Immunomodulatory Role of the Antimicrobial LL-37 Peptide in Autoimmune Diseases and Viral InfectionsReview Published on 2020-09-102022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] AMP AMPs antimicrobial antimicrobial peptide Antiviral approach autoantigen autocrine cascade Cathelicidin cytokine production dendritic cell disease disease pathogenesis disorders dissemination epidermal epithelial cells Express expressed expression Factors immune cells immunomodulatory activity immunomodulatory function increase induce Infection Inflammation initiate Innate immunity interferon limit LL-37 lupus erythematosus macrophages Monocytes Neutrophils paracrine produced progression of disease psoriasis role targeting trauma viral infections virus virus replication [DOI] 10.3390/vaccines8030517 PMC 바로가기 [Article Type] Review
Innate Immune Mechanisms to Protect Against Infection at the Human Decidual-Placental InterfaceReview Published on 2020-09-102024-09-02 Journal: Frontiers in immunology [Category] 대상포진, [키워드] decidua Innate immunity trophoblast uterine-placental interface vertical transmission [DOI] 10.3389/fimmu.2020.02070 PMC 바로가기 [Article Type] Review
On the genetics and immunopathogenesis of COVID-19Review Article Published on 2020-09-102023-07-01 Journal: Clinical immunology (Orlando, Fla.) [Category] SARS, [키워드] Ab, antibody ACE2, angiotensin converting enzyme 2 ADE, antibody dependent enhancement ARDS, Acute Respiratory Disease Syndrome coronavirus CoV, coronavirus COVID-19, Coronavirus disease 2019 CRS, Cytokine release syndrome cytokine GWAS, genome wide association study IFN, type I/III interferons immune response Innate immunity Kawasaki disease MERS, Middle East respiratory syndrome NET, neutrophil extracellular trap SARS-CoV-2 SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 SNP, single nucleotide polymorphism TLR, Toll-like receptor [DOI] 10.1016/j.clim.2020.108591 PMC 바로가기 [Article Type] Review Article
Opinions on the current pandemic of COVID-19: Use functional food to boost our immune functionsReview Article Published on 2020-09-102023-06-15 Journal: Journal of infection and public health [Category] MERS, SARS, [키워드] COVID-19 Innate immunity nutrition SARS-CoV-2 viral infection Zinc [DOI] 10.1016/j.jiph.2020.08.014 PMC 바로가기 [Article Type] Review Article
The New Coronavirus (SARS-CoV-2): A Comprehensive Review on Immunity and the Application of Bioinformatics and Molecular Modeling to the Discovery of Potential Anti-SARS-CoV-2 AgentsReview Published on 2020-09-072022-10-30 Journal: Molecules [Category] COVID-19, SARS, [키워드] agent anti-SARS-CoV-2 application article assist bioinformatics caused Community Comprehensive contribute coronavirus disease Drug discovery Genetic health system Infection Infectious disease Innate immunity involved modeling molecular molecular mechanism Molecular modeling New New coronavirus outbreak pandemic Pathogenesis Potential potential molecular potential therapeutic target provided rapid expansion researcher responsible review SARS-CoV-2 SARS-CoV2 seeking Sequencing Spread Structure target targets the disease the SARS-CoV-2 therapeutic targets Treatment virulence WHO World Health Organization [DOI] 10.3390/molecules25184086 PMC 바로가기 [Article Type] Review
Severe immunosuppression and not a cytokine storm characterizes COVID-19 infectionsResearch Article Published on 2020-09-032022-10-30 Journal: JCI Insight [Category] COVID-19, SARS, [키워드] adaptive Adaptive immunity Administered Blood canonical COVID-19 COVID-19 infection COVID-19 infections COVID-19 patient COVID-19 patients Critically ill cytokine Cytokine storm diagnostic dissemination Elevation ELISPOT evaluate Ex vivo functional healthy control Host host immunity host response Hyperinflammatory hypothese Hypothesis IL-6 level IL-7 immune effector cell immune function immunoassay Immunosuppression immunosuppressive innate immune Innate immunity lack less monocyte mononuclear cell morbidity and mortality organ injury pathologic Patient patients patients with COVID-19 produced proinflammatory cytokines protective immunity reduced restored Sepsis stimulated Support suppresse T cell T cell subset Therapies TNF-α Volunteer [DOI] 10.1172/jci.insight.140329 PMC 바로가기 [Article Type] Research Article
Systemic innate and adaptive immune responses to SARS-CoV-2 as it relates to other coronavirusesArticle Published on 2020-09-022023-06-15 Journal: Human vaccines & immunotherapeutics [Category] MERS, SARS, [키워드] Adaptive immunity COVID-19 Cytokine storm Immunotherapy Innate immunity SARS-CoV-2 [DOI] 10.1080/21645515.2020.1802974 PMC 바로가기
Long-term coexistence of SARS-CoV-2 with antibody response in COVID-19 patientsCOVID-19 환자에서 SARS-CoV-2와 항체 반응의 장기간 공존Article Published on 2020-09-012022-09-11 Journal: Journal of medical virology [Category] MERS, SARS, 바이오마커, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adaptive Adaptive immune response adaptive immune responses Analysis antibody Antibody Response China common clinical symptoms coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient did not produce examined IgG immune responses Immunity Infection Innate immunity Mild Patient patients respiratory SARS-CoV-2 SARS-CoV-2 clearance SARS-COV-2 infection Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus 2 severe symptom severe symptoms shown Spread subset Virus-specific IgG [DOI] 10.1002/jmv.25946 PMC 바로가기 [Article Type] Article
COVID-19 and Vitamin D: A lesson from the skin코로나19와 비타민 D: 피부가 주는 교훈Article Published on 2020-09-012022-09-11 Journal: Experimental dermatology [Category] SARS, 치료제, [키워드] Activation aetiology Anti-inflammatory Antioxidative ARDS calcitriol clinics COVID-19 COVID-19 disease COVID-19 patient CYP11A1 cytokine Cytokine storm Cytokines damage disease distress downregulate Final form High-dose hydroxyl induce infectious agents inhibit Innate immunity Nrf-2 other organ other organs outcome oxidative oxidative stress Patient Population pro-inflammatory cytokines respiratory distress responses SARS-CoV-2 secondary to stimulate supervision Treatment Vitamin Vitamin D vitamin D-hydroxyderivatives. [DOI] 10.1111/exd.14170 PMC 바로가기 [Article Type] Article
Clostridiodes difficile in COVID-19 Patients, Detroit, Michigan, USA, March–April 2020Letters to the Editor Published on 2020-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, SARS, [키워드] 2019 novel coronavirus disease Bacteria Clostridiodes difficile coronavirus coronavirus disease COVID-19 Detroit enteric infections gastrointestinal symptoms IFN-γ IL-12 Innate immunity respiratory infections SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 USA viruses zoonoses [DOI] 10.3201/eid2609.202505 PMC 바로가기 [Article Type] Letters to the Editor