VEGF – Page 7 – Communicable Diseases Research

A whole blood test to measure SARS-CoV-2-specific response in COVID-19 patients

Original Article

Published on 2020-10-102022-10-04
Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 진단,

[키워드] Abstract Activation Antigen approach characterized CMV COVID-19 COVID-19 patient diagnostic diagnostic test disease endothelial Enterotoxin evaluated expressed FGF fibroblast G-CSF GM-CSF granulocyte-colony stimulating factor growth factor IFN-γ IFN-γ IL-10 IL-12p70 IL-13 IL-15 IL-17A IL-1ra IL-2 IL-4 IL-5 IL-6 IL-7 IL-8 IL-9 Image immune response individual inflammatory protein interferon IP-10 Macrophage MCP-1 median MIP-1β monocyte chemoattractant protein-1 Multiplex analysis Necrosis objective parameters Patient PDGF peptide platelet-derived growth factor Protein RANTES regulated Result SARS-CoV-2 SARS-CoV-2 peptide SEB secreted Serology response significantly increased Specific response T cell T-cell T-cell based tests Th1 Th2 TNF-α Vaccine Vascular VEGF Whole blood with COVID-19
[DOI] 10.1016/j.cmi.2020.09.051 PMC 바로가기 [Article Type] Original Article

Systems Pharmacology and Verification of ShenFuHuang Formula in Zebrafish Model Reveal Multi-Scale Treatment Strategy for Septic Syndrome in COVID-19

Pharmacology

Published on 2020-09-152022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] affected AKR1B10 Analysis Bacterial Chinese Clinical treatment coagulation disorder complementary Compound coronavirus disease COVID-19 COVID-19 patient deficiency develop disease Effect ENhance ESR1 Evidence exhibited expression Formula immune immune dysfunction immune gene IMPROVE in viral Inflammatory inhibited investigated involved Macrophage MAPK MAPK14 metabolic disease Model network neutrophil outbreak phagocytosis pharmacological Pharmacology PPARG provided PTGS2 receptor reducing Result Sepsis septic signaling pathway significantly Strategy syndrome System Systems pharmacology target targets therapy Thrombus Toll-like receptors Traditional Chinese medicine treating COVID-19 patient Treatment VEGF verification viral infection Wuhan zebrafish
[DOI] 10.3389/fphar.2020.584057 PMC 바로가기 [Article Type] Pharmacology

Intussusceptive angiogenesis in Covid-19: hypothesis on the significance and focus on the possible role of FGF2

Short Communication

Published on 2020-09-122023-06-15
Journal: Molecular biology reports [Category] MERS,

[키워드] Angiogenesis COVID-19 FGF2 Intussusceptive VEGF virus
[DOI] 10.1007/s11033-020-05831-7 PMC 바로가기 [Article Type] Short Communication

SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosis

Research

Published on 2020-07-142022-10-28
Journal: Respiratory Research [Category] COVID-19, SARS,

[키워드] ACE2 activate acute lung injury acute respiratory syndrome ADAM17 Affect AGT angiotensin-converting enzyme 2 assist bind binding bioinformatic analysis cellular receptor change cleaved connective tissue coronavirus COVID-19 CTGF dataset disease domain driver endothelial enzyme epithelial cell FN1 growth factor host cells human epithelial cell human lung induce Lung epithelial cells Lung fibrosis lung tissue mechanism metalloproteinase mRNA pandemic disease patients promote Protein protein expression Result SARS-CoV-2 SARS-COV-2 infection specific treatment TGFB1 Tissue Inhibitor TMPRSS2 transcriptional transmembrane serine protease Vascular VEGF viral entry were expressed were measured
[DOI] 10.1186/s12931-020-01445-6 PMC 바로가기 [Article Type] Research

Overview: Systemic Inflammatory Response Derived From Lung Injury Caused by SARS-CoV-2 Infection Explains Severe Outcomes in COVID-19

Immunology

Published on 2020-06-262022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS,

[키워드] ACE2 Activation acute lung injury acute phase response acute respiratory distress Adhesion Molecule alveolar macrophage ARDS Bisphosphonates Blood Bone marrow Cell Combination COVID-19 CSS cytokine Cytokine storm syndrome decrease develop dissemination Endothelium expression Factors fibrinogen IL-1β IL-6 immature Impact increase infiltration of neutrophil Inflammation Inflammatory inflammatory monocytes Intervention Kallikrein-kinin system knowledge lung lung epithelial cell Lung infection Lung injury Monocytes MOST patients Platelets pro-thrombotic proinflammatory cytokines reducing renin-angiotensin system response SARS-CoV-2 SARS-CoV2 SARS-CoV2 infection severe COVID-19 stimulate syndrome systemic systemic inflammation TNF VEGF
[DOI] 10.3389/fimmu.2020.01626 PMC 바로가기 [Article Type] Immunology

HIF-1α is involved in blood–brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis

HIF-1α는 폐렴구균 수막염에서 혈액-뇌 장벽 기능 장애와 세포 간 박테리아 이동에 관여한다.

Original Paper

Published on 2020-06-112024-07-31
Journal: Acta Neuropathologica [Category] 폐렴구균 감염증,

[키워드] blood–brain barrier (BBB) Dexamethasone Endothelium HIF-1α Meningitis Paracellular transmigration permeability S. pneumoniae VEGF
[DOI] 10.1007/s00401-020-02174-2 PMC 바로가기 [Article Type] Original Paper

Blocking CD47 efficiently potentiated therapeutic effects of anti-angiogenic therapy in non-small cell lung cancer

Research Article

Published on 2019-12-112023-08-30
Journal: Journal for immunotherapy of cancer [Category] E형 간염,

[키워드] anti-angiogenesis Bispecific therapy CD47 Immunotherapy VEGF
[DOI] 10.1186/s40425-019-0812-9 PMC 바로가기 [Article Type] Research Article

Tumor angiogenesis: causes, consequences, challenges and opportunities

Review

Published on 2019-11-062023-08-30
Journal: Cellular and Molecular Life Sciences [Category] E형 간염,

[키워드] Angiogenesis anti-angiogenic therapy Cancer endothelial Vascular targeting VEGF
[DOI] 10.1007/s00018-019-03351-7 PMC 바로가기 [Article Type] Review

Baseline Absolute Lymphocyte Count and ECOG Performance Score Are Associated with Survival in Advanced Non-Small Cell Lung Cancer Undergoing PD-1/PD-L1 Blockade

Article

Published on 2019-07-102023-08-30
Journal: Journal of Clinical Medicine [Category] E형 간염,

[키워드] Absolute lymphocyte count Antibiotics Denosumab ECOG performance status immune-checkpoint blockade immune-checkpoint inhibitor PD-1/PD-L1 RANK VEGF
[DOI] 10.3390/jcm8071014 PMC 바로가기 [Article Type] Article

Induction of Angiogenesis by Malarial Infection through Hypoxia Dependent Manner

article

Published on 2019-04-302024-09-01
Journal: The Korean Journal of Parasitology [Category] 말라리아,

[키워드] Angiogenesis HIF1α hypoxia malaria Plasmodium berghei VEGF
[Article Type] article