2 strains Scientific community sequenced Social distancing measure social distancing measures South Africa Spread Strains Transmission transmission rate United Kingdom Vaccines variant widespread [DOI] 10.1016/j.virusres.2021.198345 PMC 바로가기 [Article Type] Article
Genomic Analysis and Lineage Identification of SARS-CoV-2 Strains in Migrants Accessing Europe Through the Libyan Route리비아 경로를 통해 유럽에 접근하는 이민자의 SARS-CoV-2 균주의 게놈 분석 및 계통 식별Public Health Published on 2021-04-152022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 African asylum-seeker B.1 lineage conducted coronavirus Europe genetic variability Genetic variation genomes identification IMPROVE investigated knowledge Libya Lineage Local majority Mediterranean Sea migrant molecular molecular surveillance NGS Phylogenetic pilot study polymorphism positive Region representing rescued respiratory route SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 strains SARS-CoV-2 transmission sequence sequences Sequencing severe acute respiratory syndrome Coronavirus Sicily strain Surveillance sustained tested Transmission Transport Travel variants vessel Viral viral genome whole genome sequence [DOI] 10.3389/fpubh.2021.632645 PMC 바로가기 [Article Type] Public Health
OverCOVID: an integrative web portal for SARS-CoV-2 bioinformatics resourcesOverCOVID: SARS-CoV-2 생물정보학 리소스를 위한 통합 웹 포털Article Published on 2021-03-192022-09-10 Journal: Journal of Integrative Bioinformatics [Category] SARS, 유전자 메커니즘, [키워드] accelerate addition available data bioinformatics bioinformatics resources Biology biology of SARS-CoV-2 caused Clinical data Clinical research coronavirus COVID-19 database databases facilitate Frame genomic Health help information Interaction Novel coronavirus novel coronavirus SARS-CoV-2 Other portal produced proteomic provided Research researcher resource SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 strains scientist [DOI] 10.1515/jib-2020-0046 PMC 바로가기 [Article Type] Article