Analysis of the Genome Sequence and Prediction of B-Cell Epitopes of the Envelope Protein of Middle East Respiratory Syndrome-CoronavirusArticle Published on 2018-07-012022-10-29 Journal: IEEE/ACM transactions on computational biology and [Category] Coronavirus, MERS, [키워드] 3D structure amino acids sequence analyzed B cell epitope B-cell epitope bioinformatics China conserved database death E protein effective envelope epitope genome sequence highly antigenic Host Human identify IMPROVE Infection lack linear B-cell epitope MERS MERS-CoV Middle East NCBI nucleotide outbreak Pandemics Patient PDB predict predicted prediction Protein PyMol respiratory Sequence analysis significantly South Korea strain triggered Vaccine development was performed were used X-ray [DOI] 10.1109/TCBB.2017.2702588 PMC 바로가기 [Article Type] Article
Subtype C ALVAC-HIV and bivalent subtype C gp120/MF59 HIV-1 vaccine in low-risk, HIV-uninfected, South African adults: a phase 1/2 trial저위험 HIV 감염되지 않은 남아프리카 성인을 대상으로 한 아형 C ALVAC-HIV 및 2가 아형 C gp120/MF59 HIV-1 백신: 1/2상 시험Article Published on 2018-06-182022-09-06 Journal: The Lancet. HIV [Category] Communicable Disease, [키워드] 95% CI added adjuvant advancement African allergy Antigen assigned binding antibody CD4+ T-cell changed circulating clinical Community component computer-generated Critical double-blind trial Efficacy enrolled exceeded Express finding foundation funding glycoprotein gp120 HIV HIV infection HIV vaccine HIV-1 HIV-uninfected IgG IgG response immune response immune responses immunogenicity IMPROVE Infectious disease Infectious diseases Intramuscular injection investigators Melinda Gate Melinda Gates MF59 network NIAID outcome participant per-protocol per-protocol analysis Placebo predicted Primary outcomes Protein provided random randomisation randomised controlled Randomly recipient regimen Registered registry reported Research responders response risk significantly higher South South Africa strain Strains subtype T-cell Response tested the vaccine threshold titre Trial vaccination Vaccine Vaccine development was done [DOI] 10.1016/S2352-3018(18)30071-7 PMC 바로가기 [Article Type] Article
Salmonella Typhi Colonization Provokes Extensive Transcriptional Changes Aimed at Evading Host Mucosal Immune Defense During Early Infection of Human Intestinal Tissuearticle Published on 2018-05-312024-09-01 Journal: eBioMedicine [Category] 살모넬라증, [키워드] host-pathogen interaction human tissue immune evasion immune system Innate immunity Intestinal Organoids Organoid monolayer Salmonella Snapwell™ system terminal ileum typhoid fever Vaccine development [Article Type] article
Developmental strategy for a new Group A meningococcal conjugate vaccine (MenAfriVacR)신규 그룹 A 수막구균 결합 백신 (MenAfriVacR) 개발 전략Article Published on 2018-05-042024-08-19 Journal: Human vaccines & immunotherapeutics [Category] 파상풍, [키워드] Group A meningococcal conjugate vaccine Meningitis path SIIPL Vaccine development WHO
T-cell responses against Malaria: Effect of parasite antigen diversity and relevance for vaccine developmentArticle Published on 2018-04-192024-08-28 Journal: Vaccine [Category] 말라리아, [키워드] Antigen diversity malaria T-cell Vaccine development [DOI] 10.1016/j.vaccine.2018.03.023
MERS-CoV: Understanding the Latest Human Coronavirus ThreatReview Published on 2018-02-242022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] Admission Arabian Peninsula Asia Clinical features confirmed cases coronavirus country deaths Diagnosis died Europe Genome HCoV hospital Human human coronavirus humans Infection Jeddah Laboratory Lower respiratory tract lower respiratory tract infections majority MERS-CoV Middle East North Patient presenting renal reported Respiratory failure respiratory syndrome coronavirus respiratory viruses resulting Saudi Arabia severe respiratory illness threat Treatment understanding upper respiratory tract infections Vaccine development [DOI] 10.3390/v10020093 PMC 바로가기 [Article Type] Review
Evaluation of Protective Efficacy of Selected Immunodominant B-Cell Epitopes within Virulent Surface Proteins of Streptococcus pneumoniae폐렴구균의 병원성 표면 단백질 내에서 선택된 면역우세 B세포 에피토프의 보호 효능 평가Article Published on 2018-02-202024-08-24 Journal: Infection and Immunity [Category] 폐렴구균 감염증, [키워드] animal models B-cell epitopes OPKA S. pneumoniae synthetic peptides Vaccine development
Report on WHO meeting on immunization in older adults: Geneva, Switzerland, 22–23 March 2017Article Published on 2018-01-122024-09-04 Journal: Vaccine [Category] 대상포진, [키워드] Ageing global health Immune senescence, World Health Organization immunization Vaccine development [DOI] 10.1016/j.vaccine.2017.12.029 PMC 바로가기 [Article Type] Article
Controlled Human Malaria Infection: Applications, Advances, and ChallengesArticle Published on 2017-12-192024-08-27 Journal: Infection and Immunity [Category] 말라리아, [키워드] Controlled human malaria infection Drug development experimental malaria malaria Plasmodium Vaccine development
Immunogenicity of eGFP-Marked Recombinant Lactobacillus casei against Transmissible Gastroenteritis Virus and Porcine Epidemic Diarrhea VirusArticle Published on 2017-09-252022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] acute diarrhea Administered antibiotic antibiotic-free selection antibody Antigen antigenic site develop effective eGFP epidemic diarrhea evaluated expression fluorescent gastroenteritis IgG immunized immunized mice immunogenicity immunogens Immunoglobulin immunoglobulin A Infection Lactobacillus casei Lymphocytes mice Microscopy mucosal Neutralizing neutralizing effect Oral vaccine PBS PEDV phosphate-buffered saline Porcine epidemic diarrhea virus proliferation Protein provide recombinant reporter resulting S protein Safe secreted serum serum IgG antibody significantly higher TGEV transmissible gastroenteritis virus Vaccine development virus was used were used [DOI] 10.3390/v9100274 PMC 바로가기 [Article Type] Article