The Plasmodium falciparum Cell-Traversal Protein for Ookinetes and Sporozoites as a Candidate for Preerythrocytic and Transmission-Blocking Vaccines플라스모디움 팔시파룸의 우키네트 및 스포로조이트 세포 통과 단백질: 전적혈구 및 전파 차단 백신 후보Article Published on 2016-11-282024-08-12 Journal: Infection and Immunity [Category] 말라리아, [키워드] CelTOS malaria parasite transgenic Vaccine [DOI] 10.1128/IAI.00498-16 PMC 바로가기
Development of transgenic mouse model expressing porcine aminopeptidase N and its susceptibility to porcine epidemic diarrhea virusArticle Published on 2014-12-272022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] aminopeptidase N animal model APN bovine coronavirus Coronavirus infection Coronaviruses development epidemic diarrhea expressed expressing fusing growth hormone Infection Laboratory mice organs Pathogenesis polyadenylation site Porcine APN Porcine coronaviruses Porcine epidemic diarrhea virus promoter proximal Research respiratory diseases susceptibility susceptible transgene transgenic transgenic mice Transgenic mouse transgenic mouse model virus [DOI] 10.1016/j.virusres.2014.12.024 PMC 바로가기 [Article Type] Article
Digital Genotyping of Macrosatellites and Multicopy Genes Reveals Novel Biological Functions Associated with Copy Number Variation of Large Tandem RepeatsMacrosatellites 및 Multicopy 유전자의 디지털 유전형 분석은 대규모 직렬 반복의 복사 수 변화와 관련된 새로운 생물학적 기능을 나타냅니다.Research Article Published on 2014-06-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accompanied accumulation accumulations Analysis approach approaches association Biological Biological functions changes in copy copy number correlation Digital DNA methylation DNA methylation levels Effect Effects eukaryotic Evolution example expansion extreme FIVE focus fraction function functional Gene Expression Genes Genome genome assembly Genome-wide association study genomes genomic Genotype GWAS hallmark hallmarks human population human populations humans identify include information lead Local loci majority mechanism modulating non-human primates novel nucleotide number Organisms phenotypic diversity Population Previous studies Repeat repeated selective selective pressure sequence significantly single nucleotide single nucleotide variation SNP SNPs suppression tandem tandem repeat tandem repeats transgenic utility Variability variant variants Variation variations [DOI] 10.1371/journal.pgen.1004418 PMC 바로가기 [Article Type] Research Article
Two step male release strategy using transgenic mosquito lines to control transmission of vector-borne diseasesarticle Published on 2014-04-302024-09-01 Journal: Family process [Category] 말라리아, [키워드] Dengue malaria transgenic Two step release vector control [Article Type] article
Arabidopsis thaliana RESISTANCE TO FUSARIUM OXYSPORUM 2 Implicates Tyrosine-Sulfated Peptide Signaling in Susceptibility and Resistance to Root InfectionArabidopsis thaliana FUSARIUM OXYSPORUM 2에 대한 내성은 뿌리 감염에 대한 감수성과 내성에 티로신-황산염 신호 전달을 의미합니다Research Article Published on 2013-05-232022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] acting Affect Arabidopsis thaliana Diversity downregulate effector explain expression Extracellular Fusarium Gene Genes host immunity induce Infection inhibit lethal leucine loci locus mutant mutants negative feedback pathogen-specific peptide plant promote Protein provide QTLs Quantitative receptor Regulation related relative susceptibility replaced resistance root Signaling Support suppresse susceptibility traits transgenic tyrosine Vascular while [DOI] 10.1371/journal.pgen.1003525 PMC 바로가기 [Article Type] Research Article
Identification of Orch3 , a Locus Controlling Dominant Resistance to Autoimmune Orchitis, as Kinesin Family Member 1C자가면역 고환염에 대한 지배적인 내성을 제어하는 유전자좌인 Orch3의 확인, 키네신 계열 구성원 1CResearch Article Published on 2012-12-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] a major adjuvants allele alleles animal model Antigen antigen presenting cell antigen presenting cells approach Author Autoimmune Autoimmune disease autoimmune disease susceptibility Autoimmune diseases Autoimmunity autologous characterization chromosome chromosome 11 controlling demonstrated disease disease susceptibility dominant encodes gene etiology exhibiting expression family family member Gene Genetic genetic determinant Genetic predisposition Genome histocompatibility complex identification immunization individual gene individual genes inflammatory disease Kif1c KIF21B KIF5A Kinesin leads loci locus major histocompatibility complex mapped member MHC MHC class MHC class II mice non-infectious orchitis over-expression polymorphism Polymorphisms proliferative Quantitative quantitative trait locus reduced required resistance resistant allele strain susceptibility susceptible T cell T cell responses transcriptional regulation transgenic variety [DOI] 10.1371/journal.pgen.1003140 PMC 바로가기 [Article Type] Research Article