Understanding the genetic determinant of severity in viral diseases: a case of SARS-Cov-2 infection
Review
[키워드] Abstract
ACE2
Admission
Affect
age
Angiotensin-converting enzyme 2 (ACE2) gene
Asymptomatic
Clinical outcome
clinical response
clinical variability
co-morbidity
condition
contribute
coronavirus
COVID-19
Diagnosis
disease
disease severity
effort
Factor
Factors
Genetic
help
HLA
human gene
Human genetics
Human leucocyte antigen (HLA) allele
hypothetical
ICU
identify
in viral
increased risk
Infection
intensive care
life threatening
mild infection
Mutation
Numerous
occur
outbreak
outcome
pandemic
Patient
Prophylaxis
question
reported
Research
SARS-CoV-2
Severe infection
severity
shown
significantly
susceptibility
target
the disease
the SARS-CoV-2
therapy
TLR
TLR3
TLR7
Toll-like receptor (TLR)
understanding
unique
variant
Variation
viral infection
viral infections
[DOI] 10.1186/s43042-020-00122-z PMC 바로가기 [Article Type] Review
[DOI] 10.1186/s43042-020-00122-z PMC 바로가기 [Article Type] Review