Extracellular Vesicles: Versatile Nanomediators, Potential Biomarkers and Therapeutic Agents in Atherosclerosis and COVID-19-Related Thrombosis세포외 소포: 죽상경화증 및 COVID-19 관련 혈전증에서 다목적 나노매개체, 잠재적 바이오마커 및 치료제Review Published on 2021-05-312022-09-10 Journal: International Journal of Molecular Sciences [Category] 바이오마커, [키워드] agent atherogenesis Atherosclerosis atherosclerotic Biomarker Biomarkers cardiovascular disease cardiovascular diseases cargo Cell cells Characteristics coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient cytoplasmic proteins DNA Effect endocytosis endothelial EVs Exosomes extracellular vesicle Extracellular vesicles immune cells information mechanism mediators Mesenchymal stromal cells metabolites microRNA Microvesicles mRNA participant pathological condition Pathologies Platelets Potential receptors Signaling stromal cells therapeutic agents therapeutic potential thrombosis thrombotic Thrombotic events transfer variety [DOI] 10.3390/ijms22115967 PMC 바로가기 [Article Type] Review
Comparison of clinical features and outcomes in COVID-19 and influenza pneumonia patients requiring intensive care unit admissionOriginal Paper Published on 2021-05-262022-10-29 Journal: Infection [Category] COVID-19, MERS, SARS, [키워드] 30-Day mortality Admission bacterial superinfection bacterial superinfections Care chronic Chronic kidney disease CKD clinical feature COPD Coronavirus disease-19 COVID-19 COVID-19 patient critically ill patients evaluate Factor ICU ICU admission identify Influenza influenza pneumonia intensive care intensive care unit invasive Invasive pulmonary aspergillosis IPA Laboratory lymphocyte male Male sex median age Mortality multivariable analysis outcome Patient patients with COVID-19 Pneumonia pulmonary Result risk Rome SARS-CoV-2 significantly significantly higher significantly lower SOFA score Superinfections thrombotic event Thrombotic events Umberto unit with COVID-19 [DOI] 10.1007/s15010-021-01624-7 PMC 바로가기 [Article Type] Original Paper
Effect of aspirin on short-term outcomes in hospitalized patients with COVID-19Original Research Articles Published on 2021-05-192022-10-28 Journal: Vascular Medicine (London, England) [Category] COVID-19, SARS, [키워드] ACE2 affected Analysis antiplatelet Aspirin caused cerebrovascular accident Coronavirus disease 2019 COVID-19 death in COVID-19 determine Effect elevated evaluated hospitalized patient increased risk mechanism mitigate Mortality Myocardial infarction nonsteroidal anti-inflammatory drug NSAID NSAIDS outcome pandemic performed Platelet Platelets Prevent risk SARS-CoV-2 symptomatic patient tested thrombosis thrombotic Thrombotic events thrombotic risk TMPRSS2 Treatment utility Venous Thromboembolism with COVID-19 [DOI] 10.1177/1358863X211012754 PMC 바로가기 [Article Type] Original Research Articles
The Relationship between Inflammatory Cytokines and Coagulopathy in Patients with COVID-19Article Published on 2021-05-092022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] abnormal coagulation Abnormalities abnormality accompanied Admission Alpha Anti-inflammatory Anticoagulant association baseline clinical Clinical outcome Coagulation coagulation parameter Coagulopathy consecutive patient Consequences Coronavirus disease 2019 Course COVID-19 cytokine level Cytokine storms Cytokines death decrease disease Features Hospitalization Hospitalized hypercoagulability hyperinflammation IL-1 IL-6 increased risk Inflammation Inflammatory cytokine Inflammatory cytokines Laboratory morbidity and mortality Necrosis outcome parameters patients prevalent relationship SARS-CoV-2 selected thrombosis thrombotic event Thrombotic events TNF-α were measured were recorded with COVID-19 [DOI] 10.3390/jcm10092020 PMC 바로가기 [Article Type] Article
Immunothrombosis in COVID-19: Implications of Neutrophil Extracellular TrapsCOVID-19의 면역혈전증: 호중구 세포외 트랩의 의미Review Published on 2021-05-062022-09-01 Journal: Biomolecules [Category] SARS, 바이오마커, 진단, [키워드] Activation activation pathway acute phase reactant acute phase reactants analyzed Bacterial causative agent Cell CID clinical manifestation clinical manifestations Coagulation coronavirus COVID-19 COVID-19 pandemic CRP D-dimer Disseminated intravascular coagulation DNA elevated etiological Extracellular family fungal hospitalized patient hospitalized patients immunothrombosis include increased risk infection control Inflammatory mediators innate immune response Interaction interleukin intravascular coagulation involved Kidney disease Lactate lactate dehydrogenase leads marker mechanism member Mortality MPO NET NETs neutrophil Neutrophil extracellular traps Neutrophils outbreak patients with COVID-19 Previous studies previous study Recognition recruit respiratory Respiratory disease respiratory diseases SARS-CoV-2 severe COVID-19 severe disease shown thrombotic thrombotic event Thrombotic events total neutrophil count Vascular Viral with COVID-19 [DOI] 10.3390/biom11050694 PMC 바로가기 [Article Type] Review
Thromboelastography findings in critically ill COVID-19 patientsArticle Published on 2021-05-012023-06-19 Journal: Journal of Thrombosis and Thrombolysis [Category] MERS, SARS, [키워드] COVID-19 critically ill patients Hypercoagulable state Thromboelastography (TEG) Thromboembolism Thrombotic events [DOI] 10.1007/s11239-020-02300-7 PMC 바로가기
Rationale and design for the study of rivaroxaban to reduce thrombotic events, hospitalization and death in outpatients with COVID-19: The PREVENT-HD studyClinical Trial Published on 2021-05-012022-10-05 Journal: American heart journal [Category] 임상, [키워드] 1:1 all-cause hospitalization all-cause mortality Anticoagulant anticoagulation approach bleeding Clinical trial design COVID-19 Critical death double-blind Effectiveness Efficacy and safety efficacy end point end point evaluate events expected Hospitalization hospitalized patient Ischemia laboratory-confirmed limb Mortality Myocardial infarction nervous system Outpatient pandemic participant phase 3 trial Placebo placebo-controlled Pragmatic Prophylactic Randomized rationale reduce required risk Society stratified stroke symptomatic Thromboprophylaxis Thrombotic complications Thrombotic events Trial venous Venous Thromboembolism while with COVID-19 [DOI] 10.1016/j.ahj.2021.02.001 PMC 바로가기 [Article Type] Clinical Trial
Editorial: SARS-CoV-2 mRNA Vaccines and the Possible Mechanism of Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT)사설: SARS-CoV-2 mRNA 백신과 백신 유발 면역 혈전성 혈소판 감소증(VITT)의 가능한 메커니즘Editorial Published on 2021-04-262022-09-11 Journal: Medical science monitor : international medical jo [Category] SARS, 유전자 메커니즘, 임상, [키워드] antibody AstraZeneca Autoimmune cavernous sinus cavernous sinus thrombosis ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine clinical trials collaboration coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-react death rate editorial Efficacy global pandemic heparin heparin-induced thrombocytopenia Hope morbidity mRNA mRNA vaccine Oxford Platelet platelet factor 4 Prevent safety profile SARS-CoV-2 SARS-CoV-2 spike Science Sinus thrombosis Spread syndrome the SARS-CoV-2 thrombocytopenia thrombosis thrombotic thrombotic event Thrombotic events University of Oxford vaccination virus women [DOI] 10.12659/MSM.932899 PMC 바로가기 [Article Type] Editorial
Thrombotic Events in COVID-19 Are Associated With a Lower Use of Prophylactic Anticoagulation Before Hospitalization and Followed by Decreases in Platelet ReactivityMedicine Published on 2021-04-222022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval adjusted odds ratio ADP age all-cause mortality AOR association Asthma baseline blood sample clinical Clinical outcome control patient COVID-19 COVID-19 negative COVID-19 positive patient decrease determine develop disease enrolled expression flow cytometry followed by highlight Hospitalized hospitalized COVID-19 patient hypercoagulability incidence increased the risk less Lower nine Non-survivors outcome P-selectin Patient Platelet Platelets positive prothrombotic state provided pulmonary thrombosis reactivity retrospective cohort study risk SARS-CoV-2 significant difference survivor therapy Thromboinflammation Thromboprophylaxis thrombosis thrombotic thrombotic event Thrombotic events was determined with COVID-19 [DOI] 10.3389/fmed.2021.650129 PMC 바로가기 [Article Type] Medicine
Getting to the Heart of the Matter: Myocardial Injury, Coagulopathy, and Other Potential Cardiovascular Implications of COVID-19Review Article Published on 2021-04-222022-10-30 Journal: International Journal of Vascular Medicine [Category] COVID-19, [키워드] Analysis arrhythmia cardiac damage cardiovascular cardiovascular complication cardiovascular complications cardiovascular disease cause Coagulation Coagulopathy Complication complications complications of COVID-19 Continuous coronary syndrome COVID COVID-19 COVID-19 infection D-dimer develop endothelial fibrosis Follow-up heart heart failure include increase Infarction Inflammation Inflammatory Injury literature review myocardial injury myocarditis Other Pathogenesis Patient peptide physician Potential presenting Prevent primary care protocol Respiratory illness risk serum severity of COVID-19 Shock Stress stroke syndrome the patient Thrombotic events Vascular venous ventricular was performed [DOI] 10.1155/2021/6693895 PMC 바로가기 [Article Type] Review Article