Human iPSC-Based Modeling of Central Nerve System Disorders for Drug Discovery
Review
[키워드] Alzheimer’s disease
animal models
appear
approach
astrocytes
Cell
cell type
Clinical efficacy
clinical trials
CNS
CNS disease modeling
contribute
COVID-19
Culture
disease
disease pathogenesis
drug
Drug discovery
exhibiting
Human
identify
in vitro
induced pluripotent stem cells (iPSC)
Interaction
limitation
modeling
nerve
neurons
pathology
Patient
physiological
platform
Precision
provide
responses
System
therapeutic
Therapeutic strategies
three-dimensional cerebral organoids
tissue
toxicity screening
translation
two-dimensional
[DOI] 10.3390/ijms22031203 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/ijms22031203 PMC 바로가기 [Article Type] Review