Elevated levels of serum CDCP1 in individuals recovering from severe COVID-19 disease심한 covid-19 질병으로부터 회복되는 개인에서 혈청 cdcp1의 높은 수준Research Paper Published on 2022-02-282022-09-10 Journal: Aging (Albany NY) [Category] MERS, 바이오마커, [키워드] Biomarker Biomarkers carbon monoxide CDCP1 correlation correlations COVID-19 difference diffusing diffusing capacity discharge group hospital hospital discharge Hospitalization identify implication independent predictors Indicator individual Inflammatory biomarker inflammatory biomarkers laboratory-confirmed Laboratory-confirmed COVID-19 Level lung abnormalities lung abnormality Lung function median onset of symptom Patient predictor prognostic recovery recruited SARS-CoV-2-infected patient SARS-CoV-2-infected patients serum Severe case severe cases severe COVID-19 disease severe disease severity severity of COVID-19 significant difference significantly lower Spain sputum Sputum sample sputum samples survivor Symptom were measured [DOI] 10.18632/aging.203898 PMC 바로가기 [Article Type] Research Paper
The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication2019년 코로나바이러스 질환의 폐외 합병증의 기저 메커니즘 및 치료적 의미Review Published on 2022-02-232022-09-10 Journal: Signal Transduction and Targeted Therapy [Category] COVID19(2023년), MERS, SARS, 바이오마커, 변종, 임상, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect caused clinical implication clinical implications Complication complications complications of COVID-19 coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 disease Disease progression Effect feature global public health host inflammatory response immunological indirect mechanism Infectious diseases management mechanism multifactorial Pathogenesis pathophysiologic patients with COVID-19 Perspective potential therapeutic target potential therapeutic targets provide Recognition respiratory respiratory distress Respiratory system Respiratory tract diseases SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe cases severe pneumonia syndrome therapeutic Therapeutic strategies [DOI] 10.1038/s41392-022-00907-1 PMC 바로가기 [Article Type] Review
Long-term follow-up of dynamic brain changes in patients recovered from COVID-19 without neurological manifestations신경계 증상 없이 COVID-19에서 회복된 환자의 역동적인 뇌 변화에 대한 장기 추적 관찰Clinical Medicine Published on 2022-02-222022-09-12 Journal: JCI Insight [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] abnormality acute phase baseline Brain cerebral blood flow change changes in China complete recovery consequence cortical COVID-19 COVID-19 cases cross-sectional discharge discharged discharged patient dynamic Effect Evidence Follow-up foundation Gray matter group Guidance hospital hypoperfusion initial investigated magnetic resonance imaging mild cases morphology natural Neuroimaging neurological neurological manifestation neurological manifestations neuroscience nuclei numbers of patient Patient provide reduced returned Science Severe case severe cases subject Volume White matter [DOI] 10.1172/jci.insight.155827 PMC 바로가기 [Article Type] Clinical Medicine
A Review of the Role of Imaging Modalities in the Evaluation of Viral Myocarditis with a Special Focus on COVID-19-Related MyocarditisReview Published on 2022-02-212022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] acute respiratory syndrome cardiac cardiac CT Cardiac imaging cardiac magnetic resonance imaging (CMR) coronavirus coronavirus disease COVID-19 COVID-19-related myocarditis death Diagnosis disease echocardiography Endomyocardial biopsy fatigue focus gold standard heterogeneous imaging Inflammation invasive malaise modality myocardial involvement myocarditis Myocardium noninvasive nonspecific pandemic PET-CT review role sensitivity severe cases Shock SPECT Symptom viral infection viral myocarditis [DOI] 10.3390/diagnostics12020549 PMC 바로가기 [Article Type] Review
A Lateral Flow Immunoassay Coupled with a Spectrum-Based Reader for SARS-CoV-2 Neutralizing Antibody DetectionArticle Published on 2022-02-102022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Accuracy acute respiratory syndrome addition approach approaches AstraZeneca caused collected coronavirus coronavirus disease Coronavirus disease 2019 (COVID-19) COVID-19 antibody COVID-19-related death demonstrated detect detection detection rate diagnoses diagnosing Diagnosis diagnostic effective enzyme-linked immunosorbent exhibited feasible Flow high correlation High-resolution Infection Lateral lateral flow immunoassay limitation mild case Negative predictive value neutralizing antibody Patient patients plasma sample polymerase chain Positive predictive value protocols ROC Curve SARS-CoV-2 SARS-COV-2 infection sensitivity Serological assay serum sample Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) severe cases shown specificity Stage tested the disease [DOI] 10.3390/vaccines10020271 PMC 바로가기 [Article Type] Article
In Patients with Severe COVID-19, the Profound Decrease in the Peripheral Blood T-Cell Subsets Is Correlated with an Increase of QuantiFERON-TB Gold Plus Indeterminate Rates and Reflecting a Reduced Interferon-Gamma ProductionArticle Published on 2022-02-072022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] Analysis CD3 CD3+ CD4/CD8 CD4+ CD8+ Characteristics COVID-19 COVID-19 patients demonstrated gold GraphPad Prism hospitalized COVID-19 patient hospitalized COVID-19 patients IFN IFN-γ IGRA increase Increased independent predictor indeterminate lymphopenia median multivariable analysis non-survivor Non-survivors oxygen supply Patient patients patients hospitalized peripheral Peripheral blood positive correlation Prevalence Production QuantiFERON-TB Gold Rate Reflecting required Retrospective study SARS-CoV-2 severe cases severe COVID-19 patient stratified survivor T-cell T-lymphocyte to define was performed [DOI] 10.3390/life12020244 PMC 바로가기 [Article Type] Article
Coagulation Disorders and Thrombosis in COVID-19 Patients and a Possible Mechanism Involving Endothelial Cells: A ReviewReview Published on 2022-02-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] addition adhesion molecules Adults affected angiotensin-converting enzyme 2 antibody Blood Cell cell activation changes in characterized circulation Coagulation coagulation disorder Coagulopathy contribute Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients Critical case D-dimer death disease disorder dysfunction elevated endothelial cells Endothelium Evidence Express higher risk increased risk Inflammation Involving laboratory abnormalities mechanism Mortality nitric oxide Older organ dysfunction outcome pandemic pathophysiological Platelet predict proinflammatory mediator Prothrombin time released Research review SARS-CoV-2 severe cases subendothelial thrombosis tissue upregulation virus [DOI] 10.14336/AD.2021.0704 PMC 바로가기 [Article Type] Review
Hypersensitivity may be involved in severe COVID-19과민증은 심각한 COVID-19에 관련될 수 있습니다Article Published on 2022-02-012022-09-11 Journal: Clinical and experimental allergy : journal of the [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] activated AhR airway analysed anti-SARS-CoV-2 Anti-SARS-CoV-2 specific IgE antibodies cell activation Clinical severity conducted coronavirus disease Coronavirus disease 2019 correlated Corticosteroid Corticosteroids COVID-19 detect Early convalescence endoscopy Evidence evidence of histological hypersensitivity hypersensitivity reactions hypoxemic Hypoxemic respiratory failure IgE IgE-mediated hypersensitivity reactions inflammatory storm intestinal tissues involved lung mast cell Mast cells mechanism Methylprednisolone Methylprednisolone therapy nucleocapsid nucleocapsid protein PaO Pathogenesis positive Protein provocation test pulmonary Pulmonary function test pulse pulse methylprednisolone therapy Respiratory failure S1 protein serum Serum level severe cases severe COVID-19 Severity Score significantly higher [DOI] 10.1111/cea.14023 PMC 바로가기 [Article Type] Article
Respiratory and peripheral muscular ultrasound characteristics in ICU COVID 19 ARDS patientsICU COVID 19 ARDS 환자의 호흡기 및 말초 근육 초음파 특성Observational Study Published on 2022-02-012022-09-11 Journal: Journal of critical care [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] Admission affected ARDS ARDS patient benefit change Characteristics clinically coronavirus disease Coronavirus disease 2019 correlation COVID 19 COVID19 cross-sectional area cumulative dead patients develop Diaphragm diaphragmatic echogenicity Fluid balance Grayscale Grayscale analysis ICU intubated patient material mechanical ventilation muscle muscles muscular Muscular ultrasound. observational study parasternal Patient performed prospective observational study Protein reduce respiratory severe cases significantly significantly lower survived therapy thickness Ultrasound Urine [DOI] 10.1016/j.jcrc.2021.09.007 PMC 바로가기 [Article Type] Observational Study
COVID-19 vaccine is correlated with favourable epidemiological indicators in the Auvergne-Rhône-Alpes region (France): An ecological studyCOVID-19 백신은 Auvergne-Rhône-Alpes 지역(프랑스)에서 유리한 역학 지표와 상관관계가 있습니다: 생태학적 연구Article Published on 2022-01-312022-09-11 Journal: Vaccine [Category] SARS, 변종, [키워드] causal relationship Complete correlated Coverage COVID-19 COVID-19 vaccine ecological Ecological study effective Effectiveness Epidemic epidemiological epidemiological data evaluate France French Hospital admissions hospitalisation implementation Infection measure MONITOR Open data reducing reduction reported Reproduction number SARS-CoV-2 severe cases Support the vaccine Transmissibility vaccination Vaccine Vaccine impact variants of concern Viral load [DOI] 10.1016/j.vaccine.2021.12.036 PMC 바로가기 [Article Type] Article