Severe Acute Respiratory Syndrome Coronavirus-2 Inactivation Activity of the Polyphenol-Rich Tea Leaf Extract with Concentrated Theaflavins and Other Virucidal Catechins중증 급성 호흡기 증후군 코로나바이러스-2 농축 테아플라빈 및 기타 바이러스성 카테킨을 함유한 폴리페놀이 풍부한 찻잎 추출물의 불활성화 활성Article Published on 2021-08-082022-09-10 Journal: Molecules [Category] MERS, SARS, 치료제, [키워드] absence activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed auxiliary catechin Cell Cell culture cell culture medium cells coronavirus culture media culture medium death ENhance evaluate evaluated Extract Genome Impact in vitro incubated Incubation Infection inhibited inhibition activity leaf Measures media Other polyphenol producing provided real-time RT-PCR replaced respiratory RT-PCR S protein S2 subunit SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus structural protein structural proteins suggested tea tea leaf extract the cell the cells the S protein theaflavin Treatment Ty-1 Viral viral genome Viral protein Viral proteins Viral RNA viral titer viral titers virucidal virucidal activity western blotting [DOI] 10.3390/molecules26164803 PMC 바로가기 [Article Type] Article
Supporting scale-up of COVID-19 RT-PCR testing processes with discrete event simulation개별 이벤트 시뮬레이션으로 COVID-19 RT-PCR 테스트 프로세스의 확장 지원Research Article Published on 2021-07-292022-09-12 Journal: PLoS ONE [Category] MERS, 진단, [키워드] Analysis bottleneck bottlenecks change COVID-19 COVID-19 pandemic Critical equipment evaluate example expand facilitate feasible identify inhibited Intervention Isolation Laboratory medium molecular pandemic partnership PCR testing problem public health emergency required RT-PCR testing Safe SARS-CoV-2 RT-PCR state Support Supporting Swab swabs Testing the United State time-consuming trade-off trade-offs United States university Variability virucidal [DOI] 10.1371/journal.pone.0255214 PMC 바로가기 [Article Type] Research Article
Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2Article Published on 2021-07-232022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] 405 nm blue light absence acute respiratory syndrome blue Combination coronavirus determine Disinfection effective Efficacy far-UVC Feline infectious peritonitis virus inactivation individual LIGHT light disinfection Model occur pandemic peritonitis reduction required respiratory droplet Saliva SARS-CoV-2 ultraviolet light viral inactivation virucidal virus wavelength Wet [DOI] 10.3390/v13081436 PMC 바로가기 [Article Type] Article
Solar UV-B/A radiation is highly effective in inactivating SARS-CoV-2Article Published on 2021-07-202022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] Atmospheric science average characteristic Concentration diffusion earth effective Epidemics Epidemiology intensity less lower mortality Mortality mortality data outbreak Pandemics Radiation recorded Region SARS-CoV-2 single-stranded RNA virus Single-stranded RNA viruses Solar Solar physics TCID the SARS-CoV-2 UV light virion virucidal virus viruses [DOI] 10.1038/s41598-021-94417-9 PMC 바로가기 [Article Type] Article
Methylene Blue has a potent antiviral activity against SARS-CoV-2 and H1N1 influenza virus in the absence of UV-activation in vitro메틸렌 블루는 시험 관내 UV- 활성화의 부재하에 SARS-COV-2 및 H1N1 인플루엔자 바이러스에 대한 강력한 항 바이러스 활성을 갖는다.Article Published on 2021-07-122022-09-01 Journal: Scientific Reports [Category] SARS, 유전자 메커니즘, 진단, 치료제, [키워드] absence Activation addition antiviral activity Antiviral agents approved blood product blood products blue Cell Clinical studies clinical study Concentration Degradation drug effective EMA European Medicines Agency evaluated examined FDA food genomic RNA H1N1 H1N1 influenza immune Immune Serum in vitro infected with SARS-CoV-2 Influenza influenza virus H1N1 malaria mechanism methemoglobinemia Methylene Methylene blue presence or absence safety profile SARS-CoV-2 SARS-CoV-2 infections serum shown Support therapeutic activity therapeutic efficacy Treatment UV light viral infection virucidal virus viruses [DOI] 10.1038/s41598-021-92481-9 PMC 바로가기 [Article Type] Article
Efficacy of “Essential Iodine Drops” against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)중증 급성 호흡기 증후군-코로나 바이러스 2 (SARS-COV-2)에 대한 "필수 요오드 방울"의 효능Research Article Published on 2021-07-092022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료제, [키워드] 1:1 aerosolization aqueous solution ATCC CCID Cell Cell culture complex controls coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients CPE Cytopathic effect demonstrated Dilution drop effective end-point dilution Essential evaluated fulvic acid in vitro infecting infectious dose intranasal intranasally Iodine pandemic povidone-iodine Prevent quantified reduce reduced reducing reductions in respiratory respiratory droplet Respiratory droplets Result room temperature SARS-CoV-2 SARS-CoV-2 transmission SARS-CoV-2 viral SARS-CoV-2 virus Severe acute respiratory syndrome Spread temperature titre titres Vero Viral Viral load virucidal virus virus stock viruses was reduced was tested [DOI] 10.1371/journal.pone.0254341 PMC 바로가기 [Article Type] Research Article
Therapeutic and Industrial Applications of Curdlan With Overview on Its Recent PatentsNutrition Published on 2021-06-282022-10-31 Journal: Frontiers in Nutrition [Category] COVID-19, [키워드] β-(1,3)-glucan oligosaccharides acute respiratory syndrome addition Aede Agrobacterium anti-cancer anti-malaria Anti-viral anticancer Antiviral Antiviral effect application Bacteria Candida cellular and molecular coco composed Coronavirus-2 Curdlan curdlan sulfate demonstrated derivatives dietary supplements disorders drug Effect Effectiveness ENhance exhibited functional functional food fungal Glucose growth Gut healthy help highlight HIV Host Human immunodeficiency virus humans immunomodulatory activity in vivo Industrial information malaria malarial management mechanism of action MERS microbial microbiota Middle East nutraceutical Paenibacillus Patent Prevent problems produced proliferation provide recent reduce Rhizobium Saccharomyces cerevisiae succinoglucan suggested syndrome therapeutic therapeutic intervention therapy Treatment tumor cell virucidal virus viruses [DOI] 10.3389/fnut.2021.646988 PMC 바로가기 [Article Type] Nutrition
Bioactive Polyphenolic Compounds Showing Strong Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus 2Article Published on 2021-06-152022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] activity Antiviral antiviral activity carried clinical study Compound compounds coronavirus 2 COVID-19 Curcumin determine early stage Effectiveness Evidence FDA-approved drug hesperidin Hydroxychloroquine in silico in vitro infections inhibited inhibitors mechanism of action molecular docking Molecular docking study MPro pharmacological protease quercetin receptors respiratory SARS-CoV-2 SARS-CoV-2 Mpro SARS-CoV-2 spike significantly Strong tested therapeutic targeting these compound VERO E6 cells viral infection virucidal virus replication [DOI] 10.3390/pathogens10060758 PMC 바로가기 [Article Type] Article
Effect of various decontamination procedures on disposable N95 mask integrity and SARS-CoV-2 infectivityBasic and Preclinical Research Published on 2021-06-112022-10-30 Journal: Journal of Clinical and Translational Science [Category] COVID-19, [키워드] applied Cell clinical sample COVID-19 COVID-19 pandemic Degradation detectable Effect eliminated experiment feasibility functional help hydrogen peroxide incubated Infection Infectious diseases Mask mask decontamination Masks N95 N95 masks Pathogens Personal protective equipment PROTECT Quantitative Research Respirator reuse RT-PCR SARS-CoV-2 SARS-CoV-2 RNA tested treated Treatment ultraviolet germicidal irradiation ultraviolet light vaporized hydrogen peroxide Vero E6 Vero E6 cell virucidal was tested [DOI] 10.1017/cts.2020.494 PMC 바로가기 [Article Type] Basic and Preclinical Research
Evaluation of virucidal activity of fabrics using feline coronavirusShort Communication Published on 2021-06-102022-11-01 Journal: Journal of virological methods [Category] COVID-19, MERS, SARS, [키워드] In vitro test 2019 coronavirus disease addition ANOVA, one-way Analysis of Variance antiviral activity Antiviral compounds Cell Cell culture Contact coronavirus country COVID-19 COVID-19 transmission COVID-19, 2019 coronavirus disease CPE, cytopathic effect CRFK, Crandell-Rees Feline Kidney Cell D-MEM, Dulbecco's Modified Eagle Medium evaluate examined Fabrics FCoV, Feline coronavirus Health ISO, International Standards Organization Laboratory laboratory technicians organization pandemic Personal protective equipment PPE PPE, Personal protective equipment recommendation reported respiratory responsible RNA virus Safe SARS-CoV-2 SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus type 2 SD, standard deviation significant decrease Standard TCID TCID, Tissue Culture Infectious Dose treated Treatment viral titer virucidal virucidal activity WHO WHO, World Health Organisation [DOI] 10.1016/j.jviromet.2021.114214 PMC 바로가기 [Article Type] Short Communication