Traditional Japanese Herbal Medicine Hochu-Ekki-to Promotes Pneumococcal Colonization Clearance via Macrophage Activation and Interleukin 17A Production in Mice전통 일본 한방 약제 호추에끼토가 마우스에서 대식세포 활성화 및 인터루킨 17A 생산을 통해 폐렴구균 집락 제거를 촉진한다.Original Research Published on 2020-10-222024-07-30 Journal: Frontiers in Cellular and Infection Microbiology [Category] 폐렴구균 감염증, [키워드] Hochu-ekki-to (TJ-41) Innate immunity interleukin 17 Macrophage pneumococcal colonization Traditional herbal medicine [DOI] 10.3389/fcimb.2020.569158 PMC 바로가기 [Article Type] Original Research
Innate Immunity and Influenza A Virus Pathogenesis: Lessons for COVID-19Cellular and Infection Microbiology Published on 2020-10-222022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] adverse effect adverse outcome airways disease antimicrobial peptide bacterial superinfection changes in comparison complex COVID 19 COVID-19 Cytokine storm defensin effort evaluate Evidence excessive inflammatory response Factor help Host IAV Infection inflammatory lung injury Inflammatory response Influenza influenza A virus inhibiting inhibitor Innate innate immune response Innate immunity knowledge lesson LL-37 Monocytes morbidity Mortality neutrophil pandemic positive Protein reactive Research SARS-CoV SARS-CoV virus Surfactant protein D treat viral replication virus [DOI] 10.3389/fcimb.2020.563850 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
A Health Economic Analysis for Oral Poliovirus Vaccine to Prevent COVID‐19 in the United States미국에서 COVID-19를 예방하기 위한 경구용 폴리오바이러스 백신에 대한 건강 경제 분석Review Published on 2020-10-202022-09-10 Journal: Risk Analysis [Category] MERS, 임상, 폴리오, [키워드] administer administration American Americans B‐cell benefit clinical trials Containment Coverage COVID‐19 COVID‐19 decision dose Effect effective expected Giving Health health economics highest immunocompromised individual immunocompromised individuals immunodeficiency immunological effect implication induce Infection Innate immunity lack lead new infections nonspecific OPV oral oral poliovirus vaccine paralysis paralytic polio polio poliovirus vaccine Primary immunodeficiencies repeated risk the United State Transmission United States virus viruses widespread [DOI] 10.1111/risa.13614 PMC 바로가기 [Article Type] Review
Twenty years of progress in angiotensin converting enzyme 2 and its link to SARS-CoV-2 diseaseReview Published on 2020-10-162023-07-06 Journal: Clinical Science (London, England : 1979) [Category] SARS, [키워드] Angiotensin II Angiotensin-(1-7) cardiovascular disease chymase coronavirus Innate immunity [DOI] 10.1042/CS20200901 PMC 바로가기 [Article Type] Review
A Testimony of the Surgent SARS-CoV-2 in the Immunological Panorama of the Human HostCellular and Infection Microbiology Published on 2020-10-162022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] ACE-2 receptor Activation acute respiratory distress syndrome (ARDS) adaptive angiotensin-converting enzyme 2 (ACE-2) ARDS Cell Cytokine storm dysregulation evade fatality feature Genetic helping Host host antiviral response Human IFN immunopathology Infection Inflammatory cytokines Innate immunity Making manifested MERS-CoV modulate molecular Novel coronavirus pandemic receptor binding domain (RBD) replicating virus robust SARS-CoV SARS-CoV-2 selective Severe case the SARS-CoV-2 TMPRSS2 transmembrane protease serine 2 (TMPRSS2) transmissibility of SARS-CoV-2 unique virus [DOI] 10.3389/fcimb.2020.575404 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Coronaviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and CytokinesReview Published on 2020-10-152023-06-15 Journal: Trends in immunology [Category] MERS, SARS, [키워드] cell death coronavirus COVID-19 Cytokines Inflammasome Inflammation Innate immunity MERS-CoV MHV PANoptosis PANoptosome RNA virus SARS-CoV SARS-CoV-2 [DOI] 10.1016/j.it.2020.10.005 PMC 바로가기 [Article Type] Review
Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agentsReview Published on 2020-10-152022-10-28 Journal: Virology Journal [Category] COVID-19, MERS, SARS, [키워드] activated acute respiratory distress acute respiratory distress syndrome alveolar macrophage angiotensin converting enzyme 2 antibody Antiviral article B cell bind blunt caused characterized China Chloroquine Combination coronavirus 2 Coronavirus disease 2019 COVID-19 COVID-19 illness CRS cytokine Cytokine release syndrome Cytokine storm drug target dysregulation enzyme epithelial cells Fever global pandemic hemodynamic instability hypoxia identify IFN IL-1β immune system immunological mechanism Immunotherapy imperative Innate immunity involved manifestation Necrosis Novel coronavirus nuclear Obstetric organ damage overcome Pathogenesis pathophysiology Patient pediatric Phase 2 Phase 3 receptor reduce respiratory respiratory symptoms responsible resulting SARS-CoV-2 SARS-CoV-2 epidemiology severe COVID-19 Signaling syndrome therapeutic agent therapeutic interventions tissue injury TLR Tocilizumab triggering Viral load viral replication virus Virus-host interaction Virus-host interactions World Health Organization worsening [DOI] 10.1186/s12985-020-01415-w PMC 바로가기 [Article Type] Review
Landscape of coordinated immune responses to H1N1 challenge in humansResearch Article Published on 2020-10-122023-06-14 Journal: The Journal of Clinical Investigation [Category] Fulltext, 신종인플루엔자, [키워드] Adaptive immunity immunology Infectious disease Influenza Innate immunity [DOI] 10.1172/JCI137265 PMC 바로가기 [Article Type] Research Article
Inhibition of SARS-CoV-2 by type I and type III interferonsArticle Published on 2020-10-092023-07-05 Journal: The Journal of Biological Chemistry [Category] SARS, [키워드] antiviral agent COVID-19 cytokine action Infection Innate immunity interferon interferon-alpha/beta Interferon-lambda ruxolitinib SARS–CoV-2 Virology virus [DOI] 10.1074/jbc.AC120.013788 PMC 바로가기
A Systems Biology Workflow for Drug and Vaccine Repurposing: Identifying Small-Molecule BCG Mimics to Reduce or Prevent COVID-19 MortalityArticle Published on 2020-10-062023-07-11 Journal: Pharmaceutical research [Category] SARS, [키워드] bcg vaccine COVID-19 Innate immunity SARS-CoV-2 Systems biology [DOI] 10.1007/s11095-020-02930-9 PMC 바로가기