Emerging potential mechanisms and predispositions to the neurological manifestations of COVID-19COVID-19의 신경학적 징후에 대한 잠재적인 메커니즘 및 소인의 출현Review Published on 2021-09-152022-09-11 Journal: Journal of the neurological sciences [Category] SARS, 유전자 메커니즘, [키워드] autonomic cellular Cognition COVID COVID-19 Cytokine storm demographic factor downstream Effect effective Factors Genetic healthcare services imperative increasingly individual management manifestation mechanism Mental molecular NeuroCOVID neurological Neurological disease neurological manifestation NEUROLOGY phenotype potential mechanism predisposition Prevent reported SARS-CoV-2 significantly Spectrum Surveillance Treatment virus with COVID-19 [DOI] 10.1016/j.jns.2021.117608 PMC 바로가기 [Article Type] Review
Pachychoroid Spectrum Disorder Findings in Patients with Coronavirus Disease 2019Case Series Published on 2021-09-132022-10-31 Journal: Case Reports in Ophthalmological Medicine [Category] COVID-19, [키워드] association autofluorescence Bilateral Complete coronavirus disease Corticosteroid COVID-19 COVID-19 recovered patient disorder emotional Eplerenone exacerbated finding Fluorescein Inflammation Occurrence ocular Optical coherence tomography Patient pigment epitheliopathy reported resolved Result Retinal detachment Spectrum Stress the patient therapy Treatment vessel with COVID-19 [DOI] 10.1155/2021/4688764 PMC 바로가기 [Article Type] Case Series
Pan-selectin inhibitors as potential therapeutics for COVID-19 treatment: in silico screening studyCOVID-19 치료를 위한 잠재적 치료제로서의 Pan-selectin 억제제: in silico 스크리닝 연구Article Published on 2021-09-092022-09-11 Journal: Glycobiology [Category] SARS, 신약개발, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome anti-cytokine anti-cytokine therapy antivirals approved drugs binding Blood carbohydrate Cell Compound compounds coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 therapeutics cytokine response Cytokine storm Cytokines death described develop disease docked docking domain E-selectin early response effective Evidence globe hospitalized patient hospitalized patients in silico induce Inflammatory cytokine Inflammatory cytokines inflammatory disease Inflammatory diseases Inflammatory response inhibitor inhibitors leukocyte Ligand ligands Migration Mortality overactive overproduction pan-selectin inhibitors Pathogenesis Proinflammatory cytokine proinflammatory cytokines protease inhibitors respiratory distress Respiratory failure screened screening procedure selectin selectins Spectrum Spread syndrome therapeutic target tissue Treatment treatment of COVID-19 Vaccine Virtual screening with COVID-19 Zinc ZINC database [DOI] 10.1093/glycob/cwab021 PMC 바로가기 [Article Type] Article
Snowball Sampling Study Design for Serosurveys Early in Disease Outbreaks질병 발생 초기 혈청 처리를위한 눈덩이 샘플링 연구 설계Observational Study Published on 2021-09-082022-09-10 Journal: American journal of epidemiology [Category] 임상, 치료기술, [키워드] Analysis association Asymptomatic asymptomatic infection asymptomatic infections capture Characteristics Contact Contact tracing coronavirus disease Coronavirus disease 2019 COVID-19 design effect disease severity early stage early stages estimation Evidence evidence of Host individuals infected cases Infection infection rate information observational study outbreak pandemic Pandemics parameters Probability proportion question Sample size sampling SARS-CoV-2 serological survey Serological surveys seropositive Seropositivity serosurvey sampling Snowball Spectrum Study design transmission chain [DOI] 10.1093/aje/kwab098 PMC 바로가기 [Article Type] Observational Study
COVID-19 susceptibility variants associate with blood clots, thrombophlebitis and circulatory diseasesCovid-19 감수성 변이체는 혈전, 혈전증 및 순환 질환과 관련이 있습니다.Research Article Published on 2021-09-032022-09-10 Journal: PLoS ONE [Category] SARS, 변종, 유전자 메커니즘, [키워드] adverse outcome adverse outcomes Analysis approach association Blood blood clot Blood clots comorbid condition comorbid conditions COVID-19 COVID-19 susceptibility diabetes disease Effects epidemiological studies evaluated event General practice Genome-wide association studies higher risk Hospital Episode Statistics identify increased risk individual Inflammatory loci lung Lungs other disease other diseases outcomes performed phenotypic data phlebitis phlebitis and thrombophlebitis Practice Predictive reported risk severity Spectrum Stratification susceptibility thrombophlebitis traits UK biobank utilised variant vascular disease [DOI] 10.1371/journal.pone.0256988 PMC 바로가기 [Article Type] Research Article
A comprehensive analysis of the efficacy and safety of COVID-19 vaccinesCOVID-19 백신의 유효성 및 안전성에 대한 포괄적인 분석Meta-Analysis Published on 2021-09-012022-09-11 Journal: Molecular therapy : the journal of the American So [Category] MERS, SARS, 변종, 임상, 진단, [키워드] addition addressed ADR ADRS Adverse Adverse drug reaction Adverse drug reactions African American black can be used comprehensive analysis coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines death doses Efficacy Efficacy and safety exceeded fatigue Grade 1 greater headache highest male MOST myocarditis Pain performed Pericarditis powerful tool reaction Reactions real-world data Reporting Research Safety SARS-CoV-2 severity Spectrum System the vaccine the vaccines thromboembolic Thromboembolic events tolerable Trial vaccination Vaccine [DOI] 10.1016/j.ymthe.2021.08.001 PMC 바로가기 [Article Type] Meta-Analysis
Ways to Address Perinatal Mast Cell Activation and Focal Brain Inflammation, including Response to SARS-CoV-2, in Autism Spectrum DisorderReview Published on 2021-08-292022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] ACE2 activated Activation address affected allergens allergies Amygdala angiotensin-converting enzyme 2 anti-inflammatory cytokine approach ASD association Asthma atopic dermatitis autism Autism Spectrum Disorder binding block Brain changes children Comorbidity complicate COVID-19 Cytokines Deceased decreased expression disorder disrupting drug effective electrical Epidemiological study expression flavonoids Focal gestation IL-18 increased expression Inflammation Inflammatory inhibit inhibitor Luteolin mast cell Mast cells microglia mother neurodegenerative neuronal Pathogenesis Patient Perinatal Pregnancy Prevalence Proinflammatory cytokine receptor regulate reported response SARS-CoV-2 Spectrum Stress threshold tissue toxins Treatment triggered virus [DOI] 10.3390/jpm11090860 PMC 바로가기 [Article Type] Review
Mutational spectrum of SARS-CoV-2 during the global pandemic세계적 대유행 동안 SARS-CoV-2의 돌연변이 스펙트럼Article Published on 2021-08-272022-09-10 Journal: Experimental & Molecular Medicine [Category] MERS, SARS, 변종, [키워드] accumulate Analysis Asia base collected collection time coronavirus COVID-19 pandemic cytosine directional ENhance equilibrium Evidence evidence of Evolution Evolutionary biology exhibit extreme genetic material Genome Genome evolution genome sequence global pandemic guanine help human population information interactions monitoring much higher Mutation mutational processe mutational processes mutational spectrum natural selection nucleic acid predict reached replaced REPLACED BY researcher responsible SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 mutations SARS-CoV-2 viral infection SARS-CoV-2 virus Science sequence South Korea Spectrum substitutions technology the SARS-CoV-2 genome the SARS-CoV-2 virus Transmission uracil Viral viral genes viral genome sequence viral genome sequences viral infection Viral transmission virus viruses was performed [DOI] 10.1038/s12276-021-00658-z PMC 바로가기 [Article Type] Article
Clinical Spectrum and Neuroimagistic Features in Hospitalized Patients with Neurological Disorders and Concomitant Coronavirus-19 InfectionArticle Published on 2021-08-272022-10-28 Journal: Brain Sciences [Category] COVID-19, [키워드] abnormality age Anosmia Anxiety association biochemical evaluation biochemical parameter blood glucose C-reactive protein cerebral hemorrhage cerebrovascular clinical Complication Concomitant correlated COVID-19 COVID-19 infection COVID-19 pandemic Cranial nerve D-dimer Department Depression determine diagnosed Dizziness early stage enrolled erythrocyte sedimentation rate ESR event Evidence facial nerve palsy Features fibrinogen hospitalized patients hsCRP in both group in both groups Infection lactate dehydrogenase LDH less lung damage mechanism men much higher Neurological disorder Neurological disorders neurological manifestation NEUROLOGY Neuropsychiatric occurred Patient Prognosis protocol representing Research Retrospective study Severe COVID-19 Infection significantly Spectrum statistically stroke Symptom the disease thrombosis venous was increased [DOI] 10.3390/brainsci11091138 PMC 바로가기 [Article Type] Article
COVID-19 and Co-infection in Children: The Indian PerspectivesCOVID-19와 어린이의 동시 감염: 인도의 관점Observational Study Published on 2021-08-272022-09-11 Journal: Journal of tropical pediatrics [Category] SARS, 임상, 치료기술, [키워드] Admission age analyzed Assessing Blood blood culture Care characterized clinical impact Co-infection concurrent conducted COVID COVID-19 COVID-19 infection COVID-19 patient CRP CSF Culture demonstrated determine Early detection etiology group growth Hyperferritinemia Infection information laboratory parameter Laboratory parameters Localization lymphopenia methicillin moderate moderate to severe morbidity neutrophil neutrophil count observational study pediatric Pediatric patient Pediatric patients prevalent prospective observational study recorded respiratory viral infection respiratory viral infections RT-PCR scrub typhus secretion serology severe disease significantly higher Spectrum Staphylococcus aureus study population subset supportive therapy therapy Treatment variable viral infections with COVID-19 [DOI] 10.1093/tropej/fmab073 PMC 바로가기 [Article Type] Observational Study