High Seroprevalence of SARS-CoV-2 in White-Tailed Deer (Odocoileus virginianus) at One of Three Captive Cervid Facilities in Texas텍사스에 있는 세 곳의 자궁경부 사육 시설 중 하나에서 흰꼬리사슴(Odocoileus virginianus)에서 SARS-CoV-2의 높은 혈청유병률Article Published on 2022-04-272022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] axis can not captive cervid Contact coronavirus Coverage Critical cross-sectional cross-sectional study deer endpoint titer endpoint titers epizootiology Evidence evidence of explained facilitate facilitated facility Free Health horizontal transmission Human human population Impact increasingly Infection Neutralization assay Neutralizing antibodies neutralizing antibody Odocoileus population increase PRNT Region reported reservoir SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 vaccine seronegative seropositive Seroprevalence spillover subset Support Swab tested the United State The United States These data Transmission transmission of SARS-CoV-2 United States variants variants of concern virus white-tailed deer zoonosis [DOI] 10.1128/spectrum.00576-22 PMC 바로가기 [Article Type] Article
Immune Response to Third Dose BNT162b2 COVID-19 Vaccine Among Kidney Transplant Recipients-A Prospective Study신장 이식 환자의 3차 접종 BNT162b2 COVID-19 백신에 대한 면역 반응-전향적 연구Article Published on 2022-04-212022-09-12 Journal: Transplant International [Category] COVID19(2023년), SARS, 진단, [키워드] 95% confidence interval anti-spike antibody antibody Antibody Response BNT162b2 cellular cellular response conducted control group controls COVID-19 COVID-19 vaccine Cutoff demonstrated dose evaluate evaluated healthcare humoral identify immune response Immunosuppression immunosuppression reduction kidney transplant recipient kidney transplant recipients kidney transplant recipients. log mRNA vaccine Multivariate analysis Odds ratio Participants Primary outcome Prospective Prospective Study reduction remained response Result SARS-CoV-2 second dose seronegative subset T-cell Response Transplant vaccination Vaccine vaccine dose variable [DOI] 10.3389/ti.2022.10204 PMC 바로가기 [Article Type] Article
An Observational Cohort Study on the Incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and B.1.1.7 Variant Infection in Healthcare Workers by Antibody and Vaccination Status중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2) 감염 및 B.1.1.7 항체 및 백신 접종 상태에 따른 의료 종사자의 변이 감염 발생률에 대한 관찰 코호트 연구Observational Study Published on 2022-04-092022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), SARS, 변종, 임상, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted age anti-spike antibodies anti-spike antibody antibody B.1.1.7 B.1.1.7 variant BNT162b2 ChAdOx1 ChAdOx1 nCoV-19 Chain Reaction changes in confidence interval coronavirus coronavirus 2 detectable dose doses evade Evidence evidence of HCW HCWs healthcare healthcare worker Healthcare workers Immunity incidence incidence rate Infection investigated longitudinal cohort study natural natural immunity natural infection no evidence of Oxford-AstraZeneca pandemic PCR-positive Pfizer-BioNTech Poisson regression polymerase chain polymerase chain reaction provided rate ratio reduced respiratory resulting robust S-gene SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants Sequencing seronegative seropositive Seropositivity severe acute respiratory syndrome Coronavirus Sex Single-dose status symptomatic symptomatic and asymptomatic symptomatic infection United Kingdom vaccination Vaccine vaccine dose Vaccine-induced immunity whole genome Whole genome sequencing without symptom worker [DOI] 10.1093/cid/ciab608 PMC 바로가기 [Article Type] Observational Study
Passive transfer of SARS-CoV-2 antibodies with platelet transfusions혈소판 수혈을 통한 SARS-CoV-2 항체의 수동 전달Article Published on 2022-04-012022-09-11 Journal: Transfusion [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] antibodies antibody Antibody titer apheresis Blood clinician conducted COVID-19 demonstrated DiaSorin Effect eligible evaluated IgG IgG antibody median New York occur passive transfer Patient Platelet platelet transfusion Platelets Primary outcome Quality assurance recipient recipients Retrospective analysis S1/S2 SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 spike protein seronegative significantly higher Spike protein study inclusion the median The United States transfer transferred transfusion United States Volume [DOI] 10.1111/trf.16841 PMC 바로가기 [Article Type] Article
ACE2 Serum Levels as Predictor of Infectability and Outcome in COVID-19COVID-19의 감염 가능성 및 결과 예측자로서의 ACE2 혈청 수준Article Published on 2022-03-232022-09-12 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, [키워드] ACE2 analysed Angiotensin II antibodies antibody Antibody Response Biomarker cellular Cohort COVID-19 COVID-19 disease determinant generate Health care worker high risk IgG antibody infected patient Infection lentivirus Level negative control neutralization neutralize Patient predict PROTECT pseudotyped respiratory symptom risk SARS-COV-2 infection sera seronegative seropositive serum Serum level severity significantly higher soluble ACE2 subject subjects Subtypes Symptoms tested uninfected virus [DOI] 10.3389/fimmu.2022.836516 PMC 바로가기 [Article Type] Article
Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)코로나19 이후 증후군 및 만성 피로 증후군(ME/CFS) 환자의 내피 기능 장애 및 변경된 내피 바이오마커Article Published on 2022-03-222022-09-11 Journal: Journal of Translational Medicine [Category] MERS, SARS, 바이오마커, [키워드] ACE ACE2 age analysed angiopoietin angiotensin Angiotensin-converting enzyme association Biomarker Biomarkers blood pressure BMI chronic fatigue syndrome clinical parameter Clinical parameters cohort of patient Concentration criteria defined Diagnostic Criteria dysfunction elevated Encephalomyelitis endocan endothelial endothelial cells Endothelial dysfunction endothelial function Endotheliitis Endothelin Endothelin-1 Endothelium ET-1 Evidence exhibited fatigue fatigue syndrome FIVE HCs healthy control hyperaemia IL-8 infect investigated malaise Myalgic encephalomyelitis/chronic fatigue syndrome paradoxical Pathomechanism Patient patients peripheral positive correlation post-COVID syndrome profile reactive Reactive hyperaemia index. SARS-CoV-2 seronegative serum Sex shown significantly subgroups subset Symptom syndrome [DOI] 10.1186/s12967-022-03346-2 PMC 바로가기 [Article Type] Article
SARS-CoV-2 T Cell Response in Severe and Fatal COVID-19 in Primary Antibody Deficiency Patients Without Specific Humoral Immunity특정 체액 면역이 없는 1차 항체 결핍 환자의 중증 및 치명적인 COVID-19에서 SARS-CoV-2 T 세포 반응Article Published on 2022-03-102022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] activated acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration Analysis analyzed antibody autoantibodies autoantibody Blood CD169 CD4 cellular characterized clearance clinical disease Comorbidities Comorbidity convalescent convalescent plasma Convalescent plasma (CP) coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 cytokine deficiency detectable elevated examined excluded expression fatal COVID-19 flow cytometry healthy individuals heterogeneous humoral humoral immune response IgG Immunity immunodeficiency immunological immunological mechanism Inborn errors indicate innate immune response Innate immunity interferon interferons lack marker median monoclonal antibody Monocytes morbidity Mortality mucosal naïve nucleocapsid outcome Patient patients peptide peptide pool Peripheral blood persistence phenotype primary antibody primary antibody deficiency (PAD) Primary immunodeficiencies primary immunodeficiencies (PID) producing Prophylactic respiratory response Risk factors robust SARS-CoV-2 SARS-CoV-2 immunity SARS-CoV-2 RNA SARS-CoV-2 spike SARS-CoV-2 viral shedding seronegative severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Severe case severe cases severe COVID-19 patient SIGLEC1 Specific T cell T cell response T cells Treatment type I interferon type I interferon response type I interferons undetectable Viral viral clearance viral shedding with COVID-19 [DOI] 10.3389/fimmu.2022.840126 PMC 바로가기 [Article Type] Article
Detection of anti-Histoplasma capsulatum antibodies and seroconversion patterns in critically ill patients with COVID-19: An underdiagnosed fungal entity complicating COVID-19?COVID-19에 감염된 중환자에서 항히스토플라스마 캡슐화 항체 및 혈청전환 패턴의 검출: COVID-19를 복잡하게 만드는 과소 진단된 곰팡이 개체?Article Published on 2022-03-042022-09-11 Journal: Medical mycology [Category] MERS, SARS, 진단, 치료기술, [키워드] AIDS analyzed antibody Antibody titer Antibody titers Awareness baseline Bearing Buenos Aire Buenos Aires candidiasis classical clinician Co-infection COVID-19 pneumonia COVID-19-associated mycoses Critically ill Critically ill patient critically ill patients death detection Diagnosis died Endemic endemic area endemicity evaluated FIVE fungal fungal disease fungal infections fungus help Histoplasma Histoplasma capsulatum Histoplasmosis HIV/AIDS Hospitalized house ICU IgG antibodies IgG antibody in-house ELISA increased risk infections invasive Invasive pulmonary aspergillosis mind morbidity morbidity and mortality Mycoses Patient positive Prevent pulmonary aspergillosis reduce respiratory Respiratory failure Respiratory function risk risk factor SARS-CoV-2 Sepsis sera Seroconversion seronegative seropositive serum sample serum samples severe COVID-19 Severe COVID-19 pneumonia severe respiratory failure specific IgG antibodies Treatment with COVID-19 worsening [DOI] 10.1093/mmy/myac012 PMC 바로가기 [Article Type] Article
Risk of Reinfection After Seroconversion to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): A Population-based Propensity-score Matched Cohort Study중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)로의 혈청전환 후 재감염 위험: 인구 기반 성향 점수 일치 코호트 연구Article Published on 2022-03-012022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus age antibody BMI body mass body mass index Clinical practice conducted controls coronavirus coronavirus 2 COVID-19 Effectiveness Follow-up follow-up period Gender hazard health authorities Health authority help immune response immunodeficiency incidence individual Infection infection rate Matched pandemic participant Participants positive Primary outcome priority protection reduction in Reinfection respiratory retrospective SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 test selected Seroconversion serological serological assays seronegative seropositive individual seropositive individuals seropositive participants seropositive subject seropositive subjects seroprevalence survey Serosurvey smoking status Standard deviation Switzerland Vaccine [DOI] 10.1093/cid/ciab495 PMC 바로가기 [Article Type] Article
Lack of association between pandemic chilblains and SARS-CoV-2 infection유행성 아동과 SARS-CoV-2 감염 사이의 연관성 부족420 Published on 2022-02-252022-09-12 Journal: Proceedings of the National Academy of Sciences of [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis antibodies antibody Antibody Response Antibody responses antiviral immune response assays association biopsy causative agent chilblain chilblains Cohort Connecticut coronavirus covid toe diagnose diagnosed Direct Endpoint enrolled enzyme-linked immunosorbent enzyme-linked immunosorbent assay epitope Evidence evidence of First wave immune profiling immunohistochemical staining incidence infections interferon Microarray molecular Most patients pandemic Patient PCR peptide performed pernio positive robust SARS-CoV-2 SARS-COV-2 infection Sequencing seronegative serum severe acute respiratory syndrome Coronavirus Significance staining subsequent Support T cell T cell receptor T cell response T cell responses tissue tissues viral infection were assessed [DOI] 10.1073/pnas.2122090119 PMC 바로가기 [Article Type] 420