SARS-CoV-2 Seroprevalence and Clinical Features of COVID-19 in a German Liver Transplant Recipient Cohort: A Prospective Serosurvey Study독일 간 이식 수혜자 코호트에서 코로나19의 SARS-CoV-2 혈청 유병률 및 임상 특징: 전향적 혈청 조사 연구Article Published on 2021-05-012022-09-12 Journal: Transplantation proceedings [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome anti-SARS-CoV-2 anti-SARS-CoV-2 IgG Arterial hypertension assays blood sample Care clinical Clinical sign Cohort collected coronavirus COVID-19 diabetes disease eight enrolled General population Health Hospitalization increased risk Infection infections leukopenia liver nasopharyngeal Nasopharyngeal swab obesity outcome patients positive test result presenting Prospective recipient recipients reported required risk factor SARS-CoV-2 SARS-CoV-2 RNA seroconversion rate Seroprevalence Serosurvey serum IgG severe coronavirus disease severe COVID-19 source of infection subset Taking tested Transplant University Hospital Heidelberg [DOI] 10.1016/j.transproceed.2020.11.009 PMC 바로가기 [Article Type] Article
Brief Research Report: The Association Between Educational Experiences and Covid-19 Pandemic-Related Variables, and Mental Health Among Children and AdolescentsPsychiatry Published on 2021-04-292022-10-31 Journal: Frontiers in Psychiatry [Category] COVID-19, [키워드] Administered Adolescent adolescents association children cross-sectional analysis dependent variable Descriptive analysis determine education eight emotional experience First wave Health help IMPROVE independent variable lockdown Measures Mental mental health mental health problem multivariable regression model Novel coronavirus pandemic parent performed preventive intervention Probability problem problems public health authority reduced reported Schools Sociodemographic univariable variable variables wellbeing were assessed [DOI] 10.3389/fpsyt.2021.647456 PMC 바로가기 [Article Type] Psychiatry
Global Discrepancies between Numbers of Available SARS-CoV-2 Genomes and Human Development Indexes at Country Scales국가 규모에서 사용 가능한 SARS-CoV-2 게놈 수와 인간 개발 지수 간의 글로벌 불일치Brief Report Published on 2021-04-282022-09-10 Journal: Viruses [Category] MERS, SARS, 변종, [키워드] African analyzed Asia Asian capita China comparison Comparisons country country-scale development death deaths development discrepancy downloaded eight Europe European country File GDP Genome genome sequence genomes genomes sequenced GISAID database highlight Human Human Development Human Development Index Life expectancy Microsoft Excel Next-generation sequencing number Oceania Population size RANK ranking released SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-CoV-2 genomes scale Spread variant website world [DOI] 10.3390/v13050775 PMC 바로가기 [Article Type] Brief Report
Highly Accurate Chip-Based Resequencing of SARS-CoV-2 Clinical SamplesSARS-CoV-2 임상 샘플의 고정밀 칩 기반 재배열Article Published on 2021-04-272022-09-11 Journal: Langmuir : the ACS journal of surfaces and colloid [Category] SARS, 변종, [키워드] absence Accuracy appearance applied average clinical clinical samples clinical testing Contact tracing effective eight Genome greater Patient positive presence or absence Sample SARS-CoV-2 sequence sequencing method Spread spread of COVID-19 tested Typical Vaccine variants viral genome virus [DOI] 10.1021/acs.langmuir.0c02927 PMC 바로가기 [Article Type] Article
Impact of SARS-CoV-2 Pandemic and Strategies for Resumption of Activities During the Second Wave of the Pandemic: A Report From Eight Paediatric Hospitals From the ECHO NetworkPublic Health Published on 2021-04-262022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] activities activity adopted Care children clinical activity component COVID-19 cross-sectional Diagnosis eight European evaluate Health hospital hospitals Impact impacted infected patients Infection inpatient admission Intensive management network pandemic Perspective preparedness provide report respiratory response restart routine SARS CoV-2 SARS-CoV-2 SARS-CoV-2 pandemic second Significant reduction Strategy Telemedicine tertiary care hospital the SARS-CoV-2 Wave were used [DOI] 10.3389/fpubh.2021.630168 PMC 바로가기 [Article Type] Public Health
Designing a SARS-CoV-2 T-Cell-Inducing Vaccine for High-Risk Patient GroupsArticle Published on 2021-04-242022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adjuvant Administered Blood CD4 clinical trial COVID-19 eight ELISpot assay group healthy high-risk patient High-risk patients HLA molecules HLA-DR intracellular cytokine staining lipopeptide lymphocyte mononuclear cell peptide peptide vaccine performed peripheral predicted predominant SARS-CoV-2 second set single subcutaneous injection Support T cell epitope T cell response TLR vaccination Vaccine weakened were assessed [DOI] 10.3390/vaccines9050428 PMC 바로가기 [Article Type] Article
A qualitative study of physician perceptions and experiences of caring for critically ill patients in the context of resource strain during the first wave of the COVID-19 pandemicResearch Article Published on 2021-04-222022-10-28 Journal: BMC health services research [Category] COVID-19, MERS, SARS, [키워드] anticipated Anxiety Care condition conducted contributing to COVID-19 COVID-19 pandemic Critical care Critical care physicians Critically ill patient described eight female First wave health system healthcare Healthcare provider healthcare providers implication Infectious disease intensive care unit investigated median Outbreaks pandemic participant Patient care physician PROTECT qualitative research recruited required resource Resource strain resources Result Seven supplementary material thematic analysis Transmission university [DOI] 10.1186/s12913-021-06393-5 PMC 바로가기 [Article Type] Research Article
HLA-A*11:01:01:01, HLA-C*12:02:02:01-HLA-B*52:01:02:02, Age and Sex Are Associated With Severity of Japanese COVID-19 With Respiratory FailureImmunology Published on 2021-04-222022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome age allele Analysis association Asymptomatic case can be used case-control analysis center clinical marker clinician Comorbidities confounding factor coronavirus coronavirus disease COVID-19 decrease develop Diagnosis disease eight failure global health Haplotype help highest HLA HLA allele HLA gene hospitalized COVID-19 patients identify infected individual Japan Japanese knowledge majority Medicine Mild mild symptoms Mortality Next-generation sequencing outbreak pandemic Patient recruited remained respiratory risk SARS-CoV-2 sensitivity severe COVID-19 severe respiratory symptoms severity of COVID-19 Sex significantly specificity susceptibility genes susceptible Tokyo utility virus was performed WHO with COVID-19 World Health Organization [DOI] 10.3389/fimmu.2021.658570 PMC 바로가기 [Article Type] Immunology
Detection of SARS‐CoV‐2 in respiratory samples from cats in the UK associated with human‐to‐cat transmission사람에서 고양이로의 전염과 관련된 영국 고양이의 호흡기 샘플에서 SARS-CoV-2 검출Original Research Published on 2021-04-222022-09-10 Journal: The Veterinary Record [Category] Fulltext, MERS, SARS, 조류인플루엔자, 치료기술, 치료법, [키워드] Analysis Antigen cats collected conjunctivitis coronavirus COVID‐19 COVID‐19 detection eight Evidence evidence of FIVE immunofluorescence infect lung tissue Mild MONITOR mutations New coronavirus nine nucleocapsid antigen nucleotide objective occurred oropharyngeal swab oropharyngeal swabs pandemic positive quantitative PCR reference sequence respiratory Respiratory disease respiratory pathogen respiratory sample Result reverse transcriptase reverse zoonosis rhinitis RNA SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 sequence Sequencing severe respiratory disease Single nucleotide polymorphism single nucleotide polymorphisms SNP SNPs submitted tested tissue tissue samples transcriptase Transmission Viral viral genome Viral RNA virus was tested [DOI] 10.1002/vetr.247 PMC 바로가기 [Article Type] Original Research
Evidence of a dysregulated vitamin D endocrine system in SARS-CoV-2 infected patient’s lung cellsSARS-CoV-2에 감염된 환자의 폐 세포에서 조절되지 않는 비타민 D 내분비계의 증거Article Published on 2021-04-212022-09-10 Journal: Scientific Reports [Category] MERS, 유전자 메커니즘, [키워드] affected Analysis applied BALF BALF cell BALF cells Bronchoalveolar lavage fluid Cell cell cycle cells computational approach Computational approaches conserved CYP27A1 cytokine signaling dataset differentially expressed differentially expressed gene Differentially expressed genes downregulated dysregulated eight elements Endocrine endocrine system Evidence evidence of Gene Expression Genes healthy individuals immune system indirect mechanism infected cells infected with SARS-CoV-2 Infection Interaction Level lung cell lung cells modulated motif NF-κB pathway Patient patients predicted provided receptor reduced Regulation retinoid SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected cells Signaling status the cells transcriptomic transcriptomics Vitamin D vitamin D endocrine system Vitamin D receptor [DOI] 10.1038/s41598-021-87703-z PMC 바로가기 [Article Type] Article