SARS-CoV-2 viral – Page 7 – Communicable Diseases Research

Identification of cytotoxic T cells and their T cell receptor sequences targeting COVID-19 using MHC class I-binding peptides

MHC 클래스 I 결합 펩타이드를 사용하여 COVID-19를 표적으로 하는 세포독성 T 세포 및 T 세포 수용체 서열 확인

Article

Published on 2022-02-022022-09-10
Journal: Journal of Human Genetics [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 치료기술, 치료제,

The Impact of COVID-19 on Liver Injury

Review article

Published on 2022-02-012022-10-05
Journal: The American journal of the medical sciences [Category] COVID19(2023년), SARS, 바이오마커, 치료제,

The possible role of ursolic acid in Covid-19: A real game changer

Research article

Published on 2022-02-012022-10-05
Journal: Clinical nutrition ESPEN [Category] COVID19(2023년), SARS, 신약개발, 임상, 치료제,

Viral Culture Confirmed SARS-CoV-2 Subgenomic RNA Value as a Good Surrogate Marker of Infectivity

바이러스 배양은 SARS-CoV-2 서브게놈 RNA 값을 감염성의 좋은 대리 표지자로 확인했습니다.

Article

Published on 2022-01-192022-09-11
Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 바이오마커, 유전자 메커니즘, 치료기술,

Development and utilization of a surrogate SARS-CoV-2 viral neutralization assay to assess mRNA vaccine responses

mRNA 백신 반응을 평가하기 위한 대리 SARS-CoV-2 바이러스 중화 분석의 개발 및 활용

Research Article

Published on 2022-01-182022-09-12
Journal: PLoS ONE [Category] 진단,

[키워드] angiotensin angiotensin converting enzyme biosafety biotinylated booster Booster vaccine Complete configuration correlation COVID COVID-19 COVID-19 patient COVID-19 patients Decline declines development doses ELISA ELISAs enzyme evaluate gold gold standard help heterogeneous highlight Highlights host receptor immunoassay Infection inhibitory activity Interaction Longitudinal analyses longitudinal analysis mRNA vaccine Neutralization assay neutralization test Neutralizing activity plaque reduction neutralization Plaque reduction neutralization test post vaccination PRNT raise RBD receptor Receptor binding domain recipient Recovered COVID-19 patients response SARS-CoV-2 immunity SARS-CoV-2 spike SARS-CoV-2 viral serum Serum neutralizing antibody significant difference significant differences significantly higher Spike protein Test tested vaccinated individual vaccination Vaccine vaccine response vaccine responses viral culture was used within 6 months
[DOI] 10.1371/journal.pone.0262657 PMC 바로가기 [Article Type] Research Article

Postmortem high-dimensional immune profiling of severe COVID-19 patients reveals distinct patterns of immunosuppression and immunoactivation

심각한 COVID-19 환자의 사후 고차원 면역 프로파일링은 면역 억제 및 면역 활성화의 독특한 패턴을 나타냅니다

Article

Published on 2022-01-122022-09-10
Journal: Nature Communications [Category] 바이오마커, 치료기술, 치료법,

[키워드] activated Activation Analysis antigens approach Autopsy Cell cell type cell types cells Complete coronavirus disease Coronavirus disease 2019 correlation correlations COVID-19 COVID-19 disease Deceased dendritic cell diagnostic distal etiology function Gene regulation in immune cells hallmark histological Imaging the immune system immune profiling immune response immune responses Immunosuppression induce information lymphocyte Lymphocytes men multiple organs myeloid cell myeloid cells Pathogenesis PD-1 Postmortem prevalent progression proximal reveal SARS-COV-2 infection SARS-CoV-2 viral SARS-CoV-2 viral infection severe COVID-19 severe COVID-19 disease severe COVID-19 patient Systems analysis therapy these cell These cells transcriptional transcriptomic Viral Viral antigen viral antigens viral infection Viral load Wuhan Wuhan, China
[DOI] 10.1038/s41467-021-27723-5 PMC 바로가기 [Article Type] Article

Trajectory of Viral RNA Load Among Persons With Incident SARS-CoV-2 G614 Infection (Wuhan Strain) in Association With COVID-19 Symptom Onset and Severity

COVID-19 증상 발병 및 중증도와 관련하여 SARS-CoV-2 G614 감염(우한 균주)이 발생한 사람의 바이러스 RNA 부하 궤적

Randomized Controlled Trial

Published on 2022-01-102022-09-10
Journal: JAMA Network Open [Category] 변종, 임상, 진단, 치료기술,

[키워드] association Asymptomatic baseline Characteristics characterized clinical trial Clinical trial design clinical trials Cohort cohort study collected conducted correlated COVID-19 COVID-19 symptom Ct value cycle threshold Cycle threshold value Data analysis enrolled exposure finding Follow-up followed by G614 variant Importance incident individual Infection infections initial laboratory-confirmed SARS-CoV-2 infection linear load measure median median age men Mild symptom mild symptoms mixed-effects model moderate molecular natural history objective occurred Onset pandemic participant peak Person Point positive positive swab prospective cohort study public health referred to Relevance Result RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA detection SARS-CoV-2 viral SARS-CoV-2 viral load SARS-CoV-2 viral RNA SARS-CoV-2–positive sequenced sample setting severe symptom severity shedding Spread statistical model strain Swab swab sample swab samples Symptom symptom onset symptom severity symptomatic tested the patient the SARS-CoV-2 therapeutic These data trajectory Viral viral lineage Viral load Viral RNA viral shedding viral variant virus were used with COVID-19 women Wuhan Wuhan strain
[DOI] 10.1001/jamanetworkopen.2021.42796 PMC 바로가기 [Article Type] Randomized Controlled Trial

Neutralization breadth of SARS-CoV-2 viral variants following primary series and booster SARS-CoV-2 vaccines in patients with cancer

암 환자에서 1차 시리즈 및 부스터 SARS-CoV-2 백신에 따른 SARS-CoV-2 바이러스 변이체의 중화 폭

Comparative Study

Published on 2022-01-102022-09-11
Journal: Cancer cell [Category] 변종, 진단,

Influence of Fasting Plasma Glucose Level on Admission of COVID-19 Patients: A Retrospective Study

Research Article

Published on 2022-01-062022-10-29
Journal: Journal of Diabetes Research [Category] COVID-19,

[키워드] acute respiratory syndrome Admission age analyzed Beijing Biomarkers blood glucose CD8 change Chest CT Clinical data collected coronavirus coronavirus disease correlated COVID-19 COVID-19 patient COVID-19 patients diabetes elevated evaluated fasting Gender Glucose hazard ratio Health independent inflammatory reaction influence Intensive Laboratory Level logistic regression model Mortality objective outcome outcomes plasma positive previous study Prolonged recruited Research Result Retrospective study risk factor RNA SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 viral severe disease course significantly Spread T cell viral shedding
[DOI] 10.1155/2022/7424748 PMC 바로가기 [Article Type] Research Article

SARS Antibody Testing in Children: Development of Oral Fluid Assays for IgG Measurements

소아에서 SARS 항체 검사: IgG 측정을 위한 구강액 분석법 개발

Research Article

Published on 2022-01-052022-09-10
Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제,

[키워드] 95% CI 95% confidence interval Adults antibody antibody kinetics barrier best Blood capture children collected COVID-19 development enzyme immunoassay enzyme immunoassays exposure to healthy children IgG Infection Laboratory less measurement MONITOR oral oral fluid pandemic pediatric populations primary endpoint Protein RBD RBD antigen reducing Saliva SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 surveillance SARS-CoV-2 viral School Schools sensitivity Sensitivity and specificity serum serum antibodies specificity Spike protein Spread Surveillance surveys target population Testing transudate United Kingdom venipuncture Viral were assessed
[DOI] 10.1128/spectrum.00786-21 PMC 바로가기 [Article Type] Research Article